173,676 research outputs found
Are employees with higher organization-based self-esteem less likely to quit? A moderated mediation model
Full text linkCitation: Lin, N., Jang, J., & Roberts, K. R. (2018). Are employees with higher organization-based self-esteem less likely to quit? A moderated mediation model. International Journal of Hospitality Management, 73, 116–124. https://doi.org/10.1016/j.ijhm.2018.01.021This study focuses on striving for achievement as an important antecedent forming Organization-Based Self-Esteem (OBSE) and the relationship between achievement striving and turnover intention in the hospitality industry. More specifically, employees with higher achievement striving traits show a stronger negative correlation between OBSE and turnover intention, through organizational commitment. An online survey was distributed to restaurant employees; 160 valid responses were analyzed. An analytic framework based on confirmatory factor analysis and logic regression was used to examine the hypotheses. The results show that organizational commitment fully mediated the relationship between OBSE and turnover intention, and higher levels of individual achievement striving significantly modified the conditional indirect relationship. The results showed that the mediation model and achievement striving strength accounted for 15.7% of the variance in turnover intention at the 50?th, 75?th, and 90?th level and was most effective for low OBSE employees. Theoretical implications and future research are included
The results of Wei-Lin-Weissfeld (WLW) model for long-term global and event-specific outcomes.
No full textThe results of Wei-Lin-Weissfeld (WLW) model for long-term global and event-specific outcomes.</p
Figure 3 in DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract
No full textFigure 3. Wings of Dicrotendipes sinicus Lin & Qi sp. n. adults. A, brachypterous, oar-shaped wing of adult male; B, brachypterous, oar-shaped wing of adult female; C, fully developed wing of adult female. Scale bars = 100 µm. First published by Qi et al. (2018), Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).Published as part of Lin, Xiao-Long & Qi, Xin, 2021, DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract, pp. 21-32 in CHIRONOMUS Journal of Chironomidae Research 34 on page 25, DOI: 10.5324/cjcr.v0i34.4079, http://zenodo.org/record/799621
Figure 7 in DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract
No full textFigure 7. Adult female of Dicrotendipes sinicus Lin & Qi sp. n. A, thorax dorsal view, scale bar = 200 µm; B, abdo- men, scale bar = 500 µm; C, genitalia, scale bar = 200 µm. First published by Qi et al. (2018), Attribution-NonCom- mercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).Published as part of Lin, Xiao-Long & Qi, Xin, 2021, DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract, pp. 21-32 in CHIRONOMUS Journal of Chironomidae Research 34 on page 29, DOI: 10.5324/cjcr.v0i34.4079, http://zenodo.org/record/799621
Figure 1 in DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract
No full textFigure 1. Dicrotendipes sinicus Lin & Qi sp. n. in 85% ethanol. A, adults and a larva; B, adult male dorsal view; C-D, adult female dorsal view; E, larva lateral view. First published by Qi et al. (2018), Attribution-NonCommercial- NoDerivatives 4.0 International (CC BY-NC-ND 4.0).Published as part of Lin, Xiao-Long & Qi, Xin, 2021, DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract, pp. 21-32 in CHIRONOMUS Journal of Chironomidae Research 34 on page 23, DOI: 10.5324/cjcr.v0i34.4079, http://zenodo.org/record/799621
Figure 6 in DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract
No full textFigure 6. Adult male of Dicrotendipes sinicus Lin & Qi sp. n. A, antenna; B, thorax; C, hypopygium dorsal view; D, hypopygium ventral view; E, anal point lateral view; F, median volsella. First published by Qi et al. (2018), Attribution- NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).Published as part of Lin, Xiao-Long & Qi, Xin, 2021, DICROTENDIPES SINICUS LIN & QI, SP. N. (DIPTERA: CHIRONOMIDAE) Abstract, pp. 21-32 in CHIRONOMUS Journal of Chironomidae Research 34 on page 28, DOI: 10.5324/cjcr.v0i34.4079, http://zenodo.org/record/799621
Intestinal Lin(-)c-Kit(+)NKp46(-)CD4(-) Population Strongly Produces IL-22 upon IL-1 beta Stimulation
No full textSmall intestinal innate lymphoid cells (ILCs) regulate intestinal epithelial cell homeostasis and help to prevent pathogenic bacterial infections by producing IL-22. In a global gene-expression analysis comparing small intestinal ILCs (Lin(-)c-Kit(+)Sca-1(-) cells) with non-ILCs (Lin(-)c-Kit(-)Sca-1(-) cells), we found that Lin(-)c-Kit(+)Sca-1(-) cells highly expressed the mRNAs for Il22, antimicrobial peptides, Csf2rb2 (Il3r), mast cell proteases, and Rorc. We then subdivided the Lin(-)c-Kit(+)Sca-1(-) cells into three groups-Lin(-)c-Kit(+)NKp46(-)CD4(-), Lin(-)c-Kit(+)NKp46(-)CD4(+) (CD4(+) LTi-like cells), and Lin(-)c-Kit(+)NKp46(+) (NKp46(+) ILC22 cells)-and showed that the Lin(-)c-Kit(+)NKp46(-)CD4(-) cells produced the highest level of IL-22 protein after IL-1 beta, IL-23, or IL-1 beta and IL-23 stimulation. In addition, we showed that the majority of the Lin(-)c-Kit(+)NKp46(-)CD4(-) population was IL-7R alpha(+)CD34(-)beta 7(int) cells, and IL-7R alpha(-) cells could be divided into three subsets (CD34(+)beta 7(int), CD34(-)beta 7(int), and CD34(int)beta 7(hi) cells). The IL-7R alpha(+)CD34(-)beta 7(int) cells strongly expressed the transcripts for Il17f and Il22 after costimulation with IL-1 beta and IL-23. The IL-7R alpha(-)CD34(+)beta 7(int) and IL-7R alpha(-)CD34(int)beta 7(hi) cells predominantly expressed the transcripts for mast cell proteases and differentiated almost entirely into mast cells after 1 wk in culture medium supplemented with a cytokine mixture, whereas the IL-7R alpha(-)CD34(+)beta 7(int) cells highly expressed alpha-defensins and showed no differentiation. Taken together, these findings indicate that the IL-7R alpha(-)CD34(+)beta 7(int) and IL-7R alpha(-)CD34(int)beta 7(hi) populations are mast cell progenitors, and the IL-7R alpha(-)CD34(-)beta 7(int) (CD4(-) LTi-like cells) and IL-7R alpha(-)CD34(-)beta 7(int) populations within Lin(-)c-Kit(+)NKp46(-)CD4(-) cells may control intestinal homeostasis and provide intestinal protection by producing high levels of IL-22 and alpha-defensins, respectively.
The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing
No full textLin-41 is a stem cell-specific E3 ligase and a known target of the tumour suppressor microRNA (miRNA) let-7. Lin-41 was recently reported to mediate ubiquitylation and degradation of the miRNA pathway protein Ago2. We demonstrate that Lin-41 is over-expressed in hepatocellular carcinoma (HCC). Lin-41 over-expression correlates with high a-fetoprotein level, high tumour grade and high tumour stage and predicts early tumour recurrence. Lin-41 is a strong predictor of poor long-term survival for patients with HCC. Lin-41 knock-down by RNA interference in HCC cell lines Huh7 and Hep3B suppressed proliferation in vitro and reduced in vivo tumour growth in NOD/SCID mice. On the other hand, over-expression of Lin-41 in the HCC cell line SK-Hep1 enhanced tumourigenicity. Over-expression and knock-down of Lin-41 led to inverse changes in the levels of Ago1 and Ago2 proteins. Over-expression of Ago1 and Ago2 reduced in vivo tumour growth. Lin-41 over-expression suppressed let-7 activity in HCC cell lines and expression of Lin-41 enhanced the expression of let-7-regulated oncogenes c-Myc, Lin-28B, HMGA2 and type 1 insulin-like growth factor receptor (IGF1R). Expression of Lin-28B and c-Myc enhanced the expression of Lin-41. Chromatin immunoprecipitation and reporter assays revealed direct association of c-Myc with the Lin-41 promoter, resulting in transcriptional transactivation. Our results indicate that Lin-41 plays an important role in the growth of HCC by regulating RISC complex proteins Ago1 and Ago2 to inhibit miRNA-mediated gene silencing and promote the expression of oncogenic proteins. Lin-41 is also a strong prognostic factor for patients with HCC. Copyright (C) 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd
Spiniphilus spinicornis Lin & Bi 2011
No full textSpiniphilus spinicornis Lin & Bi, 2011 (Figs. 1 & 3) Spiniphilus spinicornis Lin & Bi, 2011: 55, figs. 1–2. Remarks. There is a mistake in Lin & Bi (2011). Fig. 9 a is dorsal view while Fig. 9 b is ventral view. Distribution. China: Yunnan. Material examined. Holotype (26.0 mm long), male, China, Yunnan Prov., Yingjiang (24 ° 46 ′N, 97 ° 58 ′E), 1700 m, 1980. IV. 15, leg. Ping Gao (IZAS, IOZ (E) 1859320). Paratypes: 1 female (37.0 mm long), same data as holotype but 1980. IV. 21, IOZ (E) 1859322; 2 males, Yunnan prov., Tengchong County, Longchuanjiang (24 ° 55 ′N, 98 ° 42 ′E), alt. 1050 m, 2006. V. 16, leg. Ping Zhao by light trap (IZAS, IOZ (E) 1859321 & CCCC). Additional material. 2 males, Yunnan, Tengchong County, Mt. Laifengshan (25.019 °N, 98.485 °E), alt. 1700 m, 2011. V. 6, leg. Wan-Gang Liu (IZAS, specimens in alcohol, with one male sent to Petr Švácha for molecular study).Published as part of Bi, Wenxuan & Lin, Meiying, 2015, Discovery of second new species of the genus Spiniphilus Lin & Bi, and female of Heterophilus scabricollis Pu with its biological notes (Coleoptera: Vesperidae: Philinae: Philini), pp. 575-583 in Zootaxa 3949 (4) on page 576, DOI: 10.11646/zootaxa.3949.4.7, http://zenodo.org/record/24151
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