22,522 research outputs found
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
Full text linkThe interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
Motion estimation using two-stage predictive search algorithms based on joint spatio-temporal correlation information
No full text[[abstract]]Motion estimation is one of the major problems in developing a real-time software-based video codec since it has high search complexity. In the motion estimation process, the motion field of the current block can generally be tracked from the motion fields of the neighboring blocks in the spatial and temporal directions. In this paper, two efficient fast motion estimation algorithms with a two-stage predictive search based on joint spatio-temporal correlations are proposed to reduce the search complexity. In the first stage, a rough search from the given motion vectors associated with six spatially and temporally correlated blocks attempts to find a starting point of the adequate search range that is closer to the global optimum. In the second stage, block-based gradient descent search (Liu & Feig, 1996) and predictive partial search (proposed) algorithms are used for fine search to elaborately search the adequate range from the starting point for the best motion vector. Simulation results demonstrate that our algorithms effectively reduce the average number of checked points to only 1.55% and 0.78% as compared to the full search method and yield a great performance improvement in terms of computational complexity, PSNR and bit rates as compared to full search and some well-known fast search methods. (C) 2011 Elsevier Ltd. All rights reserved.[[note]]SC
Interferon-based therapy for dialysis patients with chronic hepatitis C: progress and challenges.
No full textEfficacy of light therapy on nonseasonal depression among elderly adults: a systematic review and meta-analysis [Corrigendum]
No full textCH Chang, CY Liu, SJ Chen, HC Tsai. Neuropsychiatr Dis Treat. 2018;14:3091–3102.The authors have advised that they listed the second affiliation in the author list of the paper incorrectly. The current affiliation number 2 “Department of Psychiatry & Brain Disease Research Center, China Medical University Hospital, Taichung, Taiwan” should instead appear as “An Nan Hospital, China Medical University, Tainan, Taiwan”.Read the original articl
Nipponoserica jiankouensis Ahrens, Fabrizi & Liu 2017
No full textNipponoserica jiankouensis Ahrens, Fabrizi & Liu, 2017 Additional material examined. 1 ♂ “CH-Guizhou NE 27.V.-3.VI. 20 km NW of Jiankou 1995 Fanjing Shan-Kuaichang E. Jendek & O. Sausa leg./ CS11” (CP).Published as part of Ahrens, Dirk, Fabrizi, Silvia, Bai, Ming & Liu, Wangang, 2022, Taxonomic revision of Serica MacLeay, 1819 (sensu lato) from China and adjacent areas (Coleoptera: Scarabaeidae: Melolonthinae: Sericini), with updates on Nipponoserica Nomura, 1972, pp. 1-83 in Zootaxa 5186 (1) on page 80, DOI: 10.11646/zootaxa.5186.1.1, http://zenodo.org/record/707376
Electrochemical studies on mixtures of LiNi0.8Co0.17Al0.03O2 and LiCoO2 cathode materials for lithium ion batteries
No full textPeritoneal Inflammatory Myofibroblastic Tumor in a Brush-Tailed Porcupine (Atherurus macrourus)
No full textEpithelioid Leiomyosarcoma in the Visceral Peritoneum of an American Badger (Taxidea taxus)
No full textGrowth of RA-CH-1pLMF03, RA-CH-1<i>ΔB739_1343</i>pLMF03, and RA-CH-1<i>ΔB739_1343</i>pLMF03::<i>B739_1343</i> on TSA and TSA supplemented with 50 μM Dip.
No full textThe R. anatipestifer strains (clockwise from top left) RA-CH-1pLMF03, RA-CH-1ΔB739_1343pLMF03, and RA-CH-1ΔB739_1343pLMF03::B739-1343 were grown on TSA plates containing cefoxitin (1 μg/mL) and 0 μM Dip (A) or 50 μM Dip (B). Growth was assessed by the appearance of bacterial colonies on plates. Pictures were taken after 48 h of growth at 37°C. All the experiments were repeated three times. Representative plates are presented.</p
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