1,001 research outputs found

    sj-docx-1-tag-10.1177_17562848211066206 – Supplemental material for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy

    No full text
    Supplemental material, sj-docx-1-tag-10.1177_17562848211066206 for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy by Jianhong Peng, Yujun Liu, Weihao Li, Yuzhu Lin, Hui Sun, Zhizhong Pan, Xiaojun Wu, Wenhua Fan and Junzhong Lin in Therapeutic Advances in Gastroenterology</p

    sj-tif-3-tag-10.1177_17562848211066206 – Supplemental material for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy

    No full text
    Supplemental material, sj-tif-3-tag-10.1177_17562848211066206 for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy by Jianhong Peng, Yujun Liu, Weihao Li, Yuzhu Lin, Hui Sun, Zhizhong Pan, Xiaojun Wu, Wenhua Fan and Junzhong Lin in Therapeutic Advances in Gastroenterology</p

    sj-tif-4-tag-10.1177_17562848211066206 – Supplemental material for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy

    No full text
    Supplemental material, sj-tif-4-tag-10.1177_17562848211066206 for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy by Jianhong Peng, Yujun Liu, Weihao Li, Yuzhu Lin, Hui Sun, Zhizhong Pan, Xiaojun Wu, Wenhua Fan and Junzhong Lin in Therapeutic Advances in Gastroenterology</p

    sj-tif-2-tag-10.1177_17562848211066206 – Supplemental material for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy

    No full text
    Supplemental material, sj-tif-2-tag-10.1177_17562848211066206 for Application of Tumor Burden Score for predicting conversion outcome in patients with initially unresectable colorectal liver metastases after first-line systemic therapy by Jianhong Peng, Yujun Liu, Weihao Li, Yuzhu Lin, Hui Sun, Zhizhong Pan, Xiaojun Wu, Wenhua Fan and Junzhong Lin in Therapeutic Advances in Gastroenterology</p

    Topics in high-dimensional inference:

    No full text
    This thesis concerns three connected problems in high-dimensional inference: compound estimation of normal means, nonparametric regression and penalization method for variable selection. In the first part of the thesis, we propose a general maximum likelihood empirical Bayes (GMLEB) method for the compound estimation of normal means. We prove that under mild moment conditions on the unknown means, the GMLEB enjoys the adaptive ration optimality and adaptive minimaxity. Simulation experiments demonstrate that the GMLEB outperforms the James-Stein and several state-of-the-art threshold estimators in a wide range of settings. In the second part, we explore the GMLEB wavelet method for nonparametric regression. We show that the estimator is adaptive minimax in all Besov balls. Simulation experiments on the standard test functions demonstrate that the GMLEB outperforms several threshold estimators with moderate and large samples. Applications to high-throughput screening (HTS) data are used to show the excellent performance of the approach. In the third part, we develop a generalized penalized linear unbiased selection (GPLUS) algorithm to compute the solution paths of concave-penalized negative log-likelihood for generalized linear model. We implement the smoothly clipped absolute deviation (SCAD) and minimax concave (MC) penalties in our simulation study to demonstrate the feasibility of the proposed algorithm and their superior selection accuracy compared with the ell_1 penalty.Ph.D.Includes bibliographical references (p. 117-122)by Wenhua Jian

    Cultural identities as reflected in the literature of the Northern and Southern dynasties period (4th-6th centuries A.D.)

    No full text
    During the period of the Northern and Southern dynasties of China identity questions became serious in a society thrown into disorder by political, religious and ethnic problems. This thesis uses three books written in the sixth century to discuss how educated Chinese faced identity problems and how they dealt with them. The Buddhist monk Huijiao, dealt with the problems of sinifying a foreign religion. He constructed many different identities in addition to the Buddhist one for the monks in his book Gaoseng zhuan, (Lives of Eminent Monks), a collection of biographies of Buddhist monks, to bring Buddhism closer to Chinese tradition and more acceptable by Confucian standards. Through the identity construction he also made responses to anti-Buddhist ideas. Yang Xuanzhi's Luoyang qielan ji, (Record of the Monasteries of Luoyang), deals with the identity problems of Chinese officials serving a Xianbei regime in the north and of the short-lived capital of the Northern Wei in Luoyang. Yang reconstructed a Chinese identity for the lost capital as a true heir of Chinese tradition, as were the emperors, princes and officials who lived there. He created an identity defined not by ethnicity but by culture. Yan Zhitui's Tanshi jiaxun, (Family Instruction of the Yan Clan), is a book which tells his descendants how to construct and maintain the future identity of his own family. He drew on his own experience of recovering from repeated political catastrophes to set out an identity that would help the family to survive disordered times and maintain their status in society

    Wang Shuo and the commercialisation of contemporary Chinese culture

    No full text
    This thesis examines the commercialisation of Chinese culture that has taken place over the past twenty years in mainland China. It explores the contribution of Wang Shuo, a cultural figure who straddles different fields of culture, moving from literature to the ultimate mass culture medium of television, this study plots Wang Shuo' s development from educational failure, to business failure, to fiction writer, film &amp; TV editor, film director and cultural critic and analyst. His stories, films, TV series and articles have caused shock-waves throughout national cultural circles as he has transformed the terms of the debate from academic discourse to a validation of the role of the market in the culture field. Although Wang Shuo has not been labelled as a dissident, his approach to the culture market has had a more subversive effect on official ideology that those overt dissidents who have had to live in exile or have been imprisoned. He has utilised the language of official ideology to satirise the authorities, turning the ideology and its supporters into figures of fun. Yet his own goals have been strictly personal and economic ones. The authorities recognize the value of Wang Shuo's work in the cultural market but at the same time distrust his works and place him under strict censorship. Examining the way Wang Shuo and people surround him have succeeded in different fields of cultural achievement is a mirror to understanding the process of the transformation of contemporary Chinese culture from a socialist state-controlled culture to a market-oriented mass culture industry

    sj-docx-1-tam-10.1177_17588359231220607 – Supplemental material for Circulating tumor DNA analysis predicts recurrence and avoids unnecessary adjuvant chemotherapy in I–IV colorectal cancer

    No full text
    Supplemental material, sj-docx-1-tam-10.1177_17588359231220607 for Circulating tumor DNA analysis predicts recurrence and avoids unnecessary adjuvant chemotherapy in I–IV colorectal cancer by Wenhua Fan, Zhiyuan Xia, Rongrong Chen, Dagui Lin, Fang Li, Yang Zheng, Jiongyong Luo, Yuanyuan Xiong, Pengli Yu, Wei Gao, Yuhua Gong, Feiran Zhang, Sen Zhang and Liren Li in Therapeutic Advances in Medical Oncology</p

    sj-jpg-2-tam-10.1177_17588359231220607 – Supplemental material for Circulating tumor DNA analysis predicts recurrence and avoids unnecessary adjuvant chemotherapy in I–IV colorectal cancer

    No full text
    Supplemental material, sj-jpg-2-tam-10.1177_17588359231220607 for Circulating tumor DNA analysis predicts recurrence and avoids unnecessary adjuvant chemotherapy in I–IV colorectal cancer by Wenhua Fan, Zhiyuan Xia, Rongrong Chen, Dagui Lin, Fang Li, Yang Zheng, Jiongyong Luo, Yuanyuan Xiong, Pengli Yu, Wei Gao, Yuhua Gong, Feiran Zhang, Sen Zhang and Liren Li in Therapeutic Advances in Medical Oncology</p

    CUHK electronic theses & dissertations collection

    No full text
    Lin, Wenhua.Thesis (Ph.D.)--Chinese University of Hong Kong, 2011.Includes bibliographical references (leaves 162-190).Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.Abstract also in Chinese
    corecore