184 research outputs found

    Management of the Diseases of Mesenteric Arteries and Veins:Clinical Practice Guidelines of the European Society of Vascular Surgery (ESVS)

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    These guidelines are dedicated to Paola De Rango, University of Perugia, Italy. She participated very actively in the process of developing these guidelines, in particular the important chapters on chronic arterial and venous mesenteric ischaemia. Six days after the second meeting of the task force she died unexpectedly, to our great despair and loss. We honour her dedication and scientific integrity by completing these guidelines. Among many other commitments she was a very productive reviewer and an associate editor of this journal. You can read more about Paola's important contributions to science and to the vascular community in the April 2016 issue of the European Journal of Vascular and Endovascular Surgery. 1[Figure presented] Dr Paola De Rango, July 28, 1966 – February 21, 2016 </p

    Abdominal aortic aneurysms do not develop more aggressively among patients with a positive family history of the disease

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    Title:Abdominal aortic aneurysms no not develop more aggressively among patients with a positive family history of the diseaseAuthors:Trine M. M. Joergensen, Holger Wemmelund, Anders Green, Jes Lindholt, Kim Houlind. Introduction:It is well known, that a family history of abdominal aortic aneurysm (AAA) strongly increases the risk of developing AAA, but it is still uncertain whether familial AAA’s develops differently than non-familial AAA’s.Objectives:To investigate whether familial AAA’s develop more aggressively than non-familial AAA’s by looking at growth rate, risk of surgery and rupture, as well as the size of the aneurysm at the time of diagnosis and the patient´s age at the time of operation, rupture and diagnosis.Design:Observational retrospective longitudinal studyMaterials:318 patients (273 men and 45 women) with AAA diagnosed between 1996-2008 in Jutland, Denmark with information on family history of AAA, diameter of AAA throughout follow-up, surgery, ruptures, comorbidity, smoking, and use of medication. Methods:Patients with and without a family history of AAA were compared regarding mean age at diagnosis and surgery, diameter of AAA at diagnosis, risk of surgery and rupture as well as comorbidity and use of medication. Mean growth rates were compared between the two groups and a mixed effects model was fitted to control for possible confounders.Results:Patients with a family history of AAA were significantly younger than patients with no family history of the disease (69.8 vs. 72.4 years, p=0.032), but we found no significant differences regarding age at operation (72.2 vs. 70.6, p=0.204) or regarding the proportion of patients experiencing rupture (16.0 vs. 10.6%, p=0.226) or undergoing surgery (78.2 % vs. 81.7 %, p=0.484). We found no significant difference in growth rates between the two groups (5.25 mm/year (95%CI: 3.73;6.78) for patients with positive family history and 6.19 mm/year (95%CI: 4.40;7.97) for patients with no family history of AAA (p=0.490)).Conclusions:We found no evidence to suggest that abdominal aortic aneurysms develop more aggressively among patients with a positive family history of the disease.<br/

    Abdominal aortic aneurysms do not develop more aggressively among patients with a positive family history of the disease

    No full text
    Title:Abdominal aortic aneurysms no not develop more aggressively among patients with a positive family history of the diseaseAuthors:Trine M. M. Joergensen, Holger Wemmelund, Anders Green, Jes Lindholt, Kim Houlind. Introduction:It is well known, that a family history of abdominal aortic aneurysm (AAA) strongly increases the risk of developing AAA, but it is still uncertain whether familial AAA’s develops differently than non-familial AAA’s.Objectives:To investigate whether familial AAA’s develop more aggressively than non-familial AAA’s by looking at growth rate, risk of surgery and rupture, as well as the size of the aneurysm at the time of diagnosis and the patient´s age at the time of operation, rupture and diagnosis.Design:Observational retrospective longitudinal studyMaterials:318 patients (273 men and 45 women) with AAA diagnosed between 1996-2008 in Jutland, Denmark with information on family history of AAA, diameter of AAA throughout follow-up, surgery, ruptures, comorbidity, smoking, and use of medication. Methods:Patients with and without a family history of AAA were compared regarding mean age at diagnosis and surgery, diameter of AAA at diagnosis, risk of surgery and rupture as well as comorbidity and use of medication. Mean growth rates were compared between the two groups and a mixed effects model was fitted to control for possible confounders.Results:Patients with a family history of AAA were significantly younger than patients with no family history of the disease (69.8 vs. 72.4 years, p=0.032), but we found no significant differences regarding age at operation (72.2 vs. 70.6, p=0.204) or regarding the proportion of patients experiencing rupture (16.0 vs. 10.6%, p=0.226) or undergoing surgery (78.2 % vs. 81.7 %, p=0.484). We found no significant difference in growth rates between the two groups (5.25 mm/year (95%CI: 3.73;6.78) for patients with positive family history and 6.19 mm/year (95%CI: 4.40;7.97) for patients with no family history of AAA (p=0.490)).Conclusions:We found no evidence to suggest that abdominal aortic aneurysms develop more aggressively among patients with a positive family history of the disease.<br/

    Screening for aortaanneurisme: Ideologisk korstog eller ny evidens?

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    Er der kommet resultater, der vender op og ned på, hvad vi ved om fordele og ulemper ved screening for abdominal aortaaneurisme i dansk kontekst, spørger to professorer i kommentar til videnskabelig leder
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