1,721,108 research outputs found
Greatly increased risk for prostatic abscess following pyogenic liver abscess: A nationwide population-based study
Association Between Epilepsy and Erectile Dysfunction: Evidence from a Population-Based Study
Introduction. Although the association between epilepsy and sexual disorders has long been known, very few studies have attempted to explore the association between epilepsy and erectile dysfunction (ED). Aim. This population-based case-control study aimed to investigate the association between ED and a prior diagnosis with epilepsy. Methods. This study used data from the Longitudinal Health Insurance Database 2000 in Taiwan. The cases comprised 6,427 patients with a diagnosis of ED and 32,135 controls who were frequency matched with cases based on 10-year age groups and index year. Conditional logistic regression was used to calculate the odds ratios (ORs) for prior epilepsy. Main Outcome Measure. The prevalence and risk of epilepsy between cases and controls. Results. Of the sampled patients, 3,861 (14%) were diagnosed before the index date: 1,358 individuals (19.7%) were cases and 2,503 (12.1%) were controls. After adjusting for hypertension, diabetes, hyperlipidemia, renal disease, coronary heart disease, obesity, alcohol abuse/alcohol dependence syndrome, and socioeconomic status, conditional logistic regression analysis revealed that patients with ED were more likely to have been diagnosed with prior epilepsy than controls (OR = 1.83, 95% CI = 1.512.21). Compared with controls, the adjusted ORs for prior generalized epilepsy and partial epilepsy for cases were 2.13 (95% CI = 1.523.00) and 1.64 (95% CI = 1.312.06), respectively. The most pronounced associations were detected in ED cases aged between 30 and 39 who were 3.04 (95% CI = 1.675.50) times more likely than controls to have been previously diagnosed with epilepsy. Conclusions. Our findings suggest a positive correlation between ED and a prior diagnosis with epilepsy. Keller J, Chen Y-K, and Lin H-C. Association between epilepsy and erectile dysfunction: Evidence from a population-based study. J Sex Med 2012;9:22482255
Delayed Parenthood and the Risk of Cesarean Delivery: Is Paternal Age an Independent Age an Independent Risk Factor?
A case-control study on the association between chronic prostatitis/chronic pelvic pain syndrome and erectile dysfunction
OBJECTIVE ;To examine the association between erectile dysfunction (ED) and a previous diagnosis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using a population-based dataset. ;PATIENTS AND METHODS ;The data for this case-control study was obtained from the National Health Insurance database. ;A total of 3194 males, who were >= 18 years of age when they first received a diagnosis of ED, were identified and 15 970 controls were randomly selected. ;The prevalence and risk of CP/CPPS among cases and controls were calculated by using conditional logistic regression analysis. ;RESULTS ;In total, 667 (3.5%) of the 19 164 sampled subjects had been diagnosed with CP/CPPS before the index date; CP/CPPS was found in 276 (8.6%) cases and in 391 (2.5%) controls (P < 0.001). ;Regression analysis indicated that cases were more likely to have had previous CP/CPPS (odd ratio 3.62, 95% confidence interval 3.07-4.26) after adjusting for patient monthly income, geographical location and urbanization level, as well as hypertension, diabetes, coronary heart disease, renal disease, obesity and alcohol abuse/alcohol dependence syndrome status, when compared with controls. ;CONCLUSIONS ;We conclude that there was an association between ED and having been previously diagnosed with CP/CPPS. ;Urologists should be alert to the association between CP/CPPS and ED, and assess the erectile function of patients suffering from CP/CPPS
Increased risk of depressive disorder within 1 year after diagnosis with urinary calculi in Taiwan
This study investigated the risk of subsequent depressive disorders (DD) following a diagnosis of urinary calculi (UC) in Taiwan. In total, 67,917 adult patients newly diagnosed with UC were recruited, along with 153,951 age-matched enrollees who were used as a comparison group. A stratified Cox proportional hazard regression analysis revealed that the adjusted hazard of DD within a 1-year period following diagnosis with UC was 1.75 times greater for patients with UC than for comparison patients. (C) 2012 Elsevier Ireland Ltd. All rights reserved
A Case-Control Analysis on the Association Between Erectile Dysfunction and Sudden Sensorineural Hearing Loss in Taiwan
Introduction. Although the cause of sudden sensorineural hearing loss (SSNHL) is yet to be elucidated, many theories have been proposed regarding potentially contributory etiologies. One increasingly well-supported theory purports an underlying vascular pathomechanism. If this is the case, SSNHL may also associate with conditions comorbid with vascular diseases, such as erectile dysfunction (ED). However, no studies to date have investigated the association between ED and SSNHL. Aim. This study set out to estimate a putative association between ED and having been previously diagnosed with SSNHL using a population-based dataset with a case-control design. Methods. This study used administrative claim data from the Taiwan National Health Insurance program. We identified 4,504 patients with ED as the study group and randomly selected 22,520 patients as the comparison group. Conditional logistic regression was used to examine the association between ED and having previously received a diagnosis of SSNHL. Main Outcome Measure. The prevalence and risk of SSNHL between cases and controls were calculated. Results. Of the sampled patients, 41 (0.15%) had been diagnosed with SSNHL before the index date; 22 (0.49% of the cases) were from the study group and 19 (0.08% of controls) were from the control group. Conditional logistic regression analysis revealed that after adjusting for the patient's monthly income, geographic location, hypertension, diabetes, hyperlipidemia, coronary heart disease, obesity, and alcohol abuse/alcohol dependence syndrome status, patients with ED were more likely than controls to have been diagnosed with SSNHL before the index date (odds ratio = 6.06, 95% confidence interval = 3.2511.29). Conclusions. There was an association between ED and prior SSNHL. The results of this study add to the evidence supporting an underlying vascular pathomechanism regarding the development of SSNHL and highlight a need for clinicians dealing with SSNHL patients to be alert to the development of ED. Keller JJ, Chen Y-K, and Lin H-C. A case-control analysis on the association between erectile dysfunction and sudden sensorineural hearing loss in Taiwan. J Sex Med 2012;9:14111417
Association of Erectile Dysfunction with Atopic Dermatitis: A Population-Based Case-Control Study
Introduction. Some studies have highlighted the high prevalence of erectile dysfunction (ED) in patients with dermatological diseases such as psoriasis, chronic hand eczema, and systemic sclerosis. However, to date, there is still no study that has explored the relationship between ED and atopic dermatitis (AD). ;Aim. Using a population-based data set, this case-control study aimed to examine the association of ED with prior AD by comparing the risk of prior AD between patients with ED and matched controls in Taiwan. ;Methods. This study used administrative claims data from the Taiwan National Health Insurance program. We identified 3,997 patients with newly diagnosed ED as cases and randomly selected 19,985 subjects without a history of ED as controls. Conditional logistic regression was used to calculate the odds ratio (OR) and corresponding 95% confidence interval (CI) for previously diagnosed AD between cases and controls. ;Main Outcome Measure. The prevalence and risk of having been previously diagnosed with AD between cases and controls were calculated. ;Results. Of the 23,982 sampled subjects, 1,758 (7.3%) had been previously diagnosed with AD; it was found among 425 (10.6%) cases and among 1,333 (6.7%) controls (P < 0.001). Conditional logistic regression analysis demonstrated that cases were more likely to have prior AD than controls (OR = 1.60, 95% CI = 1.42- 1.80, P < 0.001) after adjusting for monthly income, geographic location, urbanization level, hypertension, diabetes, coronary heart disease, hyperlipidemia, obesity, and alcohol abuse/alcohol dependence syndrome. ;Conclusions. There was an association between ED and prior AD. We suggest that clinicians should be more attentive to sexual complaints from patients with AD. Chung S-D, Keller JJ, and Lin H-C. Association of erectile dysfunction with atopic dermatitis: A population-based case-control study. J Sex Med 2012; 9: 679-685
Increased risk of pneumonia following pyogenic liver abscess: a nationwide population-based study
Objective: This nationwide study aimed to estimate the risk of pneumonia during a 90-day period following diagnosis with pyogenic liver abscess (PLA) compared to individuals who did not suffer PLA. ;Methods: We investigated the incidence of pneumonia during the 90 days after diagnosis of PLA among 12 868 patients who received medical services for this condition, and compared it to that of 64 340 controls who received medical services for other medical conditions. ;Results: We found that the incidence rates of pneumonia were 9.59 and 1.87 per 10 000 person-days in patients with and without PLA, respectively. Stratified Cox proportional hazard regressions found that the hazard ratio for pneumonia among patients with PLA was 5.28 times higher than that of patients without PLA after adjusting for potential confounding factors. We further found Klebsiella pneumoniae to be the causative organism in 84.9% of the cases, but in only 11.7% of the comparison group. ;Conclusions: Our study suggests an increased risk of pneumonia among individuals who have suffered a PLA. (C) 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved
A case-control study of chronic prostatitis/chronic pelvic pain syndrome and colorectal cancer
OBJECTIVE ;To estimate the association between chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and colorectal cancer (CRC) using a nationwide population-based data set. ;PATIENTS AND METHODS ;This case-control study used data sourced from the Taiwan Longitudinal Health Insurance Database. ;The cases comprised 2899 patients with CRC and 14 995 randomly selected subjects as controls. ;We used conditional logistic regression to examine the association between CRC and previous diagnosis of CP/CPPS. ;RESULTS ;Of the sampled patients, 531(3.05%) had been diagnosed with CP/CPPS before the index date, with 123 (4.24% of the patients with CRC) coming from the cases and 408 individuals (2.81% of patients without CRC) coming from the controls. ;Conditional logistic regression analysis revealed that cases were more likely to have CP/CPPS than controls (odds ratio 1.45, 95% CI 1.17-1.79, P < 0.001) after adjusting for the monthly income, geographic location, urbanization level, hypertension, diabetes, renal disease, obesity and cystic kidney disease. ;In subgroup analysis, we found the magnitude of the association to be higher in subjects younger than 60 years (age 40-49, odds ratio 2.01; 95% CI 2.04-3.58 and aged 50-59, 2.40, 95% CI 1.48-3.87, both P < 0.001) than among other age groups. ;CONCLUSION ;We conclude that CP/CPPS patients are at higher risk for CRC, especially in males under 60 years of age
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