1,723,292 research outputs found
Taiwan’s Chinese Medicine Giant:Chen Li-Fu
No full textTraditionally, the topic of physicians locates at the center of the history of medicine. This article, however, takes Li-Fu Chen (1900-2001), a mining engineer trained in the U.S., and his achievements as examples to underscore that Chen's systemic infrastructures of the industry-government-university on traditional Chinese medicine (TCM) profoundly contributed to the development of TCM in Taiwan after the Second World War. By analyzing the oublished documents and interview records, this article argues that the role of Li-Fu Chen played in the development of TCM in Taiwan was not only a proponent, having continued the advocacies of "saving Nation through science" and "scientizing Chinese medicine" in China since the early 20th century; Chen's role was also an engineer, constructing infrastructures for developing TCM in Taiwan.This article first introduces Li-Fu Chen's dedication to the National Government, the Institute of National Medicine, and the education of saving China in the period of the Republic of China (1912-1949). The second part indicates that Chen zealously intertwined TCM, science, and Confucianism during Taiwan's Chinese Cultural Renaissance Movement (1966-1991). Finally, this article focuses on Chen's all-out efforts to develop TCM infrastructures in Taiwan, including TCM's higher education, medical institutions, academic research, and textbook publications
Taiwan’s Chinese Medicine Giant:Chen Li-Fu
No full textTraditionally, the topic of physicians locates at the center of the history of medicine. This article, however, takes Li-Fu Chen (1900-2001), a mining engineer trained in the U.S., and his achievements as examples to underscore that Chen's systemic infrastructures of the industry-government-university on traditional Chinese medicine (TCM) profoundly contributed to the development of TCM in Taiwan after the Second World War. By analyzing the oublished documents and interview records, this article argues that the role of Li-Fu Chen played in the development of TCM in Taiwan was not only a proponent, having continued the advocacies of "saving Nation through science" and "scientizing Chinese medicine" in China since the early 20th century; Chen's role was also an engineer, constructing infrastructures for developing TCM in Taiwan.This article first introduces Li-Fu Chen's dedication to the National Government, the Institute of National Medicine, and the education of saving China in the period of the Republic of China (1912-1949). The second part indicates that Chen zealously intertwined TCM, science, and Confucianism during Taiwan's Chinese Cultural Renaissance Movement (1966-1991). Finally, this article focuses on Chen's all-out efforts to develop TCM infrastructures in Taiwan, including TCM's higher education, medical institutions, academic research, and textbook publications
Attenuated the Cardiac Mitochondrial-dependent Apoptotic effects by Li-Fu Formula in hamsters fed with a hypercholesterol diet
No full text[[abstract]]Apoptosis involves in the pathogenesis of various cardiac abnormalities. This study intends to evaluate the effects of Li-Fu formula on cardiac apoptosis induced by hyper-cholesterol diet. Twenty-four male Golden Syrian hamsters were randomly divided into Control, Cholesterol and Li-Fu formula groups. Histopathological analysis, western blotting and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assays were performed to measure the effects of Li-Fu formula on left ventricle. Significantly reduced TUNEL-positive cells and mitochondria- dependent apoptosis were observed in the left ventricle of hamsters from Li-Fu formula group compared to the Cholesterol group. Additionally, induced cardiac insulin like growth factor I receptor (IGFIR)-dependent survival pathway was detected in the Li-Fu formula group compared to the Cholesterol group. Besides, minor fibrosis, increased collagen deposition, and myofibril disarray was detected in the Cholesterol group, whereas the reductions of collagen deposition and myofibril disarray were observed in the Li-Fu formula group. This study demonstrated that Li-Fu formula not only reduced the mitochondria-dependent apoptosis and fibrosis, but also enhanced the IGF-I survival pathway in the left ventricle from high cholesterol-fed hamsters. We suggest the protective effects of Li-Fu formula on cardiac apoptosis and therapeutic potentials against cardiovascular disease
VICTRE-example-data
No full text VICTRE-phantom-example. An example of raw data generated from VICTRE software tool. This raw VICTRE data can be used to generate acoustic phantoms by employing our tissue properties assignment code {breast_id}.raw.gz: A compressed 3D anatomical data with a resolution of 0.05 mm. {breast_id}.mhd: A header file for this phantom that contains the physical location of the voxel with index [0, 0, 0]. The total number of voxels in the x, y, and z, and the voxel size. ; (2021-03-31
Ameliorate Effects of Li-Fu Formula on IL-6-mediated Cardiac Hypertrophy in Hamsters Fed with a Hyper-cholesterol Diet
No full text[[abstract]]Hypercholesterolemia diets are considered as major sources to cause cardiac hypertrophy. This study intends to evaluate the effects of Li-Fu formula on cardiac hypertrophy induced by hypercholesterolemia diet. Twenty-four male Golden Syrian hamsters were randomly divided into control, cholesterol and Li-Fu formula groups and fed with different experimental diets for 2 months. Histopathological analysis and western blotting were performed to measure the myocardial architecture, and various cardiac hypertrophy-associated molecules in the excised left ventricle from hamsters. The ratios of whole heart weight/body weight (BW) and left ventricle weight/BW were significantly higher in the cholesterol group but significantly lower in the Li-Fu formula group. The protein levels of both atrial natriuretic peptide and brain natriuretic peptide were significantly increased in the cholesterol group but significantly reduced in the Li-Fu formula group. Additionally, significantly increased interleukin-6, STAT3, MEK5, p-ERK5 and non-cardiomyocyte proliferate signal molecules such as p-MEK and p-ERK, were detected in the cholesterol group but significantly reduced in the Li-Fu formula group. Notably, no significant variations of inflammatory signaling molecules, including p-P38 and p-JNK, were detected in all groups. Our experimental results demonstrated the significant reductions of cardiac hypertrophy and related eccentric hypertrophy signaling, non-cardiomyocyte proliferate signaling in the excised left ventricle of hamsters from the Li-Fu formula. We suggested the protective effects of Li-Fu formula on cardiac hypertrophy that may be useful in prevention or treatment of hypertrophy-associated cardiovascular diseases
Ameliorate Effects of Li-Fu Formula on IL-6-Mediated Cardiac Hypertrophy in Hamsters Fed with a Hyper-Cholesterol Diet
Full text linkHypercholesterolemia diets are considered as major sources to cause cardiac hypertrophy. This study intends to evaluate the effects of Li-Fu formula on cardiac hypertrophy induced by hypercholesterolemia diet. Twenty-four male Golden Syrian hamsters were randomly divided into control, cholesterol and Li-Fu formula groups and fed with different experimental diets for 2 months. Histopathological analysis and western blotting were performed to measure the myocardial architecture, and various cardiac hypertrophy-associated molecules in the excised left ventricle from hamsters. The ratios of whole heart weight/body weight (BW) and left ventricle weight/BW were significantly higher in the cholesterol group but significantly lower in the Li-Fu formula group. The protein levels of both atrial natriuretic peptide and brain natriuretic peptide were significantly increased in the cholesterol group but significantly reduced in the Li-Fu formula group. Additionally, significantly increased interleukin-6, STAT3, MEK5, p-ERK5 and non-cardiomyocyte proliferate signal molecules such as p-MEK and p-ERK, were detected in the cholesterol group but significantly reduced in the Li-Fu formula group. Notably, no significant variations of inflammatory signaling molecules, including p-P38 and p-JNK, were detected in all groups. Our experimental results demonstrated the significant reductions of cardiac hypertrophy and related eccentric hypertrophy signaling, non-cardiomyocyte proliferate signaling in the excised left ventricle of hamsters from the Li-Fu formula. We suggested the protective effects of Li-Fu formula on cardiac hypertrophy that may be useful in prevention or treatment of hypertrophy-associated cardiovascular diseases.</jats:p
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