128,907 research outputs found
LIN-1 sumoylation is required for ventral toroid contraction.
(A) Wild-type and K10A, K169A mutant LIN-1::GFP expression in L3 larvae at the Pn.px stage after VPC-specific degradation of AID::SMO-1 from the L2 stage onward. The 1° and 2° VPC descendants are underlined in white. The left panels show the corresponding DIC images overlaid with the LIN-1::GFP signal in green. (B) Quantification of LIN-1::GFP expression levels in 1° and 2° VPC descendants at the Pn.px stage in LIN-1::GFP wild-type and K10A, K169A double mutants under the indicated conditions. See S3 Fig for the corresponding measurements at the Pn.pxx stage. (C) Toroid morphogenesis defects in LIN-1 K10A and K169A single and double mutants at the L4 stage. Left panels show lateral views of z-projections. vulA and vulB1 toroids are outlined by the white rectangle in the top left panel and shown in top (xz) views in the right panels. (D) Quantification of vulA contraction, calculated as the ratio of the vulA and vulB1 toroid diameter. The box plots show the median values with the 25th and 75th percentiles and the whiskers indicate the maximum and minimum values. Where indicated, untreated controls are labelled with–IAA (blue) and animals treated with 1 mM auxin with +IAA (red). In each graph, the numbers of animals scored are indicated by the numbers in brackets. Statistical significance in (B) and (D) was calculated with unpaired two-tailed t-tests. p-values are indicated as * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001. The scale bars are 10 μm.</p
Ocena trwałości lin pracujących w górniczych wyciągach szybowych
W artykule przedstawiono problematykę trwałości lin nośnych i wyrównawczych eksploatowanych w wybranych szybach kopalń głębinowych. Opisano podstawowe przyczyny zużywania się lin wyciągowych, podano metody oceny zużycia lin stalowych, przedstawiono także kryteria oceny trwałości lin nośnych wyciągowych. Autor zaprezentował również wybrane wyniki z wydłużeń lin nośnych wyciągowych. Artykuł zakończony jest wnioskami wynikającymi z przeprowadzonych badań. Artykuł został także opatrzony zdjęciami przedstawiającymi aparaturę pomiarową, wykorzystywaną do oceny trwałości lin stalowych oraz stalowo-gumowych. W artykule przytoczono zostały kryteria oceny trwałości lin nośnych
Exploring the Systemic and Speculative dimensions into Service Design
The scale and process of Service Design are expanding and evolving as the emerging challenges they face become increasingly complex and uncertain. In order to cope with the systemic complexity and uncertainty of future changes when designing service (eco)systems, more holistic and speculative dimensions are needed to be considered. In the field of design, Systemic Design and Speculative Design are considered to have the capacities to deal with systemic complexity and critically consider future uncertainty. Therefore, this study aims to explore from the theoretical level to the operational level to understand if and how Systemic Design and Speculative Design can help to expand the Systemic and Speculative dimensions into Service Design. Through literature review and expert interviews, this paper presents the theoretical relationships between these three approaches and discusses the opportunities and criticalities of approach integration. In the end, we propose three future research directions and open up open questions about Service Design evolution in Systemic and Speculative dimensions
Integrating Speculative and Systemic Perspectives into Service Design Education in the Chinese Context
Service design education needs to evolve to equip students for complex and uncertain futures. In China, however, it remains dominated by linear, solution-oriented, and short-term mindsets, limiting the cultivation of students’ future-oriented and systemic capabilities. This study explores how integrating speculative and systemic design approaches can reinforce service design education. Drawing on a literature review, three workshops with students, and expert interviews, the findings show that such integration can help students shift from isolated, solution-oriented thinking toward more relational, holistic, reflective, and futures-oriented reasoning, moving from fixed solutions to enabling conditions for ongoing transformation. The study contributes to exploring alternative pedagogical pathways that support more adaptive and future-ready service design models
Program for LIN communication
V diplomi je predstavljena LIN komunikacija, uporabljena strojna in programska oprema za vzpostavitev le-te med dvema elektronskima vezjema z Microchip 18F procesorjema. Opisani so zapisi nastavitev v njim namenjenih zbirkah, vsi načini vpisovanja nastavitev, seznami vseh zahtevanih datotek, oziroma knjižnic, ter z diagrami poteka podkrepljen opis izvajanja najpomembnejših funkcij za prenos podatkov.The diploma thesis contains presentation of LIN communication and description of used hardware. A developed software was written for LIN communication between two electronic circuits based on Microchip 18F microprocessors. A descriptions of settings, saved in two-dimensional arrays, types of settings modes, lists of all required files, libraries,… are also included. At the end, flowcharts of most important functions for LIN communication are presented
Domene (Macromene) jiangi Z. Peng
Domene (Macromene) jiangi Z. Peng and L.-Z. Li, 2017 Material studied. CHINA: Guangdong: 5 ♂♂, 4 ♀♀, Yingde, Shimentai, nr., Hengshitang, 24°24’22.6’’N, 113°18’24.6’’E, 180–700 m, 07.V.2021, Hu, Lin, Zhou & Li leg.” (SNUC); 5 ♂♂, 5 ♀♀, same data, but 150– 330 m. (SNUC). Comment. Domene jiangi was previously known from the Chinese provinces Guangxi (Peng et al. 2017). The above record from Guangdong represents a new province record. For illustrations of D. jiangi see Peng et al. (2017: figures 2, 3).Published as part of Lin, Xiao-Bin & Peng, Zhong, 2021, Two new species and additional records of mainland Chinese Domene (Coleoptera: Staphylinidae: Paederinae), pp. 444-450 in Zootaxa 5081 (3) on page 449, DOI: 10.11646/zootaxa.5081.3.8, http://zenodo.org/record/577584
Effects of adding nano metal powers on thermooxidative degradation of poly(Ethylene Glycol).
Z. Lin, X. Han, T. Wang and S. L
The Benefits of Being Economics Professor A (and not Z)
Alphabetic name ordering on multi-authored academic papers, which is the convention in the economics discipline and various other disciplines, is to the advantage of people whose last name initials are placed early in the alphabet. As it turns out, Professor A, who has been a first author more often than Professor Z, will have published more articles and experienced afaster growth rate over the course of her career as a result of reputation and visibility. Moreover, authors know that name ordering matters and indeed take ordering seriously: Several characteristics of an author group composition determine the decision to deviate from the default alphabetic name order to a significant extent.performance measurement, incentives, economists, name ordering
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