482,701 research outputs found
Du lin sauvage au lin cultivé
No full textNational audienceLe lin actuellement cultivé correspond à l'espèce domestique (Linum usitatissimum L.) qui dérive de l'exploitation de l'ancêtre sauvage, le lin bisannuel ou lin à feuilles étroites (Linum bienne Mill.). L'adaptabilité du lin sauvage à différentes conditions environnementales permet d'expliquer sa large répartition géographique, du Caucase au Nord de l'Afrique et de la Méditerranée à l'Europe occidental
Lysmata bahia Rhyne & Lin 2006
No full textLysmata bahia Rhyne & Lin, 2006 (Figure 7F) Material examined. Penaeid—1 OF; CL: 9.4 mm; CZUFS CRU- 00317. Stations. Penaeid—4. Distribution. Western Atlantic—Panama (Bocas Del Toro), and Brazil (Ceará, Sergipe, Bahia, Rio de Janeiro, and São Paulo) (Rhyne & Lin 2006; Baeza 2008; Barros-Alves et al. 2015; Pachelle et al. 2016). Ecological notes. Found at 5 m depth, on non-consolidated bottoms, on reefs, and inside calcareous algae (Almeida et al. 2012). Remarks. Part of a monophyletic group composed of Lysmata gacilirostris Wicksten, L. pederseni Rhyne & Lin, L. ankeri Rhyne & Lin, L. nayaritensis Wiksten, L. californica (Stimpson), and L. bahia supported by phylogenetic analysis (Baeza 2010). Previous records in Sergipe. Barros-Alves et al. (2015).Published as part of Mendonça, Luana M. C., Guimarães, Carmen R. P., Santos, Rafael C., Alves, Douglas F. R., Barros-Alves, Samara P., Silva, Sonja L. R. & Hirose, Gustavo L., 2019, Decapod crustaceans from the continental shelf of Sergipe, northeastern Brazil, pp. 301-344 in Zootaxa 4712 (3) on page 330, DOI: 10.11646/zootaxa.4712.3.1, http://zenodo.org/record/358631
Hyllus C. L. Koch 1846
No full textGenus Hyllus C. L. Koch, 1846 Type species. Hyllus giganteus C. L. Koch, 1846 from Indonesia.Published as part of Lin, Yejie, Zhao, Huifeng, Koh, Joseph K H & Li, Shuqiang, 2022, Taxonomy notes on twenty-eight spider species (Arachnida: Araneae) from Asia, pp. 198-270 in Zoological Systematics 47 (3) on page 230, DOI: 10.11865/zs.2022303, http://zenodo.org/record/717585
A single E-box in the <i>Cel-lin-3</i> CRM is not sufficient for <i>lin-3</i> expression in the anchor cell of <i>C</i>. <i>elegans</i>.
No full text(A) New cis-regulatory lin-3 alleles with deleted E-boxL and NHR or NHR and E-boxR. (B) Quantification of vulval induction in these new mutants. Note the complete absence of any induction in the recovered lin-3 alleles (n>30). Scorings of lin-3(1417) animals are the same as those reported in Fig 5 and are used here to indicate that this mutation leads to vulval hypo-induction rather than no induction at all. (C-D) smFISH in lin-3(mf72) (C) and N2 (D) animals. Green spots correspond to lin-3 transcripts and red spots to lag-2 that is used as an anchor cell marker. Blue is DAPI staining of nuclei. Note the absence of lin-3 expression in the anchor cell in the lin-3(mf72) mutant animal. Absence of lin-3 signal in the anchor cell was also confirmed for the other lin-3 alleles.</p
Lysmata bahia Rhyne & Lin 2006
No full text<i>Lysmata bahia</i> Rhyne & Lin, 2006 <p> <i>Lysmata bahia</i> Rhyne & Lin, 2006: 191, figs. 16–18, pl. 1F.</p> <p> <b>Material examined.</b> None.</p> <p> <b>Distribution.</b> Western Atlantic—Panama and Brazil (Ceará, Sergipe, Bahia, Rio de Janeiro, São Paulo) (Rhyne & Lin 2006; Baeza 2008; Barros-Alves <i>et al</i>. 2015; Pachelle <i>et al</i>. 2016).</p> <p> <b>Previous records.</b> Santos Harbor (paratypes collected in 1950 and deposited at USNM) (Rhyne & Lin 2006).</p>Published as part of <i>Terossi, Mariana, Almeida, Alexandre O., Buranelli, Raquel C., Castilho, Antonio L., Costa, Rogério C., Zara, Fernando J. & Mantelatto, Fernando L., 2018, Checklist of decapods (Crustacea) from the coast of the São Paulo state (Brazil) supported by integrative molecular and morphological data: I. Infraorder Caridea: families Hippolytidae, Lysmatidae, Ogyrididae, Processidae and Thoridae in Zootaxa 4370 (1)</i>, DOI: 10.11646/zootaxa.4370.1.6, <a href="http://zenodo.org/record/1138546">http://zenodo.org/record/1138546</a>
The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing
No full textLin-41 is a stem cell-specific E3 ligase and a known target of the tumour suppressor microRNA (miRNA) let-7. Lin-41 was recently reported to mediate ubiquitylation and degradation of the miRNA pathway protein Ago2. We demonstrate that Lin-41 is over-expressed in hepatocellular carcinoma (HCC). Lin-41 over-expression correlates with high a-fetoprotein level, high tumour grade and high tumour stage and predicts early tumour recurrence. Lin-41 is a strong predictor of poor long-term survival for patients with HCC. Lin-41 knock-down by RNA interference in HCC cell lines Huh7 and Hep3B suppressed proliferation in vitro and reduced in vivo tumour growth in NOD/SCID mice. On the other hand, over-expression of Lin-41 in the HCC cell line SK-Hep1 enhanced tumourigenicity. Over-expression and knock-down of Lin-41 led to inverse changes in the levels of Ago1 and Ago2 proteins. Over-expression of Ago1 and Ago2 reduced in vivo tumour growth. Lin-41 over-expression suppressed let-7 activity in HCC cell lines and expression of Lin-41 enhanced the expression of let-7-regulated oncogenes c-Myc, Lin-28B, HMGA2 and type 1 insulin-like growth factor receptor (IGF1R). Expression of Lin-28B and c-Myc enhanced the expression of Lin-41. Chromatin immunoprecipitation and reporter assays revealed direct association of c-Myc with the Lin-41 promoter, resulting in transcriptional transactivation. Our results indicate that Lin-41 plays an important role in the growth of HCC by regulating RISC complex proteins Ago1 and Ago2 to inhibit miRNA-mediated gene silencing and promote the expression of oncogenic proteins. Lin-41 is also a strong prognostic factor for patients with HCC. Copyright (C) 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd
Lysmata ankeri Rhyne & Lin 2006
No full textLysmata ankeri Rhyne & Lin, 2006 Lysmata ankeri Rhyne & Lin, 2006: 179, figs. 7–9, pl. 1C. Material examined. Brazil, São Paulo: 4 ind (3 ov), CCDB 3829, Ubatuba, off shore (35 m), coll. D. Rosa, 5– 14.ix.2011; 1 ind, CCDB 3831, Ubatuba, off shore (25–40 m), coll. D. Rosa, 15–17.viii.2011; 1 ind (1 ov), CCDB 3830, Ubatuba, off shore (30–40 m), coll. D. Rosa, 15–28.xi.2011; 1 ind, CCDB 4715, Ubatuba, Ilha das Couves, coll. D. Alves, 13.vi.2013; 1 ind, CCDB 1606, Santos, coll. A. Castilho et al., 24.x.2011. Distribution. Western Atlantic—USA (Florida), Haiti, Venezuela, Panama, Suriname, French Guyana, Brazil (Bahia to São Paulo) (Rhyne & Lin 2006; Alves et al. 2015; Barros-Alves et al. 2016). Previous records. Ubatuba, Couves Island (Alves et al. 2015; Barros-Alves et al. 2016). Remarks. DNA sequences matched with the sequences of L. ankeri used in the previous studies (Fiedler et al. 2010; Figure 3), confirming our morphological identification (see discussion section for more details). Sequences accession number (GenBank): CCDB 4715 - 16S (KU312981), COI (KU313010).Published as part of Terossi, Mariana, Almeida, Alexandre O., Buranelli, Raquel C., Castilho, Antonio L., Costa, Rogério C., Zara, Fernando J. & Mantelatto, Fernando L., 2018, Checklist of decapods (Crustacea) from the coast of the São Paulo state (Brazil) supported by integrative molecular and morphological data: I. Infraorder Caridea: families Hippolytidae, Lysmatidae, Ogyrididae, Processidae and Thoridae in Zootaxa 4370 (1), DOI: 10.11646/zootaxa.4370.1.6, http://zenodo.org/record/113854
On the sheaf-theoretic SL(2, C) Casson–Lin invariant
No full textWe prove that the (τ-weighted, sheaf-theoretic) SL(2, C) Casson–Lin invariant introduced by Manolescu and the first author is generically independent of the parameter τ and additive under connected sums of knots in integral homology 3-spheres. This addresses two questions asked by Manolescu and the first author. Our arguments involve a mix of topology and algebraic geometry, and rely crucially on the fact that the SL(2, C) Casson–Lin invariant admits an alternative interpretation via the theory of Behrend functions.</p
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