11,115 research outputs found
Frank Swinnerton : the life and works of a bookman
No full textFrank Swinnerton worked as a clerk for J.M. Dent & Co. between 1901 and 1907 and as a publisher's reader for Chatto & Windus from 1907 until 1926, during which time he began his career as a writer of fiction, became influential as a reviewer and commentator on literary fashions, and began close friendships with Arnold Bennett, HG Wells and Hugh Walpole. In 1926 he left London to live in Cranleigh, Surrey, as a full-time writer of novels, short stories, critical works, book and theatre reviews, and miscellaneous articles for newspapers and periodicals. He died at the age of ninety-eight in 1982. This is the first biography of Frank Swinnerton to be undertaken in Great Britain. An analysis has been made of each of his works, both novels and non-fiction. His influence in literary circles has been assessed, and his contribution to the book world is placed within the background of literary output and trends in the twentieth century. Swinnerton was not a great writer, but his temperament, circumstances and talent combined to produce a respected literary figure whose strength was his perception and understanding of the progress of the British literary world through the centuries.
Swinnerton's numerous friendships are dealt with as they occurred, although major relationships are examined more fully at the point where the friend died. For example, details on HG Wells can be found with his death in 1946 and on Compton Mackenzie with his death in 1972. Greater space has been given to his involvements with Arnold Bennett and Hugh Walpole, in separate chapters placed close to the time of their deaths in 1931 and 1941. One other chapter stands out of sequence. This examines Swinnerton's relationship with his two wives: his complex courtship of Helen Dircks and his second marriage to Mary Bennett. This period, between 1917 and 1924, which also includes a
description of his first lecture tour of the USA in 1923, has been placed immediately after chapters 7 and 8, which examine Swinnerton's general life and work during the same period. Apart from published works and newspaper and periodical articles, the main material used has been Swinnerton's personal diaries, which date from 1910 to 1978, and the correspondence and miscellaneous papers in his personal possession. Also consulted has been a doctoral thesis by Jesse Franklin McCartney presented to the University of Arkansas in 1965, which annotates the large collection of correspondence by Frank Swinnerton to writers, publishers, boakmen and other literary figures, as well as their
replies, which are housed in the University library. Full texts of these letters have been obtained where appropriate and used in this work. Professor Blair Rouse of the University of Arkansas wrote a critical appreciation of Swinnerton's work in the 1960s and his widow has allowed use of the unpublished manuscript and letters exchanged between Rouse and Swinnerton, and has sent correspondence between Swinnerton and the Pinker family. Finally, Swinnerton's friends and family have provided facts, opinions and reminiscences
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lin-4 and the NRDE pathway are required to activate a transgenic lin-4 reporter but not the endogenous lin-4 locus in C. elegans.
No full textAs the founding member of the microRNA (miRNA) gene family, insights into lin-4 regulation and function have laid a conceptual foundation for countless miRNA-related studies that followed. We previously showed that a transcriptional lin-4 reporter in C. elegans was positively regulated by a lin-4-complementary element (LCE), and by lin-4 itself. In this study, we sought to (1) identify additional factors required for lin-4 reporter expression, and (2) validate the endogenous relevance of a potential positive autoregulatory mechanism of lin-4 expression. We report that all four core nuclear RNAi factors (nrde-1, nrde-2, nrde-3 and nrde-4), positively regulate lin-4 reporter expression. In contrast, endogenous lin-4 levels were largely unaffected in nrde-2;nrde-3 mutants. Further, an endogenous LCE deletion generated by CRISPR-Cas9 revealed that the LCE was also not necessary for the activity of the endogenous lin-4 promoter. Finally, mutations in mature lin-4 did not reduce primary lin-4 transcript levels. Taken together, these data indicate that under growth conditions that reveal effects at the transgenic locus, a direct, positive autoregulatory mechanism of lin-4 expression does not occur in the context of the endogenous lin-4 locus
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Letter from Unknown to William C. Brice, February 18, 1963
No full textUnknown author (Frank ??) proposes to Brice a number of changes to his upcoming article in Kadmos concerning ideographic and phonetic scripts.Classic
Frank C. Cummings, circa 1978
No full textFrank C. Cummings with a minister seated at a table.The Atlanta University Center Robert W. Woodruff Library acknowledges the generous support of the National Endowment for Humanities - Humanities Collections and Reference Resources Implementation Project Grant in supporting the processing and digitization of a number of its major archival collections as part of the project: Spreading the Word: Expanding Access to African American Religious Archival Collections at the Atlanta University Center Robert W. Woodruff Library.</em
Supplementary Figure S6 in Mitogenomic phylogeny of the Asian colobine genus Trachypithecus with special focus on Trachypithecus phayrei (Blyth, 1847) and description of a new species
No full textSupplementary Figure S6 Ventral view of skull without mandible (A), and dorsal (B), lateral (C), and ventral (D) views of mandible of holotype (NHMUK ZD.1914.7.19.3) of Trachypithecus popa sp. nov. (Photo: Courtesy of the Trustees of the Natural History Museum, London).Published as part of Roos, Christian, M. Helgen, Kristofer, Portela Miguez, Roberto, May Lay Thant, Naw, Lwin, Ngwe, Ko Lin, Aung, Lin, Aung, Mar Yi, Khin, Soe, Paing, Mar Hein, Zin, Nyein Nyein Myint, Margaret, Ahmed, Tanvir, Chetry, Dilip, Urh, Melina, Grace Veatch, E., Duncan, Neil, Kamminga, Pepijn, A. H. Chua, Marcus, Yao, Lu, Matauschek, Christian, Meyer, Dirk, Liu, Zhi-Jin, Li, Ming, Nadler, Tilo, Fan, Peng-Fei, Khac Quyet, Le, Hofreiter, Michael, Zinner, Dietmar & Momberg, Frank, 2020, Mitogenomic phylogeny of the Asian colobine genus Trachypithecus with special focus on Trachypithecus phayrei (Blyth, 1847) and description of a new species, pp. 656-669 in Zoological Research 41 (6) on page 676, DOI: 10.24272/j.issn.2095-8137.2020.254, http://zenodo.org/record/439589
Frank Zhang: Hipster Extraordinaire
No full textAfter the delicate deliberation of the characters of the series Heroes of Olympus by Rick Riordan, it was decided by both writers that Frank Zhang, son of Mars, is the ultimate hipster demigod. The structure of this essay was based on a simple argument, and carefully dissects the full series in order to really convey who Frank Zhang really is. It was additionally concluded by both writers that as complicated and intricate a character as Frank Zhang is, we wanted the audience to be able to not only imagine the illustrations of the character, but to further empathize with the character\u27s emotions. Through the attendance of two separate classes, a review from the professor, and careful editing, the essay comes to a complete conclusion demonstrating our perspective on the author\u27s ultimate purpose
Scientific Principles of Gymnastic Coaching (c. 1967-1968)
No full textThis is a two page document that lists ten scientific principles of gymnastic coaching, likely produced during the 1967-1968 academic year. The principles covered are center of gravity, equilibrium, strength, timing, acceleration and deceleration of angular velocity, diminishing the force of a fall, momentum, and newton’s laws. The author is not known. The document is part of the Frank Wolcott papers.For biographical information on Frank Wolcott, see: https://springfield.as.atlas-sys.com/agents/people/54
Thr-96 is the major phosphorylation site in LIN-9 for Cdk3/cyclin E1.
No full text<p>Indicated GST-LIN-9 deletion constructs were expressed in bacteria, purified, and subjected to in vitro kinase assays using Flag-IPs from 293T cells cotransfected with Flag-Cdk3 and untagged cyclin E1. Autoradiogram shows phosphorylation of recombinant LIN-9 proteins (upper panel). CBB staining of the same gel was used to visualize the amounts of GST-LIN-9 constructs in the reaction (lower panel) Asterisks indicate the respective GST-LIN-9 constructs. (B) Indicated GST-LIN-9 full-length mutants expressed in bacteria were subjected to in vitro kinase assays using Flag-Cdk3/cyclin E precipitated from 293T cells, transfected with FLAG-Cdk3 and cyclin E1, via Flag-antibody as a kinase. LIN-9 phosphorylation (upper panel), Flag-Cdk3 and cyclin E1 autophosphorylation (middle panel) were monitored by autoradiography. Loading of GST-LIN-9 mutants was determined by CBB staining of the same gel (lower panel). (C) GST-LIN-9-1-109 and its mutants (S76A and T96A) were subjected to kinase assays as in B. GST-LIN-9 phosphorylation was again detected by autoradiography (upper panel) and equal loading was confirmed by CBB staining of the same gel (lower panel). (D) Alignment of LIN-9 amino acid residues surrounding Thr-96 among species. Identical residues are depicted in red, strongly similar residues are depicted in green, and non-similar residues are depicted in blue. Arrow indicates position of Thr-96. Accession numbers of aligned amino acid sequences are: Homo sapiens: AAV41873.1; Mus musculus: NP_001096652.1; Xenopus laevis: NP_001121233.1 and Danio rerio: NP_001038411.1.</p
Oxidation of organic pollutants over MnO2 in cold water assisted by peroxydisulfate
No full textMnO2 can be used in advanced oxidation processes to activate peroxydisulfate (PS) and generate reactive species such as sulfate radicals (SO4 center dot-), hydroxyl radicals (center dot OH) and singlet oxygen (1O2) for the abatement of organic water contaminants. Alternatively, one can use MnO2 as particulate oxidant which, in contrast to PS, is active already at low temperatures. This low-temperature activity is particularly attractive for in situ groundwater treatment. The roles of PS and MnO2 as oxidant and catalyst, respectively, may invert: MnO2 functions as primary oxidant and PS works as re-oxidant of reduced Mn-oxides. In this way, the limited oxidation capacity of particulate MnO2 can be overcome. So far, such reaction systems have not been extensively explored.In the present study, the degradation of 4-hydroxybenzoic acid (HBA) by PS + MnO2 was studied under various experimental conditions, by varying reaction temperature (15-45 degrees C), reagent concentrations, and water matrix. Both PS and MnO2 alone have the ability to effect the oxidation of HBA. In the co-presence of PS and MnO2, a fast removal of HBA from water was achieved even at low temperatures (half-life of HBA about 0.5 h with 2.4 g L-1 MnO2 at 25 degrees C), owing to a synergic effect between the two components.Quenching experiments indicate that the primary HBA oxidation step is a heterogeneous reaction on the MnO2 surface rather than a homogeneous reaction driven by SO4 center dot-or 1O2, as frequently reported in literature. This is in line with results from the PS driven oxidation of perfluorooctanoic acid which is not significantly enhanced in the presence of MnO2
Lately at the Library: Frank Williams Interviews William C. Davis
No full textJustice Frank Williams, president of the Ulysses S. Grant Presidential Library and Association, interviews publisher and author, William C. Davis, the third lecturer for the Frank and Virginia Williams Lecture Series. In the interview, Mr. Davis discusses how he got his start in the publishing industry, how he and Frank Williams first became friends, his twenty year career in the publishing industry and his career as an editorial vice president of publishing for over 30 magazines, his time spent as an editor of the Civil War Times and an anecdote on how the Civil War Times got it\u27s start as a magazine. Davis goes on to discuss his current book and how he chose the topic of Jefferson Davis in comparison to Abraham Lincoln, the differing strategies of General Grant and General Lee and how that worked in Grant\u27s favor as a later president, the toll the war took on Abraham Lincoln and how connected he was with his people versus how dry and unbeloved Jefferson Davis was. He describes Jefferson Davis\u27s childhood and personal life and how it affected him as a person and a leader. The interview concludes with Mr. Davis\u27s take on the current issue of confederate and other problematic statues in the United States
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