77,186 research outputs found
The immobilization of Chinese herbal medicine onto the surface-modified calcium hydrogenphosphate
To accelerate the healing of bone defects or to enable to heal at all, it is often
necessary to fill them with suitable substance. Various artificial materials defects have
been developed. Among these, calcium phosphates and bioactive glass have been
proven to be biocompatibile and bioactive materials that can chemically bond with
bone, and have been successfully used clinically for repair of bone defects and
augmentation of osseous tissue. However, those bioceramics have only the property of
osteoconduction without any osteoinduction.
Many ligands have been physicochemically absorbed onto substrates to enhance
cell-substrate interactions. Although it has been widely developed, it is still limited to
use in long-term implantation because of short half-life period. Thus, some interfacial
modification will be required for enhancing the efficacy of delivery system. These
models involve the immobilization of biologically active ligands of natural and
synthetic origin onto various substrates to produce an interface with stronger chemical
bond between ligand and substrate. The advantage of covalently immobilizing a
ligand is that a chemical bond is present to prevent ligand or medicine from
desorption.
In our study, two-step of chemical immobilization was performed to
surface-modified calcium hydrogenphosphate powders. The first was to modify the
surface of calcium hydrogen-phosphate (CHP) with coupling agent of
hexanmethylene diisocyanate (HMDI). The linkage between CHP and HMDI will be
characterized by FTIR. The second step was to immobilize chemically Gusuibu onto
MCHP. Moreover, the sorption and desorption of Gusuibu was evaluated and
quantitative analyzed by spectrophotometer and HPLC.
From the results, bioceramic CHP was surface-modified by two-step of chemical
immobilization. Firstly, successfully modified the surface of calcium
hydrogen-phosphate (CHP) with coupling agent of hexanmethylene diisocyanate
(HMDI). The first step was also activated the surface of CHP to induce primary amine
terminator. The reaction of this functional group with Gusuibu was the second step.
We confirmed simultaneously that Gusuibu could be immobilized chemically onto the
surface of MCHP. Although some immobilized Gusuibu also released rapidly at the
first 12 hours, the degree of released Gusuibu was lower than both by
Gusuibu-adsorbing MCHP and Gusuibu-adsorbing CHP
Ming maritime governance and the Suppression of Lin Feng
Piracy in Ming China during the 1560s and 1570s, while not frequently discussed, posed a unique maritime problem for officials to tackle. One threat they faced in this period was Lin Feng (active 1568–1580s), a pirate appearing on the coasts of Guangdong and Fujian provinces since the early Longqing period (1567–1572). Lin Feng was constantly seen clashing with the Ming military and had considerable influence; in 1574, he even sailed to Luzon, part of the modern-day Philippines, and appointed himself as the lord there. Eventually, he was evicted back to the Ming coasts, where the military suppressed his forces in 1576, early in the reign of the Wanli emperor (1572–1620). Previous scholars have noted Lin Feng’s trans-local impacts and portrayed him as a cultural broker between imperial China and the Philippines. What they neglected to do, however, was treat the conflicts and encounters he shared with officials as instances of Ming maritime governance.
To revisit the case of Lin Feng from a political perspective, this thesis uses records from gazetteers, Ming shilu, memorials, legal codes, and letters. It places him with Longqing and Wanli officials to trace the complex processes through which officials reached their decisions. This thesis presents four seemingly separate incidents involving Lin Feng and various Ming officials that became the milestones of the Suppression of Lin Feng, the campaign to eliminate his forces. Each of the officials discussed in these examples came from diverse backgrounds with varying levels of prestige. Yet they were all, as this thesis argues, motivated by two kinds of factors interwoven with each other: structural—the broader political, geographic, social, and economic contexts as well as the experience of their predecessors—and personal—opportunities to keep their careers or elevate their statuses while gaining material benefits. Making this argument can help this thesis highlight the paramount roles that officials played in this campaign and, in doing so, offer new understandings of Lin Feng as a historical character and position county and provincial-level officials as being integral to creating and enforcing policies for Ming maritime governance.Arts, Faculty ofHistory, Department ofGraduat
The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways
Copyright © 2009 Elsevier Ltd All rights reserved.Mei-Chi Chang, Li-Deh Lin, Chiu-Po Chan, Hsiao-Hua Chang, Lin-I. Chen, Hsueh-Jen Lin, Hung-Wei Yeh, Wan-Yu Tseng, Po-Shuen Lin, Chiu-Chun Lin and Jiiang-Huei Jenghttp://www.elsevier.com/wps/find/journaldescription.cws_home/30392/description#descriptio
Words & Music-Lin Hsiu huei CLTA meeting
Electronic reproduction from Rulan Chao Pian Manuscript Collection
Dataset for Single-Shot Phase and Amplitude Fluctuations of Narrow-Line Pulse Bursts in Divided-Pulse Amplifier
This dataset supports the article Lin, H., Feng, Y., Price, J., & Nilsson, J. (2019). Single-shot phase and amplitude fluctuations of narrow-linewidth pulse bursts in divided pulse amplifier. IEEE Photonics Technology Letters, 31(20), 1662 - 1665. DOI: 10.1109/LPT.2019.2942175</span
Chinese language samples (6), letter by Chin Feng Lin
A sample of Chinese language writing, possibly a memento from the possessions of Susan Tallmon Sargent; this was a letter written by Chin Feng Li
- …
