149 research outputs found
Accelerated organic matter decomposition in thermokarst lakes upon carbon and phosphorus inputs
No full textAbstract Mineralization of dissolved organic matter (DOM) in thermokarst lakes plays a non‐negligible role in the permafrost carbon (C) cycle, but remains poorly understood due to its complex interactions with external C and nutrient inputs (i.e., aquatic priming and nutrient effects). Based on large‐scale lake sampling and laboratory incubations, in combination with 13 C‐stable‐isotope labeling, optical spectroscopy, and high‐throughput sequencing, we examined large‐scale patterns and dominant drivers of priming and nutrient effects of DOM biodegradation across 30 thermokarst lakes along a 1100‐km transect on the Tibetan Plateau. We observed that labile C and phosphorus (P) rather than nitrogen (N) inputs stimulated DOM biodegradation, with the priming and P effects being 172% and 451% over unamended control, respectively. We also detected significant interactive effects of labile C and nutrient supply on DOM biodegradation, with the combined labile C and nutrient additions inducing stronger microbial mineralization than C or nutrient treatment alone, illustrating that microbial activity in alpine thermokarst lakes is co‐limited by both C and nutrients. We further found that the aquatic priming was mainly driven by DOM quality, with the priming intensity increasing with DOM recalcitrance, reflecting the limitation of external C as energy sources for microbial activity. Greater priming intensity was also associated with higher community‐level ribosomal RNA gene operon ( rrn ) copy number and bacterial diversity as well as increased background soluble reactive P concentration. In contrast, the P effect decreased with DOM recalcitrance as well as with background soluble reactive P and ammonium concentrations, revealing the declining importance of P availability in mediating DOM biodegradation with enhanced C limitation but reduced nutrient limitation. Overall, the stimulation of external C and P inputs on DOM biodegradation in thermokarst lakes would amplify C‐climate feedback in this alpine permafrost region.National Natural Science Foundation of China https://doi.org/10.13039/501100001809National Basic Research Program of China https://doi.org/10.13039/50110001216
Realist painting and its relationship to my creative practice
No full textThis thesis examines the realist art movement from its origins in France in the 1840s to its development in China in the 20th century and its impact on the author as an artist. The thesis reviews the development of realism in France, and traces its impact on Chinese conceptions of realism in the 20th century. The contemporary debates surrounding realism in China are examined and contextualised within the recent history of realism in China. Finally the thesis looks at the impact of realism on the author’s creative practice and a case is argued for the development of realist ideas in a globalised culture and its value as a cross- cultural visual language
Boosting Fenton-like reactions via single atom Fe catalysis
No full textThe maximization of the numbers of exposed active sites in supported metal catalysts is important to achieve high reaction activity. In this work, a simple strategy for anchoring single atom Fe on SBA-15 to expose utmost Fe active sites was proposed. Iron salts were introduced into the as-made SBA-15 containing the template and calcined for simultaneous decomposition of the iron precursor and the template, resulting in single atom Fe sites in the nanopores of SBA-15 catalysts (SAFe-SBA). X-ray diffraction (XRD), UV-vis diffuse reflectance spectroscopy (UV-vis DRS), high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), and extended X-ray absorption fine structure (EXAFS) imply the presence of single atom Fe sites. Furthermore, EXAFS analysis suggests the structure of one Fe center with four O atoms, and density functional theory calculations (DFT) simulate this structure. The catalytic performances of SAFe-SBA were evaluated in Fenton-like catalytic oxidation of p-hydroxybenzoic acid (HBA) and phenol. It was found that the single atom SAFe-SBA catalysts displayed superior catalytic activity to aggregated iron sites (AGFe-SBA) in both HBA and phenol degradation, demonstrating the advantage of SAFe-SBA in catalysis.Yu Yin, Lei Shi, Wenlang Li, Xuning Li, Hong Wu, Zhimin Ao, Wenjie Tian, Shaomin Liu, Shaobin Wang, and Hongqi Su
A 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer
No full textXuning Wang,1 Jianguo Zhou,2 Maolin Xu,1 Yongfeng Yan,3 Liang Huang,1 Yanshen Kuang,1 Yuansheng Liu,4 Peng Li,3 Wei Zheng,3 Hongyi Liu,3 Baoqing Jia3 1Department of General Surgery, Chinese PLA Medical School, Beijing 100853, People’s Republic of China; 2Division of Thoracic Oncology, Department of Oncology, Affiliated Hospital of Zunyi Medical University, Zunyi City 563000, Guizhou Province, People’s Republic of China; 3Department of General Surgery, Chinese PLA General Hospital, Beijing 100853, People’s Republic of China; 4School of Medicine, Nankai University, TianJing, People’s Republic of China Purpose: Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. This study aimed to explore the prognostic value of lncRNAs in CRC.Material and methods: We performed gene expression profiling to identify differentially expressed lncRNAs between 51 normal and 646 tumor tissues from The Cancer Genome Atlas database. Cox regression and robust likelihood-based survival models were used to find prognosis-related lncRNAs. A lncRNA signature was developed to predict the overall survival of patients with CRC. In addition, a receiver operating characteristic curve analysis was performed to identify the optimal cutoff with the best Youden index to divide patients into different groups based on risk level.Results: Eighty survival-related lncRNAs were identified and a 15-lncRNA signature was developed on the basis of a risk score to comprehensively predict the overall survival of patients with CRC. The prognostic value of the 15-lncRNA risk score was validated using the internal testing set and total set. The risk indicator was shown to be an independent prognostic factor (hazard ratio =2.92; 95% CI: 1.73–4.94; P<0.001). Notably, all 15 lncRNAs (AC024581.1, FOXD3-AS1, AC012531.1, AC003101.2, LINC01219, AC083967.1, AL590483.1, AC105118.1, AC010789.1, AC067930.5, AC105219.2, LINC01354, LINC02474, LINC02257, and AC079612.1) were newly found to correlate with the prognosis of patients with CRC. Furthermore, the function of 15 lncRNAs was explored through the ceRNA network. These lncRNAs regulated coding genes that were involved in many key cancer pathways.Conclusion: A 15-lncRNA expression signature was discovered as a prognostic indicator for patients with CRC, which may act as competing endogenous RNA (ceRNAs) to play a crucial role in the modulation of cancer-related pathways. These findings may allow a better understanding of the prognostic value of lncRNAs. Keywords: long noncoding RNA, colorectal cancer, survival, biomarker, competing endogenous RNA, ceRN
A Trend Analysis of Domain-Specific Literatures with Content and Co-author Network Similarity
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Research of Modern Information Technology on Tree Growth Management Decision Making Model
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