218 research outputs found
La nefrite secondaria alla porpora di Schoenlein-Henoch e la nefropatia a depositi IgA: una o due malattie?
No full textLa nefropatia a depositi IgA (IgAN) è la glomerulonefrite più comune nei giovani. La nefrite
secondaria a porpora di Schoenlein-Henoch, attualmente definita vasculite da IgA (IgAVN)
è una malattia rara molto conosciuta fin dal secolo scorso fra i pediatri. I depositi glomeru-
lari di IgA prevalenti sulle altre immunoglobuline sono caratteristica comune a entrambe.
Negli anni sono stati chiariti molti elementi patogenetici comuni.
Le due malattie presentano una grande variabilità clinica di esordio, risposta terapeutica
ed evoluzione ed è ipotizzabile che il ruolo del background genetico sia fondamentale
nell’influenzare la risposta infiammatoria a stimoli comuni.
Sia nella IgAN primitiva che nella IgAVN è caratteristico il riscontro di IgA con difetto di
galattosilazione, che le rende auto-antigeniche, inducendo la formazione di autoanticorpi
e immunocomplessi, che si depositano nel mesangio glomerulare oppure nei capillari si-
stemici.
Alla biopsia renale le lesioni istologiche sono indistinguibili fra IgAN e IgAVN e attualmente
classificate secondo un modo standardizzato e validato.
La IgAVN del bambino è frequentemente lieve e autolimitantesi rispetto alla IgAN, con
meccanismi immunologici ancora in gran parte ignoti. Entrambe possono avere decorso
molto severo, richiedendo follow-up fino all’età adulta per il rischio di perdita della funzione
renale a lungo termine in una percentuale non trascurabile di casi
La strada maestra del Master
No full textIl volume raccoglie una serie di contributi sui temi e sui problemi dell’alta formazione nel settore nel campo della comunicazione, da parte di studiosi, docenti, professionisti, collaboratori e allievi, italiani e stranieri, del Master in Comunicazione e Media della Facoltà di Scienze Politiche “Cesare Alfieri” dell’Università degli Studi di Firenze. L’intervento di Gaia Peruzzi riflette sulle modalità formative e sul valore del suddetto master a partire dall’esperienza che l’autrice vi ha fatto, nella duplice veste prima di allieva, poi di collaboratrice alla progettazione e all’organizzazione didattica.The essay is a report on the educational value of the Masters in Communication and Media at the Faculty of Political Science "Cesare Alfieri" of the University of Florence, starting from the experience of the author, in the double role first as student, then as a collaborator to the planning and didactic organisation
Case Report: Role of Ketone Monitoring in Diabetic Ketoacidosis With Acute Kidney Injury: Better Safe Than Sorry
No full textBACKGROUND: Type 1 Diabetes (T1D) is a well-known endocrinological disease in children and adolescents that is characterized by immune-mediated destruction of pancreatic β-cells, leading to partial or total insulin deficiency, with an onset that can be subtle (polydipsia, polyuria, weight loss) or abrupt (Diabetic Keto-Acidosis, hereafter DKA, or, although rarely, Hyperosmolar Hyperglycemic State, hereafter HHS). Severe DKA risk at the onset of T1D has recently significantly increased during the SARS-CoV-2 pandemic with life-threatening complications often due to its management. DKA is marked by low pH (7.3) and bicarbonates (>15 mmol/L) with no or very low ketone bodies. Despite this, ketone monitoring is not universally available, and DKA diagnosis is mainly based on pH and bicarbonates. A proper diagnosis of the right form with main elements (pH, bicarbonates, ketones) is essential to begin the right treatment and to identify organ damage (such as acute kidney injury). CASE PRESENTATIONS: In this series, we describe 3 case reports in which the onset of T1D was abrupt with severe acidosis (pH < 7.1) in the absence of both DKA and HHS. In a further evaluation, all 3 patients showed acute kidney injury, which caused low bicarbonates and severe acidosis without increasing ketone bodies. CONCLUSION: Even if it is not routinely recommended, a proper treatment that included bicarbonates was then started, with a good response in terms of clinical and laboratory values. With this case series, we would like to encourage emergency physicians to monitor ketones, which are diriment for a proper diagnosis and treatment of DKA
La prova del licenziamento ritorsivo nella legge 179/17 sul whistleblowing
No full textThe essay examines the legislative protection of the whistleblower introduced by Act n. 179/17, focusing on a specific aspect, namely the rule on the burden of proof. As Act no. 179 establishes a reversed burden of proof in favour of the employee, the analysis compares this rules with those otherwise applicable in the case of retaliatory, discriminatory and unfair dismissals. After highlighting differences, systemic issues, and possible risks, the author proposes some interpretative solutions
(Il nuovo) Anno Zero delle questioni di genere. Le sfide per la comunicazione sociale
No full textNel panorama mutevole delle relazioni di genere contemporanee, l'autrice individua le nuove priorità sociali, rispetto alle tematiche dei femminismi classici, e illustra le sfide che ne derivano per la comunicazione sociale.In the uncertain landscape of gender question, the author identifies the new social priorities,in respect of traditional feminist movements, and illustrates the challanges for social communication
Effectiveness and Problematic Aspects of the EU Framework on Psychosocial Risks
No full textThe aim of this chapter is to reconstruct the regulatory framework concerning the prevention of psychosocial risks (PSRs) in the context of the European Union law and to assess its effectiveness.The analysis retraces the references to this topic, from the first Health-and-Safety at Work action programme of 1978 to the Communication on the Modernisation of the EU Occupational Safety and Health Legislation and Policy published by the Commission in 2017 . Specifically, it highlights how these references found their roots and were translated into EU law, both through hard law sources, as interpreted by the Court of Justice, and soft law regulatory instruments, issued by the EU institutions or the social partners at European level. In this reconstruction, the author points out how the key question underlying the development of the EU regulatory system in the field of PSRs does not concern the actual existence of a solid protection basis at hard law level – which can be properly identified within the 89/391/EEC directive as interpreted by the ECJ and the European Commission – but rather to the effectiveness of such protection and to the functionality of soft law in ensuring its implementation and detailing its content
Viaggio nella “terra di mezzo”, tra contratti leader e pirata
No full textMoving from a reconstruction of the position of Confsal, as an “autonomousμ trade union, in the current system of industrial relations, and from a comparison between the collective agreements signed by Cifa- Confsal and those of Cgil, Cisl, and Uil, the essay investigates on the use of the concepts of “leaderμ and “pirateμ agreements. This permits to address, on a more general level, issues connected to the measurement and comparison of unions’ representativeness as well as to the definition of sectors. In this perspective, the author wonders on the possibility to shift from a mere comparison between subjects to a comparison of contents; as well as from a comparison (of subjects and contents) based on quantitative data to a comparison that includes qualitative aspects
Presenze mediali. Le immigrate straniere sui quotidiani sardi
No full textIl volume “Straniere in Sardegna” racconta i risultati di alcune ricerche sulle esperienze e sulle rappresentazioni delle donne immigrate residenti sull’isola. In particolare, il capitolo in questione è dedicato alle rappresentazioni sulle medesime diffuse dai mass media locali. Quale ruolo svolgono i quotidiani locali nell’interazione fra autoctoni e nuovi abitanti di un territorio? Quali immagini essi diffondono della popolazione immigrata femminile presso i lettori sardi e più in generale sul territorio? Le risposte si basano sui risultati di una ricerca, effettuata nel 2006, durante la quale sono stati raccolti, classificati e analizzati tutti gli articoli pubblicati l’anno precedente dai due maggiori quotidiani dell’isola, aventi per protagonisti donne e uomini immigrati. Dopo aver ricostruito il quadro delle presenze straniere proposto dai giornali del territorio, l’autrice si sofferma a ricostruire in maniera più dettagliata i profili femminili.The book "Straniere in Sardegna" records the results of some researches on the experiences and representations of migrant women residing on the island. In particular, the present article is dedicated to their representation in local mass media channels. What is the role of local daily newspapers in the interaction between natives and new residents inside a territory? What kind of images do they spread about the female migrant population to the Sardinians readers, and more generally out in the territory? The answers are based on results of a research conducted in 2006, when all the articles on male and female migrants issued by the two major local newspapers during the previous years had been gathered, classified and analysed.
After reconstructing the general picture on foreigners presence on the territory as suggested by the newspapers, the author lingers on creating more detailed female profiles
Grown up Youngstairs. New Profiles of Immigrants Girls in Italy
No full textWho are and how do the young daughters of immigration live in Italy today? What are the reference values and the expectations for the future of the girls coming from a foreign family that grow up within the Italians? What attracts them and what do they reject of their lifestyles and of Westerner cultures? What are the major obstacles they meet, within their family and outside, in their path into social integration? What strategies of identity do they enact in order to live with the daily dilemma filled of callings from such different cultures?
This paper narrates the final results of the research project Media, mode e amori dei figli dell’immigrazione [Media, fashions and loves of the children of immigration], an investigation that aimed mainly at the questions mentioned above, and that identified in the analysis of cultural costumes, of the expressive styles and of the sentimental relations of the territory, still unknown to Italian literature, useful to penetrate the private sphere of these existences. On the basis of the stories of the 45 young migrants interviewed, all between 17 and 25 years of age, resident in Rome and in the adjacent provinces, the author proposes the recourse to a new social category – that of the adult youths – as an ideal type to synthesizes certain reoccurring traits in the biographies of the young immigrant women in Italy
Coppie miste di oggi. La mixité sentimentale nell'Italia del nuovo millennio
No full textLe coppie miste sono uno degli indicatori più importanti dell’integrazione fra autoctoni e immigrati su un territorio. Il fenomeno sta cominciando a crescere e a rendersi visibile anche in Italia. Questo articolo, basandosi sui risultati di alcune ricerche condotte fra il 2003 e il 2008 in diverse province italiane, ricostruisce nei tratti più significativi il profilo e la vita delle unioni sentimentali composte da italiani e nuovi immigrati: la nascita della relazione, il percorso che conduce alla convivenza e al matrimonio, le reazioni di familiari e conoscenti, le differenze che creano opportunità e conflitti tra i partner.Cross-cultural couples are one of the most important indicator of integration between natives and immigrants living within the same territory. This is an emergent phenomenon today in Italy. Using the data of some researches conducted by the author from 2003 to 2008, this article sketches out the profiles and the family life of cross-cultural couples formed by an Italian wife/husband and an immigrant partner: the first encounter, the beginnings of the relationship, the decision to live together and to marry, the family’s and friends’ reactions, the differences that create problems and/or opportunities in the private life
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