3,062 research outputs found
A Near-optimal Sensor Placement Algorithm to Achieve Complete Coverage/Discrimination in Sensor Networks
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Energy-Efficient Sensor Network Design Subject to Complete Coverage and Discrimination Constraints
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An Investigation of Unbalanced-Magnetron Sputtered TiAlN Films on SKH51 High-Speed Steel
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COCAINE ELICITS ACTION POTENTIAL BURSTS IN A CENTRAL SNAIL NEURON: THE ROLE OF DELAYED RECTIFYING K CURRENT
No full textneuron of the African snail, Achatina fulica Ferussac, using the two-electrode voltage-clamp method. The RP4 neuron generated spontaneous action potentials & bath application of cocaine (0.3-1 mM) reversibly elicited action potential bursts of the central RP4 neuron in a concentrationdependent manner. The action potential bursts were not blocked when neurons were immersed in high-Mg2-solution, Ca2+-free solution, nor after continuous perfusion with atropine, d-tubocurarine, propranolol, prazosin, haloperidol, or sulpiride. Similarly, the action potential bursts were not abolished by pretreatment with N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride, (9S,10S,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1Hdiindolo[1,2,3-fg:3=,2=,1=-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid hexyl ester or anisomycin. Injection of hyperpolarizing current at an intensity of greater than 2 nA effectively suppressed the cocaine-elicited action potential bursts & no postsynaptic potentials were observed under these conditions. These results suggest that the generation of action potential bursts elicited by cocaine was not due to (1) the synaptic effects of neurotransmitters, (2) the cholinergic, adrenergic or dopaminergic receptors of the excitable membrane, or (3) the cAMP second messengers & new protein synthesis of the RP4 neuron. Notably, the induction of action potential bursts was blocked by pretreatment with 1-[6-[((17 )-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-1H-pyrrole-2,5- dione. Voltage-clamp studies conducted on the RP4 neuron revealed that cocaine at 0.3 mM decreased (1) the Ca2+ current, (2) the delayed rectifying K+ current, (3) the fast+inactivating K current & (4) the Ca2+-activated K+ current, but had no remarkable effects on the Na+ current. Perfusion with Ca2+-free solution, which may abolish the Ca2+ current & Ca2+ activated K+ current, did not cause any bursts of action potentials in control RP4 neurons
A Near-Optimal Sensor Placement Algorithm to Achieve Complete Coverage/Discrimination in Sensor Networks
No full textIn this letter, we develop a robust and scalable
algorithm to cope with the sensor placement problem for target
location under constraints of the cost limitation and the complete
coverage. The problem is NP-complete for arbitrary sensor fields.
The grid-based placement scenario is adopted and the sensor
placement problem formulated as a combinatorial optimization
problem for minimizing the maximum distance error in a sensor
field under the constraints. The proposed algorithm is based
on the simulated annealing approach. The experimental results
reveal that, for small sensor fields, the algorithm can find the
optimal sensor placement under the minimum cost limitation.
Moreover, it can also find a placement with minimum distance
error for large sensor fields under the cost limitation
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