348 research outputs found
Study on Disaster Controlling for Water Contamination of Severe Cr-contaminated Sites on Jialing River
No full textAbstractA severe Cr-contaminated site was left after the demolition of a Chemical plant. Based on the preliminary monitoring results and related literature data, this paper studied how to prevent and control the possible contamination from the site to Jialing River effectively, which is building an intercept contamination dam in the side of the contaminated site along Jialing River and constructing leachate collection system in the site. This is the antifouling effect: in the same stratum of the same elevation, the Cr6+content inside the intercept contamination dam (soil:144.8mg/kg∼827.4mg/kg, leaching solution: 7.3mg/L∼55.1mg/L) is higher than that of the outside (soil:10.4mg/kg∼64.9mg/kg, leaching solution: 0.27mg/L∼0.63mg/L); Water level of monitoring hole inside the dam is higher than that of the outside; the water level difference is 3.26m to 5.39m. The disaster controlling for the site provides security for the later contamination remediation and the river environment protection
Submergence tolerance of <i>R</i>. <i>nutans</i> seeds after summer flooding in the riparian zone of Jialing river (mean±SE).
No full textSubmergence tolerance of R. nutans seeds after summer flooding in the riparian zone of Jialing river (mean±SE).</p
Mindfulness-based therapy improves brain functional network reconfiguration efficiency
No full textMindfulness-based interventions are showing increasing promise as a treatment for psychological disorders, with improvements in cognition and emotion regulation after intervention. Understanding the changes in functional brain activity and neural plasticity that underlie these benefits from mindfulness interventions is thus of interest in current neuroimaging research. Previous studies have found functional brain changes during resting and task states to be associated with mindfulness both cross-sectionally and longitudinally, particularly in the executive control, default mode and salience networks. However, limited research has combined information from rest and task to study mindfulness-related functional changes in the brain, particularly in the context of intervention studies with active controls. Recent work has found that the reconfiguration efficiency of brain activity patterns between rest and task states is behaviorally relevant in healthy young adults. Thus, we applied this measure to investigate how mindfulness intervention changed functional reconfiguration between rest and a breath-counting task in elderly participants with self-reported sleep difficulties. Improving on previous longitudinal designs, we compared the intervention effects of a mindfulness-based therapy to an active control (sleep hygiene) intervention. We found that mindfulness intervention improved self-reported mindfulness measures and brain functional reconfiguration efficiency in the executive control, default mode and salience networks, though the brain and behavioral changes were not associated with each other. Our findings suggest that neuroplasticity may be induced through regular mindfulness practice, thus bringing the intrinsic functional configuration in participants' brains closer to a state required for mindful awareness
REGULATION OF THE CELL DEATH SIGNALING PATHWAY IN ANDROGEN-INDEPENDENT PROSTATE CANCER CELLS
No full textProstate cancer is the 2nd leading cause of cancer death in American men, mainly due to therapy-resistance in the advanced stage, androgen-independent prostate cancer (AIPCa). One major defect is that the cancer cells are insensitive to apoptosis induced by androgen ablation, chemotherapy or radiation therapy. However, the underline molecular mechanism still remains unclear. In this thesis, we focused on cell death signaling regulation in the development of AIPCa cells. We first show that up-regulation of Bcl-2, an anti-apoptotic oncogene, is required for the transition of prostate cancer cells from an androgen-dependent to an androgen-independent growth stage. Knockdown Bcl-2 impairs the transition process and blocks androgen-independent prostate tumor formation in vivo. Second, we show that Androgen-receptor (AR), which is generally considered as a survival factor in prostate cancer, promotes stress-induced apoptosis in AIPCa cells. AR promotes apoptosis through augmenting the mitochondrial translocation of Bax, a pro-death family member of Bcl-2. Finally, we show that AR can execute both pro-death and pro-survival events in same AIPCa cells. The AR pro-survival role is transcription-dependent, while its pro-death activity is transcription-independent. Interestingly, the AR exerts both functions through regulating p21 and JNK signaling pathways. These findings will help us to understand the dynamic survival signaling process in the development and progression of AIPCa. The key molecules identified here also provides potential therapeutic targets for the treatment of prostate cancer.Ph.D. in Biology, May 201
Analysis of the rainfall and runoff temporal variation of Jialing River during 1955-2006
No full textSeeing is believing?
No full textThis photograph originally appeared in the 2014 Research student photography and image competition held to celebrate National Science Week (Aug 16-24). Blurb: Guizhou province is one of the biggest minority provinces in China, where there are numerous minority areas experiencing tourism development under the label of Pro-poor tourism (PPT). What we saw is prosperous tourism market in these destinations with PPT strategy guided by China government, but does this strategy really help poor people eliminate poverty or instead, enhance the polarization of wealth distribution and the loss of discourse space?
During my survey in Guizhou, I witnessed that poor people are still trying hard to be the beneficiaries of tourism development and they are unable to gain long-term benefits from PPT for the lack of essential skills, knowledge and capital. And it is worthy to note that irrational development of tourism has led to serious cultural changes among minority areas
Two new species of freshwater Macrostomum (Rhabditophora: Macrostomorpha) found in China
No full textThere is limited information about the ecology of freshwater flatworms in China, in particular, the members of the genus Macrostomum. Surveying freshwater bodies to explore the species diversity is the first step to obtain more ecological information about those flatworms. We hereby report the discovery of two new species of freshwater flatworms in Macrostomum. Macrostomum chongqingensis Lin and Wang, n. sp. was discovered from stones in the shallow water of Jialing River bed near Chongqing. Macrostomum zhaoqingensis Lin and Wang, n. sp. was discovered in the water of Xing Lake near Zhaoqing city, Guangdong province. Xing Lake is a part of an ancient river that has changed its course. For each species, we describe the morphology of the whole specimen, penis stylet, and sperm, as well as other internal anatomical features based on serial sections. We determined 18S, 28S rDNA and COI sequences from the two new species, and performed a phylogenetic analysis to confirm the status and evolutionary position of the two new species. We discuss the significance of our discoveries in terms of flatworm biodiversity studies in China and the Oriental realm. </jats:p
A prospective cohort study of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage in neonates: the role of maternal carriage and phenotypic and molecular characteristics
No full textJialing Lin,1 Chuanan Wu,2 Chunrong Yan,2 Qianting Ou,1 Dongxin Lin,1 Junli Zhou,1 Xiaohua Ye,1 Zhenjiang Yao1 1Department of Epidemiology and Health Statistics, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China; 2Maternal and Child Health Care Center of Longhua District, Shenzhen, China Background: Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA), in mothers can cause serious outcomes in neonates. We aimed to elucidate the associations of S. aureus and MRSA carriage between mothers and neonates. Methods: A prospective cohort study was conducted between August and November 2015 in two hospitals in Shenzhen, China. Chinese pregnant women and their neonates who met the inclusion criteria were included in this study; samples and relevant information were collected. We assessed maternal–neonatal associations by using Poisson regression models. Results: Overall, 1834 mothers and their neonates were included in this study. The prevalence of isolate carriage among the mothers was as follows: S. aureus (nasal, 25.8%; vaginal, 7.3%; and nasal and vaginal, 3.3%) and MRSA (nasal, 5.7%; vaginal, 1.7%; and nasal and vaginal, 0.5%). The incidences of S. aureus and MRSA carriage among neonates were 3.3% and 0.8%, respectively. Of the 21 maternal–neonatal pairs with S. aureus carriage, 14 were concordant pairs with the same phenotypic and molecular characteristics. After adjustment, the relative risks and 95% confidence intervals (CIs) between the S. aureus carriage of neonates and nasal S. aureus carriage, vaginal S. aureus carriage, and both nasal and vaginal S. aureus carriage of mothers were 2.8 (95% CI, 1.6–4.8), 7.1 (95% CI, 4.1–12.4), and 9.6 (95% CI, 4.2–22.4), respectively. Conclusion: S. aureus carriage in mothers increases the risk for neonates. Keywords: Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, neonates, mothers, maternal–neonatal associatio
MyMedicare promises better health care. But only 1 in 10 patients has signed up
No full textMyMedicare is a scheme that encourages patients to register with a regular GP practice to improve their health. But few patients have enrolled.
Since its launch in October 2023, only about 10% of patients have signed up.
Read the full article on The Conversation:
https://theconversation.com/mymedicare-promises-better-health-care-but-only-1-in-10-patients-has-signed-up-25333
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