215,932 research outputs found
Threatened fishes of the world: Tanichthys albonubes Lin 1932 (Cyprinidae)
No full textThe white cloud mountain minnow Tanichthys albonubes Lin is an endemic species to southern China and the genus has two species, Tanichthys albonubes Lin and Tanichthys micagemmae Freyhof et Herder. The distribution range of T. albonubes Lin and T. micagemmae is very narrow and only found in the mountain brooks of Baiyunshan Mountain (White Cloud Mountain), Huaxian Country and the vicinity of Guangzhou in Guangdong Province and Halong, Quang Ninh Province, Vietnam respectively. The wild populations of this fish had already been on the verge of extinction when Shu-Yan Lin first discovered it in 1932 at the Baiyunshan Mountain. It was believed to be extinct in the wild because there were no reports of this fish in the wild since 1980. In September 2003, a small and isolated population of the fish was discovered in a mountain puddle in the north vicinity of Guangzhou. Additional studies are needed to determine the survival and propagation of the released fish. The protection of their natural habitat should be implemented.The white cloud mountain minnow Tanichthys albonubes Lin is an endemic species to southern China and the genus has two species, Tanichthys albonubes Lin and Tanichthys micagemmae Freyhof et Herder. The distribution range of T. albonubes Lin and T. micagemmae is very narrow and only found in the mountain brooks of Baiyunshan Mountain (White Cloud Mountain), Huaxian Country and the vicinity of Guangzhou in Guangdong Province and Halong, Quang Ninh Province, Vietnam respectively. The wild populations of this fish had already been on the verge of extinction when Shu-Yan Lin first discovered it in 1932 at the Baiyunshan Mountain. It was believed to be extinct in the wild because there were no reports of this fish in the wild since 1980. In September 2003, a small and isolated population of the fish was discovered in a mountain puddle in the north vicinity of Guangzhou. Additional studies are needed to determine the survival and propagation of the released fish. The protection of their natural habitat should be implemented
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
No full textGenetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy. To determine whether vascular endothelial growth factor A (VEGF-A) produced by tumor-associated macrophages regulated the onset of the angiogenic switch, a genetic approach was used to restore expression of VEGF-A into tumors at the benign stages. This stimulated formation of a high-density vessel network and in macrophage-depleted mice, was followed by accelerated tumor progression. The expression of VEGF-A led to a massive infiltration into the tumor of leukocytes that were mostly macrophages. This study suggests that macrophage-produced VEGF regulates malignant progression through stimulating tumor angiogenesis, leukocytic infiltration and tumor cell invasion
LIN-1 sumoylation is required for ventral toroid contraction.
No full text(A) Wild-type and K10A, K169A mutant LIN-1::GFP expression in L3 larvae at the Pn.px stage after VPC-specific degradation of AID::SMO-1 from the L2 stage onward. The 1° and 2° VPC descendants are underlined in white. The left panels show the corresponding DIC images overlaid with the LIN-1::GFP signal in green. (B) Quantification of LIN-1::GFP expression levels in 1° and 2° VPC descendants at the Pn.px stage in LIN-1::GFP wild-type and K10A, K169A double mutants under the indicated conditions. See S3 Fig for the corresponding measurements at the Pn.pxx stage. (C) Toroid morphogenesis defects in LIN-1 K10A and K169A single and double mutants at the L4 stage. Left panels show lateral views of z-projections. vulA and vulB1 toroids are outlined by the white rectangle in the top left panel and shown in top (xz) views in the right panels. (D) Quantification of vulA contraction, calculated as the ratio of the vulA and vulB1 toroid diameter. The box plots show the median values with the 25th and 75th percentiles and the whiskers indicate the maximum and minimum values. Where indicated, untreated controls are labelled with–IAA (blue) and animals treated with 1 mM auxin with +IAA (red). In each graph, the numbers of animals scored are indicated by the numbers in brackets. Statistical significance in (B) and (D) was calculated with unpaired two-tailed t-tests. p-values are indicated as * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001. The scale bars are 10 μm.</p
SPATIAL CHOW-LIN METHODS: BAYESIAN AND ML FORECAST COMPARISONS
No full textCompleting data that are collected in disaggregated and heterogeneous spatial units is a quite frequent problem in spatial analyses of regional data. Chow and Lin (1971) (CL) were the rst to develop a uni ed framework for the three problems (interpolation, extrapolation and distribution) of predicting disaggregated times series by so-called indicator series. This paper develops a spatial CL procedure for disaggregating cross-sectional spatial data and compares the Maximum Likelihood and Bayesian spatial CL forecasts with the naive pro rata error distribution. We outline the error covariance structure in a spatial context, derive the BLUE for the ML estimator and the Bayesian estimation procedure by MCMC. Finally we
apply the procedure to European regional GDP data and discuss the disaggregation assumptions. For the evaluation of the spatial Chow-Lin procedure we assume that only NUTS 1 GDP is known and predict it at NUTS 2 by using employment and spatial information available at NUTS 2. The spatial neighborhood is de ned by the inverse travel time by car in minutes. Finally, we present the forecast accuracy criteria comparing the predicted values with the actual observations.
Probing and extracting the structure of vibrating SF6 molecules with inner-shell photoelectrons
No full textCitation: Nguyen, N. T., Lucchese, R. R., Lin, C. D., & Le, A. T. (2016). Probing and extracting the structure of vibrating SF6 molecules with inner-shell photoelectrons. Physical Review A, 93(6), 9. doi:10.1103/PhysRevA.93.063419We propose a scheme for probing the structure of vibrating molecules with photoelectrons generated from ultrashort soft-x-ray pulses. As an example we analyze below-100-eV photoelectrons liberated from the S(2p) orbital of vibrating SF6 molecules to image very small structural changes of molecular vibration. In particular, photoionization cross sections and photoelectron angular distributions (PAD) at nonequilibrium geometries can be retrieved accurately with photoelectrons near the shape resonance at 13 eV. This is achieved with a pump-probe scheme, in which the symmetric stretch mode is first Raman excited predominantly by a relatively short laser pulse and then later probed at different time delays by a few-femtosecond soft-x-ray pulse with photon energy near 200 eV
Spiranthes nivea var. nivea T. P. Lin & W. M. Lin 2011
No full textSpiranthes nivea T.P. Lin & W.M. Lin (2011: 320) var. nivea — Fig. 4. Type:— TAIWAN. Pingtung: Tahanshan, 20 May 2009, Y.F. Wang s.n. (holotype: TAI 270634!). Synonym:— Spiranthes suishaensis auct. non (Hayata 1916: 86) Schlechter (1919: 161): Lin (2016: 117). Morphological descriptions and illustrations: —See Lin & Lin (2011: 320; f. 5), Surveswaran et al. (2017: 125; f. 4), Hsu & Chung (2016: 188), as Spiranthes suishaensis, and Lin (2019: 266; f. 117; pl. 13). Distribution and ecology: —The typical variety species is only recorded from the type locality, Tahanshan (Mt. Tahan) in southern Taiwan. It grows on semi-open roadside slopes around 1400–1600 m elev. and flowers from March to April. Additional specimens examined: — TAIWAN. Pingtung Co.: Mt. Tahan, 13 March 2013, T.-C. Hsu 6342 (TAIF!); Tahanshan, 9 April 2013, S.-S. Lin s.n. (TAI!). Taxonomic remarks: — Spiranthes nivea is most similar to S. hongkongensis, but it differs in having nearly glabrous labellum disc, smaller glabrous basal labellum callosities, and sparsely pubescent glabrous rachis, ovaries, and sepals.Published as part of Suetsugu, Kenji & Hsu, Tian-Chuan, 2023, Taxonomic revision of the genus Spiranthes (Orchidaceae) in Taiwan, pp. 1-10 in Phytotaxa 578 (1) on page 5, DOI: 10.11646/phytotaxa.578.1.1, http://zenodo.org/record/751762
Munidopsis sarissa Lin, Osawa & Chan 2007
No full textMunidopsis sarissa Lin, Osawa & Chan, 2007 Munidopsis sarissa Lin et al., 2007: 167, figs 1–3 (Taiwan, 960–1010 m). Type data: holotype, male, NTOU A008820. Type locality: Taiwan, 22º17.16´N, 119º59.91´E, 960–972 m.Published as part of Baba, Keiji, Macpherson, Enrique, Poore, Gary C. B., Ahyong, Shane T., Bermudez, Adriana, Cabezas, Patricia, Lin, Chia-Wei, Nizinski, Martha, Rodrigues, Celso & Schnabel, Kareen E., 2008, Catalogue of squat lobsters of the world (Crustacea: Decapoda: Anomura-families Chirostylidae, Galatheidae and Kiwaidae), pp. 1-220 in Zootaxa 1905 (1) on page 158, DOI: 10.11646/zootaxa.1905.1.1, http://zenodo.org/record/513458
The Tyrosine Phosphatase CD148 is Excluded from the Immunologic Synapse and Down-regulates Prolonged T Cell Signaling
No full text?? Joseph Lin and Arthur Weis, 2011. Originally published in The Journal of Cell Biology. doi: 10.1083/jcb.200303040.CD148 is a receptor-like protein tyrosine phosphatase\ud
up-regulated on T cells after T cell receptor\ud
(TCR) stimulation. To examine the physiologic role\ud
of CD148 in TCR signaling, we used an inducible CD148-\ud
expressing Jurkat T cell clone. Expression of CD148 inhibits\ud
NFAT (nuclear factor of activated T cells) activation induced\ud
by soluble anti-TCR antibody, but not by antigen-presenting\ud
cells (APCs) loaded with staphylococcal enterotoxin superantigen\ud
(SAg) or immobilized anti-TCR antibody. Immunofluorescence\ud
microscopy revealed that the extracellular\ud
C\ud
domain of CD148 mediates its exclusion from the immunologic\ud
synapse, sequestering it from potential substrates.\ud
Targeting of the CD148 phosphatase domain to the immunologic\ud
synapse potently inhibited NFAT activation by all\ud
means of triggering through the TCR. These data lead us to\ud
propose a model where CD148 function is regulated in\ud
part by exclusion from substrates in the immunologic synapse.\ud
Upon T cell???APC disengagement, CD148 can then\ud
access and dephosphorylate substrates to down-regulate\ud
prolongation of signaling.This work was supported in part by research funds from the state of California
Does Downloading PowerPoint Slides Before the Lecture Lead to Better Student Achievement?: Reply
No full textThis reply responds to a comment by Cannon (2011) that opens the debate on consistency of the effect of downloading PowerPoint slides before lectures on students’ exam performance. Cannon (2011) points out potential endogeneity problems in Chen and Lin (2008) and attempts to explore the unconditional mean effect of downloading PowerPoint slides for the full sample. In this reply, we firstly argue that the estimates in our original article are consistent since the effect of interest is the “conditional†treatment effect but not the unconditional mean effect. We provide explanations for our rationale of estimating the “conditional†treatment effect. Secondly, we propose a modified downloading variable to replicate Cannon’s analysis. Our results suggest that downloading PowerPoint slides before the exam does not produce a significant effect on absent students’ exam performance which is different from the results in Cannon (2011). Our analysis does support Cannon’s argument that students fixed effects are different across different attendance status.
Lin (Helen T.) : Essential grammar for modern chinese
No full textAlleton Viviane. Lin (Helen T.) : Essential grammar for modern chinese. In: Cahiers de linguistique - Asie orientale, vol. 11 1, 1982. pp. 109-110
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