2,626 research outputs found

    sj-zip-1-pik-10.1177_14644193231211233 - Supplemental material for Research on load-sharing characteristics of six-branch herringbone gear transmission system

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    Supplemental material, sj-zip-1-pik-10.1177_14644193231211233 for Research on load-sharing characteristics of six-branch herringbone gear transmission system by Linlin Liu, Sanmin Wang, Haoran Zou, Zhibin Li and Jinshuai Ge in Proceedings of the Institution of Mechanical Engineers, Part K: Journal of Multi-body Dynamics</p

    sj-zip-1-pie-10.1177_09544089221113639 - Supplemental material for Optimization of high-efficiency tooth surface accuracy of spiral bevel gears considering machine-tool motion errors

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    Supplemental material, sj-zip-1-pie-10.1177_09544089221113639 for Optimization of high-efficiency tooth surface accuracy of spiral bevel gears considering machine-tool motion errors by Fei Li, Sanmin Wang, Peng Chen, Zhibin Li, Linlin Li and Haoran Zou in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p

    Skin-Stiffener Separation in T-Stiffened Composite Specimens in Postbuckling Condition

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    An experimental and numerical investigation was conducted to study the skin-stiffener separation of single T-shape stiffener specimens in postbuckling condition. Three specimens were manufactured with a centrally located Teflon insert, and were loaded in compression until collapse. Deformation patterns and separation evolution were monitored during the tests. To measure the full-field displacements and the strain distributions of the specimens, a digital image correlation (DIC) system was used. Skin-stiffener separation was observed and measured with an ultrasound system. Finite-element (FE) analyses were conducted to capture interlaminar damage mechanism based on the virtual crack closure technique. The numerical analysis accurately predicted the postbuckling deformation and the skin-stiffener separation behavior. The close correlation between the experimental and numerical results allows for further exploitation of the strength reserve in the postbuckling region and wider design options for the next generation of composite aircraft designs.</p

    The Effect of Health Literacy on Disease Management Self-Efficacy in Chronic Disease Patients: The Mediating Effects of Social Support and the Moderating Effects of Illness Perception

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    Hao Zou,1 Jianrong Liu,1 Dongxu Jiang,2 Linlin Hou,3 Weiliang Wang,4 Linlin Zhang5 1Nursing Department, The Second Affiliated Hospital of Xi’an Medical University, Shanxi, People’s Republic of China; 2Department of Nursing, Harbin Medical University, Heilongjiang, People’s Republic of China; 3Nursing Department, The second Affiliated Hospital of Xi’an Jiaotong University, Shanxi, People’s Republic of China; 4Nursing Department, Xuzhou Medical university, Jiangsu, People’s Republic of China; 5Department of Nursing, School of Pharmacy, Changzhou University, Jiangsu, People’s Republic of ChinaCorrespondence: Jianrong Liu; Linlin Zhang, Email [email protected]; [email protected]: To test a hypothetical pathway model to estimate the links between health literacy, social support, illness perception, and disease management self-efficacy.Methods: This cross-sectional study, conducted from June to October 2022, involved the recruitment of 210 patients with chronic diseases at two primary care facilities. Participants completed the Health Literacy Management Scale, Self-Efficacy for Managing Chronic Disease 6-Item Scale, Social Support Rating Scale and Brief Illness Perception Questionnaire. We used the PROCESS macro for R to determine the hypothetical pathway model.Results: The direct effect of health literacy on self-efficacy was significant (β=0.1792, 95% CI: 0.0940– 0.2644), and social support played a partial mediating role between health literacy and self-efficacy (ES=0.0761, 95% CI: 0.0398– 0.1204). Illness perception moderated the relationship between social support and self-efficacy (β=− 0.0153, 95% CI: − 0.0268- − 0.0039).Conclusion: Proposed a conceptual model including the mediating effect of social support and the moderating effect of illness perception, which helps to clarify the underlying mechanisms between health literacy and self-efficacy.Keywords: health literacy, self efficacy, moderated mediation analysi

    Finite Element Methods and Their Convergence for Elliptic and Parabolic Interface Problems

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    In this paper, we consider the finite element methods for solving second order elliptic and parabolic interface problems in two-dimensional convex polygonal domains. Nearly the same optimal L 2 -norm and energy-norm error estimates as for regular problems are obtained when the interfaces are of arbitrary shape but are smooth, though the regularities of the solutions are low on the whole domain. The assumptions on the finite element triangulation are reasonable and practical. Mathematics Subject Classification (1991): 65N30, 65F10. A running title: Finite element methods for interface problems. Correspondence to: Dr. Jun Zou Email: [email protected] Fax: (852) 2603 5154 1 Institute of Mathematics, Academia Sinica, Beijing 100080, P.R. China. Email: [email protected]. The work of this author was partially supported by China National Natural Science Foundation. 2 Department of Mathematics, the Chinese University of Hong Kong, Shatin, N.T., Hong Kong. E-mail: [email protected]...

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    Hoe zou een publieke datadonatiepraktijk ten behoeve van gezondheid en welzijn eruit kunnen zien?

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    Dit boekje is verslag van het CHANGE! (Conscious Health dAta shariNg in movinG RottErdam!) project dat is uitgevoerd in 2021-22 in het kader van een Open Mind subsidie van het Convergence programma dat ten doel heeft samenwerking tussen TU Delft, Erasmus Universiteit Rotterdam en Erasmus Medisch Centrum te bespoedigen. Het stimuleert allianties van onderzoekers van de verschillende universiteiten om in samenwerking met publieke en private partners innovatieve bijdragen te leveren aan urgente en complexe maatschappelijke uitdagingen, zoals klimaatverandering, duurzaamheid, gezondheidszorg, verstedelijking en digitalisering.Dit (kleine, verkennende) interdisciplinaire project, uitgevoerd binnen het Health &amp; Technology programma, betreft een onderzoek naar hoe een publieke datadonatiepraktijk ten behoeve van gezondheid en welzijn eruit zou kunnen zien. Het is een ultiem Convergence-project, omdat het grensoverschrijdend is voor elk van de participerende instituten en kennisdomeinen en expertise van het team. Binnen CHANGE! zijn onder andere de medische, ethische, sociaal-maatschappelijke, politieke en ruimtelijke (en niet strikt de technische) aspecten van het verzamelen en werken met gezondheidsdata verkend.Design Aesthetic

    Efficient Fiber-shaped Devices for Energy Conversion and Storage

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    CPCI-S(ISTP)175-17

    Safety and Efficacy of Concurrent or Sequential Radiotherapy Plus (PD-1) Inhibitors in Oligometastatic Esophageal Cancer

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    Yanan Duan,1,2 Wenru Qin,1,3 Linlin Yang,1,4 Bing Zou,1 Wenting Qie,1,3 Ruiting Song,1,2 Lu Xue,1,2 Linlin Wang1 1Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, People’s Republic of China; 2Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, People’s Republic of China; 3Weifang Medical University, Weifang, People’s Republic of China; 4Cheeloo College of Medicine, Shandong University, Jinan, People’s Republic of ChinaCorrespondence: Linlin Wang, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Science, Jinan, Shandong, People’s Republic of China, Email [email protected]: We assess real-world outcomes, including safety and efficacy, of concurrent or sequential treatment with radiotherapy plus programmed cell death protein 1 (PD-1) inhibitors in patients with oligometastatic esophageal cancer (OMEC).Methods: This cohort study retrospectively collected clinical data of patients with synchronous or metachronous OMEC. All patients underwent concurrent or sequential treatment with radiotherapy plus PD-1 inhibitors. Each patient had up to five measurable metastatic lesions and up to three organs involved. Study endpoints were progression-free survival (PFS), treatment-related toxicities, locoregional progression-free survival (LRPFS), objective response rate (ORR), and disease control rate (DCR). Description statistics and Kaplan–Meier models were used for statistical analysis.Results: A total of 86 patients were included, most of whom were diagnosed with squamous cell carcinoma histology (98%) and presented with synchronous OMEC (64%). The median follow-up period was 17 months (range: 6– 32 months), the median PFS was 15.2 months (95% confidence interval: 12.1– 18.2 months); and the 1- and 2-year PFS rates were 61.4% and 26.7%, respectively. The 1- and 2-year LRPFS were 91.3% and 57.3%, respectively. The ORR and DCR were 46.5% and 91.8%, respectively. Forty-two patients (48.8%) experienced grade 3 or higher treatment-related adverse events (TRAEs); a grade 5 treatment-related adverse event was observed in one patient (1.2%) who died of immune-related pneumonitis.Conclusion: Combining radiotherapy with PD-1 inhibitors is a safe and effective treatment option for patients with OMEC. No new safety concerns were identified in this study. However, due to the potential risk of cumulative toxicity, an individual risk-benefit assessment for each patient is required prior to treatment initiation.Keywords: oligometastatic disease, esophageal cancer, PD-1 inhibitors, radiotherap

    Wanted! Investigating how elements from the personal usage context affect Gen Z consumers' value-in-use experience and engagement with mobile service

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    sponsorship: The research underlying this article has benefitted from a China Scholarship Council grant (No. 201508320285) to the first author. (China Scholarship Council|201508320285)status: Publishe
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