967 research outputs found
‐Koordination ermöglicht durch die Wasserstoffbildungsreaktion (HER)
No full textFundacja na rzecz Nauki Polskiej https://doi.org/10.13039/501100001870European Research Council https://doi.org/10.13039/501100000781Narodowa Agencja Wymiany Akademickiej https://doi.org/10.13039/501100014434China Scholarship Council https://doi.org/10.13039/50110000454
sj-xlsx-1-tct-10.1177_15330338231202881 - Supplemental material for Bronchoalveolar Lavage as Potential Diagnostic Specimens to Genetic Testing in Advanced Nonsmall Cell Lung Cancer
No full textSupplemental material, sj-xlsx-1-tct-10.1177_15330338231202881 for Bronchoalveolar Lavage as Potential Diagnostic Specimens to Genetic Testing in Advanced Nonsmall Cell Lung Cancer by Xuwen Lin, Yazhou Cai, Chenyu Zong, Binbin Chen, Di Shao, Hao Cui, Zheng Li and Ping Xu in Technology in Cancer Research & Treatment</p
Distraction osteogenesis at the proximal third of the ulna for the treatment of Masada type I/IIb deformities in children with hereditary multiple exostoses: a retrospective review of twenty cases
No full textBackgroundUlna distraction by monolateral external fixator (MEFix) is a good option for the treatment of Masada type I and IIb deformities in children with hereditary multiple exostoses (HMEs). However, there is no consensus regarding where to perform ulnar osteotomy. Our hypothesis is that osteotomy at the proximal third of the ulna and progressive distraction with MEFix can simultaneously correct elbow and wrist deformities in patients with HME.MethodsWe retrospectively reviewed patients with HME who underwent ulna distraction osteogenesis from June 2014 to March 2019. The carrying angle (CA), radial articular angle (RAA), ulnar variance (UV), radial variance (RV) and range of motion (ROM) of the affected forearm and elbow were clinically assessed before lengthening and at the last follow-up visit. The total ulna lengthening distance (LD) and radiographic outcome were also recorded.ResultsNineteen patients (20 forearms) with HME aged 9.1 ± 2.4 years at the time of surgery were retrospectively reviewed. The mean follow-up period was 26.1 ± 5.6 months. There were 11 patients (12 forearms) with Masada type I deformities and eight patients (8 forearms) with Masada type IIb deformities. Patients with type IIb deformity had higher RV, lower CA values, less elbow flexion and forearm pronosupination than those with type I deformity (p < 0.05); RV was an independent risk factor for radial head dislocation, with the cut off at RV > 15.5 mm. The mean LDs in patients with type I and type IIb deformities were 33.6 ± 6.6 mm and 41.4 ± 5.4 mm, respectively. The mean CA, UV, RV, forearm pronation and ulna deviation at the wrist improved significantly following surgery in all patients. In particular, five of eight patients (62.5%) with type IIb deformities had concentric reduction of the radiocapitellar joint, while no radial head subluxation was detected in patients with type I deformities at the last follow-up. Three complications were recorded: two pin-track infections and one delayed union.ConclusionsDistraction osteogenesis at the proximal third of the ulna provides satisfactory clinical and radiological outcomes in patients with Masada type I and IIb deformities. Early treatment of Masada type I deformities is indicated before progression to more complex type IIb deformities.Background: Ulna distraction by monolateral external fixator (MEFix) is a good option for the treatment of Masada type I and IIb deformities in children with hereditary multiple exostoses (HMEs). However, there is no consensus regarding where to perform ulnar osteotomy. Our hypothesis is that osteotomy at the proximal third of the ulna and progressive distraction with MEFix can simultaneously correct elbow and wrist deformities in patients with HME. Methods: We retrospectively reviewed patients with HME who underwent ulna distraction osteogenesis from June 2014 to March 2019. The carrying angle (CA), radial articular angle (RAA), ulnar variance (UV), radial variance (RV) and range of motion (ROM) of the affected forearm and elbow were clinically assessed before lengthening and at the last follow-up visit. The total ulna lengthening distance (LD) and radiographic outcome were also recorded. Results: Nineteen patients (20 forearms) with HME aged 9.1 ± 2.4 years at the time of surgery were retrospectively reviewed. The mean follow-up period was 26.1 ± 5.6 months. There were 11 patients (12 forearms) with Masada type I deformities and eight patients (8 forearms) with Masada type IIb deformities. Patients with type IIb deformity had higher RV, lower CA values, less elbow flexion and forearm pronosupination than those with type I deformity (p < 0.05); RV was an independent risk factor for radial head dislocation, with the cut off at RV > 15.5 mm. The mean LDs in patients with type I and type IIb deformities were 33.6 ± 6.6 mm and 41.4 ± 5.4 mm, respectively. The mean CA, UV, RV, forearm pronation and ulna deviation at the wrist improved significantly following surgery in all patients. In particular, five of eight patients (62.5%) with type IIb deformities had concentric reduction of the radiocapitellar joint, while no radial head subluxation was detected in patients with type I deformities at the last follow-up. Three complications were recorded: two pin-track infections and one delayed union. Conclusions: Distraction osteogenesis at the proximal third of the ulna provides satisfactory clinical and radiological outcomes in patients with Masada type I and IIb deformities. Early treatment of Masada type I deformities is indicated before progression to more complex type IIb deformities
Response to Jacques Caton, MD’s comments on the article “Distraction osteogenesis at the proximal third of the ulna for the treatment of Masada type I/IIb deformities in children with hereditary multiple exostoses: a retrospective review of twenty cases” by Lu et al
No full textsj-pdf-1-imr-10.1177_03000605221094644 - Supplemental material for Associations between bone mineral density and chronic obstructive pulmonary disease
No full textSupplemental material, sj-pdf-1-imr-10.1177_03000605221094644 for Associations between bone mineral density and chronic obstructive pulmonary disease by Xiaodiao Zhang, Keke Ding, Xiaqi Miao, Jianing Wang, Binbin Hu, Jiamin Shen, Xueting Hu, Yage Xu, Beibei Yu, Tingting Tu, Aiju Lin, Xianjing Chen and Yiben Huang in Journal of International Medical Research</p
Electroreductive room-temperature C–H activations with RuCl 3 · n H 2 O precatalyst via cathodic ruthenium( iii / ii ) manifold
No full textElectroreductive C–H activations with RuCl 3 · n H 2 O precatalyst proceed at exceedingly mild temperatures. Detailed mechanistic studies offer evidence for a cathodic ruthenium( iii / ii ) manifold, along with the involvement of a biscyclometalated species.We, herein, disclose a strategy to directly utilize user-friendly RuCl 3 · n H 2 O for ortho - as well as meta -C–H functionalizations at low temperatures. The key to success was the in situ formation of the active ruthenium catalyst through cathodic electron transfer, setting the stage for C–H activations under exceedingly mild reaction conditions. The robustness of our electrocatalysis process was highlighted by the late-stage diversification of compounds of relevance to chemical, agrochemical, and pharmaceutical industries, as well as simple amines as terminal reductants for the electroreduction. Detailed mechanistic studies by, among others, spectroelectrochemical analysis provided strong evidence for a cathodic reduction manifold.Electroreductive C–H activations with RuCl 3 · n H 2 O precatalyst proceed at exceedingly mild temperatures. Detailed mechanistic studies offer evidence for a cathodic ruthenium( iii / ii ) manifold, along with the involvement of a biscyclometalated species.We, herein, disclose a strategy to directly utilize user-friendly RuCl 3 · n H 2 O for ortho - as well as meta -C–H functionalizations at low temperatures. The key to success was the in situ formation of the active ruthenium catalyst through cathodic electron transfer, setting the stage for C–H activations under exceedingly mild reaction conditions. The robustness of our electrocatalysis process was highlighted by the late-stage diversification of compounds of relevance to chemical, agrochemical, and pharmaceutical industries, as well as simple amines as terminal reductants for the electroreduction. Detailed mechanistic studies by, among others, spectroelectrochemical analysis provided strong evidence for a cathodic reduction manifold.Deutsches Zentrum für Herz-Kreislaufforschung https://doi.org/10.13039/100010447China Scholarship Council https://doi.org/10.13039/501100004543European Research Council https://doi.org/10.13039/501100000781Fonds der Chemischen Industrie https://doi.org/10.13039/100018992Deutsche Forschungsgemeinschaft https://doi.org/10.13039/501100001659Horizon 2020 Framework Programme https://doi.org/10.13039/10001066
Direct imaging of self-assembly behaviors of colloids: from the microscale plates to the nanoscale cubes
No full textMicroscale and nanoscale colloidal particle self-assembly is widely studied to establish the design rules towards ordered structures and used as atomic model systems for phase transition studies such as crystallization and growth. The well-established synthetic library enables the synthesis of colloidal particles with controllable size, morphology, and surface chemistry, which dictates their interactions for self-assembly. This dissertation focuses on studying a promising yet underexplored colloidal building blocks: anisometric colloids and developing direct imaging tool of liquid-phase transmission electron microscopy (TEM) to visualize and quantify the less-explored nanoparticle self-assembly dynamics in solution. I begin by engineering highly directional interactions of micron-sized silver plates through colloidal synthesis and surface functionalization, to induce their co-assembly with patchy spheres into complex, 2D architectures. Utilizing a combination of direct optical microscopy imaging, theoretical modeling, and automated single particle tracking, I further demonstrate an unconventional crystallization pathway into 3D hierarchical lattices from polydisperse colloids. Then I focus on a foundationally new imaging tool known as liquid-phase TEM for in-situ imaging of otherwise inaccessible solution-phase nanoparticle self-assembly dynamics at nanometer resolution. I substantially advanced this technique and revealed, for the first time, the nanoparticle assembly dynamics such as a layer-by-layer growth process into flat superlattices. This dissertation concludes by highlighting new opportunities from this technical improvement in navigating colloidal interactions to engineer the conformation, phase behaviors and collective dynamics of colloids on the nanometer length scale. The generalized interaction engineering strategy from my research can serve as a general guideline for the design and fabrication of functional colloidal materials from the bottom-up.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-05-01The student, Binbin Luo, accepted the attached license on 2020-04-27 at 11:12.The student, Binbin Luo, submitted this Dissertation for approval on 2020-04-27 at 11:34.This Dissertation was approved for publication on 2020-05-04 at 09:49.DSpace SAF Submission Ingestion Package generated from Vireo submission #15080 on 2020-08-25 at 17:41:00Made available in DSpace on 2020-08-27T00:50:03Z (GMT). No. of bitstreams: 5
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Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemOpen Restriction set for Item 115892 on 2021-04-19T17:48:55Z with date null by [email protected] Restriction set for Item 115892 on 2021-04-19T17:49:00Z with date null by [email protected] of I Only Restriction set for Item 115892 on 2021-08-03T16:07:04Z with date 2023-08-03 by [email protected] of I Only Restriction set for Item 115892 on 2021-08-03T16:07:08Z with date 2023-08-03 by [email protected] of the author which was approved by thesis office.U of I Onl
Polypropylene base lithium ion battery separator membrane with excellentproperty prepared by melt-blown method
No full textNovel polypropylene based separators for lithium ion battery(LIB)was successfully prepared viamelt-blown method.Compared with commercial polypropylene based separators,melt-blown separator exhibited both higher mechanical strength and improved absorption rate and wet ability for electrolyte,relating to its inter-connected inside continuous micro-fibrous structures.Due to its excellent properties,thecapacity and cycling stability of LIBs assembled with novel melt-blown separator were greatly improved athigher charging or discharging rates.The thermal property measurement for the separator made by meltblown method also showed superior thermal barrier property,which may enhance the safety of lithium ionbattery
Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification
No full textElectrooxidation has emerged as an increasingly viable platform in molecular syntheses that can avoid stoichiometric chemical redox agents. Despite major progress in electrochemical C−H activations, these arene functionalizations generally require directing groups to enable the C−H activation. The installation and removal of these directing groups call for additional synthesis steps, which jeopardizes the inherent efficacy of the electrochemical C−H activation approach, leading to undesired waste with reduced step and atom economy. In sharp contrast, herein we present palladium-electrochemical C−H olefinations of simple arenes devoid of exogenous directing groups. The robust electrocatalysis protocol proved amenable to a wide range of both electron-rich and electron-deficient arenes under exceedingly mild reaction conditions, avoiding chemical oxidants. This study points to an interesting approach of two electrochemical transformations for the success of outstanding levels of position-selectivities in direct olefinations of electron-rich anisoles. A physical organic parameter-based machine learning model was developed to predict position-selectivity in electrochemical C−H olefinations. Furthermore, late-stage functionalizations set the stage for the direct C−H olefinations of structurally complex pharmaceutically relevant compounds, thereby avoiding protection and directing group manipulations.Open-Access-Publikationsfonds 202
Effects of culturally tailored hypertension education program among Chinese Americans
No full textPurpose of Project: Hypertension (HTN) prevalence in Asians has risen dramatically compared with other ethnic groups in recent years. This quality improvement project used a faith-based setting to provide an HTN education program to improve awareness and management of HTN among Chinese. This project aimed to assess the effectiveness of the HTN education program on HTN knowledge, self-monitoring blood pressure (SMBP) techniques, lifestyle modification behaviors, and blood pressure (BP) measurement.
Methodology: This project used a pre-and post-test design with interventions using American Heart Association (AHA) guided HTN education. Ten participants were recruited at a local Chinese Church. The participants received 60 minutes of in-person educational sessions on weeks one and two while providing baseline HTN knowledge, lifestyle modification behavior, SMBP, and BP measurement. The participants also received weekly text message reminders on weeks three and four regarding lifestyle modification. On Week Five, the participants repeated the HTN knowledge test, survey behavior changes, SMBP, and completed the program evaluation survey. Descriptive statistics, McNemar's test, and the Wilconxon-signed rank test were used to analyze the data.
Results: Although there was no statistical significance of the overall change. When comparing participants' individual results, there were noted differences. There was an improvement in HTN knowledge, SMBP, lifestyle modification and BP measurement.
Implication for Practice: The project results consigned with previous research with the need to focus on HTN education in primary care settings. Integrating HTN knowledge, lifestyle modification, and proper SMBP can help manage HTN. Reinforcement of lifestyle modification can work synergistically along with pharmacological therapy. A simple health program can fill gaps in the primary care setting by improving patient quality and safety. Thus, reducing the morbidity of HTN complications and reducing the economic burden. This project demonstrated a faith-based community as an excellent opportunity for implementing a population culturally tailored health program.D.N.P.Includes bibliographical reference
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