3,024 research outputs found

    Cut-elimination, substitution and normalisation

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    Date of Acceptance: 01/2015We present a proof (of the main parts of which there is a formal version, checked with the Isabelle proof assistant) that, for a G3-style calculus covering all of intuitionistic zero-order logic, with an associated term calculus, and with a particular strongly normalising and confluent system of cut-reduction rules, every reduction step has, as its natural deduction translation, a sequence of zero or more reduction steps (detour reductions, permutation reductions or simplifications). This complements and (we believe) clarifies earlier work by (e.g.) Zucker and Pottinger on a question raised in 1971 by Kreisel.Peer reviewe

    WinD (James P.) Lewis (James W.) eds. American Congregations Vol 1. Portraits of Twelve Religious Congregations ; Vol 2. New Perspectives the Study of Congregations

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    Richet Isabelle. WinD (James P.) Lewis (James W.) eds. American Congregations Vol 1. Portraits of Twelve Religious Congregations ; Vol 2. New Perspectives the Study of Congregations. In: Archives de sciences sociales des religions, n°100, 1997. pp. 139-140

    I remember teaching English at Seabrook

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    In this "I remember" memoir, Isabell Waugh, a former teacher at Seabrook, compares and constrasts the different groups of students she taught. She remembers that native-born American teenagers tended to be more concerned with athletics and social activities, than academic matters. In comparison, Estonian and Japanese parents did not tolerate low academic performance, so students from the two groups often competed intensely with each other for academic achievement and recognition. Isabelle recalls that the Estonians were, in general, more sophisticated and better educated. Most of the children knew 3-5 languages, and were more advanced in math and science. She sensed that some Estonian parents felt that their homes at Seabrook were temporary, and that they would be returning to Estonia at some point. The Seabrook Educational and Cultural Center has been soliciting current and past residents of Seabrook Farms for an "I remember" project. Residents are asked to create narratives regarding their experiences at Seabrook Farms. These memories help preserve the history and multi-cultural heritage of Seabrook Farms

    Lewis Christian Jensen

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    Lewis Christian Jensen is the husband of Isabelle Mecham. He was born April 3, 1873 and died December 15, 1943

    Space, time and the artist : the philosophy and aesthetics of Wyndham Lewis.

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    My study, in Part I of this thesis, of Wyndham Lewis's philosophical principles outlined in Time and Western Man (1927), reveals a mode of thought which is inspired and determined by beliefs about visual art and its metaphysical significance. The ultimate rejection of the philosophies of Bergson, Schopenhauer and Nietzsche and the 'Space-Timeists' such as Spengler, Whitehead and Alexander, in pursuit of a 'philosophy of the eye' was, I argue, fashioned according to aesthetic objections. 'Time-values' are challenged by 'space-values', ideally expressible for Lewis in the static, spatial medium of visual art. The aesthetics of Vorticism, discussed in Part II, was formalized in the two Blast journals (1914-15), and provides the key to an understanding of Lewis's later philosophy in its negation of Bergsonist-related doctrines. His aversion to chronologism' had emerged in various ways well before the public launch of Vorticism and had subsequently achieved a subtle, effective coherence in the 'logic of contradictions' which directed the theoretical strategies of Blast. But In modernism Lewis recognized 'empty' abstraction and thus the taint of the time-cult itself. As a method of working, abstraction was not abandoned, but was directed away from the sensational and emotional in the service of intellect and rational thought. In order to clarify the interdependence of art and philosophy in Lewis's thought, I propose two schematic models. The first characterizes Lewis's philosophical principles and posits the concept of the vortex as Lewis's noumenon. The second superimposes the aesthetic values and form of the vortex symbol itself as a prior justification of the philosophical schema: each 'model' is clearly incomplete without cognizance of the other. Since, for Lewis, the essential character of Vorticism was first expressed in art practice, the findings of this thesis support Lewis's own retrospective view (1956), that Vorticism was a 'new philosophy' in visual form

    Synthesis of Tetrasaccharide and Pentasaccharide Fragments of the Tumor-Associated Carbohydrate Antigen Lewis A Lewis X

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    Lewis A Lewis X is a Tumor Associated Carbohydrate Antigen specifically expressed on the surface of squamous lung carcinoma cells. Because Carbohydrates are involved in immune response, this characteristic makes it a potential target for carbohydrate-based vaccine design. This thesis describes the synthesis of the tetra- and penta-saccharide fragments of the Lewis A Lewis X. Tetrasaccharide 1 was synthesized in an overall yield of 8% from N-acetylglucosamine acceptor 9. Both pentsaccharide framents 2 and 3 were synthesized from tetrasacharide acceptor 12 in two and three steps respectivily. These fragments will be tested for cross reactivity using competitive enzyme linked immunosorbent assay (ELISA). Positive results from the competive binding studies will pave the way for glyconjugate vaccine design against Lewis A Lewis X Tumor Associated Carbohydrate Antigen.Natural Sciences and Engineering Research Council of Canad

    Isabelle Bell to Susan Niemcewicz, December 23, 1800

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    Isabelle Bell wrote to Susan U. Niemcewicz in Elizabethtown, New Jersey. Bell expressed her disappointment in not receiving a line from Susan. She sent Bell Lucretia Rephans subscription epistle, but Susan refrained from writing a letter to her. Bell did not execute any of Susan’s commissions in New York because her time there was short. Miss Resham heard that Mr. B Livingston told his sister, Mrs. J. Livingston that he would offer Bell a salary to live in his house and take charge of his children’s education. Asked if Susan what she thought of her being an author and if Susan would subscribe to a small volume that may have the good fortune to rival the poems of the immortal Scarron.https://digitalcommons.kean.edu/lhc_1800s/1143/thumbnail.jp

    Interviews with Carl T. Bode, Isabelle Fritschen, Joseph H. Hirt, Mary G. Hirt, and Minnie Campbell

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    Interviews with Carl T. Bode, Isabelle Fritschen, Joseph H. Hirt, Mary G. Hirt, and Minnie Campbell. The recording includes a variety of German-language songs. The last half of the recording is dedicated to Minnie Campbell telling about her time working for Mother Bickerdyke. The first few minutes of the recording are missing. 00:00:13 - Song, The Messenger Bird sung by Joseph H. Hirt and translated by Isabelle Fritschen 00:01:35 - Song, Birdie in the Window, sung by Mary Gertrude Hirt 00:02:59 - Story of Peter John Thielen\u27s experience in the Franco-Prussian War told by Joseph Hirt 00:05:27 - Grandfather\u27s experience with wild cattle told by Isabelle Fritschen 00:07:31 - Carl T. Bode introduction 00:08:46 - Nursery rhyme about hands 00:09:09 - The Cuckoo and the Donkey 00:09:42 - Sleep Baby Sleep 00:10:24 - Golden Evening Sun 00:11:00 - Beautiful Moon 00:12:10 - My Homeland 00:13:50 - Minnie Campbell Introduction 00:14:05 - Experiences as Mother Bickerdyke\u27s secretary 00:14:35 - Mother Bickerdyke\u27s 81st birthday celebration in Bunker Hill, KS 00:19:59 - Mother Bickerdyke\u27s portrait 00:23:55 - How Lydia Foster, Mother Bickerdyke\u27s Black maid came to live with her. 00:26:34 - Mother Bickerdyke\u27s death 00:29:34 - Mother Bickerdyke\u27s burial in Galesburg, Illinois 00:30:28 - Working for Mother Bickerdyke 00:34:01 - Going to School as a student of James Bickerdyke, Mother Bickerdyke\u27s son 00:35:26 - Decline of Bunker Hill, KS 00:37:15 - Russell stealing the county seat from Bunker Hill 00:38:09 - Closing of the Dorrance, KS bank 00:39:00 - Mother Bickerdyke\u27s personality 00:42:34 - Experience with Nina Brown Baker author of Cyclone in Calico 00:48:24 - Mother Bickerdyke Home for Widows and Children in Ellsworth, KS 00:51:13 - Post scripthttps://scholars.fhsu.edu/sackett/1014/thumbnail.jp

    Mapping the Epitopes Recognized by Monoclonal Anti-Lewis X and Anti-Lewis A Antibodies

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    Aberrant glycosylation is a common biochemical phenomenon associated with cancer. The aberrations in glycan structure, referred to as Tumor Associated Carbohydrate Antigens (TACAs), offer a promising avenue for targeted cancer immunotherapy, specifically for the design of epitope-based vaccines. The primary goal of designing such vaccines is to be able to target these antigens while avoiding an autoimmune response. Therefore, the understanding of the immunogenic potential of the specific antigen is critical in the development of TACA-based vaccines. Epitope mapping of monoclonal antibodies (mAbs) is a widely used technique in evaluating the immunogenic potential of such target antigens. Two TACAs of particular interest to our research group are the dimeric Lewis X (dimLex) and Lewis A Lewis X (LeaLex) hexasaccharides. Herein, we describe the characterization of three anti-TACA mAbs: IG5F6, SH2 and SPM 522. The work presented here provides valuable insight into identifying promising TACA-based therapeutic targets
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