15,368 research outputs found
Preprocedure coagulation tests are unnecessary before abdominal paracentesis in Emergency Departments.
No full textExpression patterns of transforming growth factor-beta and its receptors in the gastric mucosa of patients with refractory gastric ulcer.
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Effects of a repetitive foot stepping exercise on proprioception and function in patients with knee osteoarthritis
No full textlin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulva development
No full textLate events in the cell-cell signalling pathway that controls the specification of vulva cell fates in C. elegans are characterized. The lin-31 gene acts downstream of the ras homolog let-60 and encodes a member of the HNF-3/fork head family of DNA-binding transcription factors. lin-31 regulates how vulval precursor cells choose their fate and in lin-31 mutants, these cells do not properly choose which fate to express and therefore adopt any of the 3 possible vulval cell fates in a deregulated manner..RE: 68 ref.; SC: CA; PE; 0TSource type: Electronic(1) http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0890-9369&isbn=&volume=7&issue=6&spage=933&pages=933-947&date=1993&title=Genes%20and%20Development&atitle=lin-31%2c%20a%20Caenorhabditis%20elegans%20HNF-3%2ffork%20head%20transcription%20factor%20homolog%2c%20specifies%20three%20alternative%20cell%20fates%20in%20vulva%20development.&aulast=Miller&pid=%3Cauthor%3EMiller%2c%20L%20M%3bGallegos%2c%20M%20E%3bMorisseau%2c%20B%20A%3bKim%2c%20S%20K%3C%2Fauthor%3E%3CAN%3E19932337278%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3
SC author and illustrator Kate Salley Palmer signing book
No full textPhotograph of SC author and illustrator Kate Salley Palmer signing boo
Silicon-germanium spherical quantum dot infrared photodetectors prepared by the combination of bottom-up and top-down technologies
No full textThe telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation
No full textBook signing by SC author and illustrator Kate Salley Palmer
No full textPhotograph of Book signing by SC author and illustrator Kate Salley Palme
Only full length mutp53 proteins exhibit strong SCS-binding in sc/lin competition assay for scBSK <i>in vitro</i>.
No full text<p>A) All mutp53fl proteins selectively recognized scBSK by EMSA. P53 proteins (protein amount expressed as p53/total DNA ratio) were incubated with scBSK (200 ng, lanes 1, 3–25) and linBSK (200 ng, lanes 2–25) and separated on a 1.3% 0.33x TBE agarose gel at 4°C (linDNA migrated faster than scDNA). P53-DNA binding was detected by Et-Br staining of DNA. The conformation of p53 proteins is labeled: white (wtp53), grey (conformation mutants) and black (contact mutants). B) Binding of CΔ30-wtp53 (lanes 4–7), CΔ30-G245S (lanes 8–11), CΔ30-R248W (lanes 12–15) and CΔ30-R175H (lanes 16–19) to pBSK in sc/lin competition asssay was performed similarly to p53fl (A). CΔ30-R248W and CΔ30-R175H lose the ability for strong SCS-binding. Column graph below was plotted on the basis of Et-Br stained DNA on agarose gels (from three independent experiments), free DNA substrates labeled with arrows were measured by densitometry and % of bound DNAs (sc and lin) were calculated the same way as in Fig. 2. C) Preferential binding of CΔ30-wtp53 (lanes 2–4) to linPGM1 in sc/lin competition assay with scBSK, complex of p53-linDNA is bonded.</p
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