2,019 research outputs found
Ibandronate does not increase risk of atrial fibrillation in analysis of pivotal clinical trials.
No full textSummary Objective:?To determine the incidence of adverse events or serious adverse events of atrial fibrillation in the pivotal trials of ibandronate and to assess whether increasing dose or duration of exposure had any effect on the incidence of atrial fibrillation. Patients and methods:?Pooled data from all four pivotal ibandronate clinical trials were analysed to assess the incidence of atrial fibrillation as an adverse event and serious adverse event with ibandronate vs. placebo. The incidence of atrial fibrillation with ibandronate was also assessed by dose, by annual cumulative exposure (ACE) and by patient age. Results:?This analysis included 6830 patients treated with ibandronate and 1924 treated with placebo. The incidence of atrial fibrillation as an adverse event (ibandronate, 0.8% and placebo, 0.9%) and serious adverse event (0.4% for both ibandronate and placebo) was comparable between the ibandronate and placebo groups. There was no increase in the incidence of atrial fibrillation as an adverse event or serious adverse event with increasing oral or intravenous (i.v.) ibandronate dose. No correlation between the incidence of atrial fibrillation as a serious adverse event and ibandronate duration of exposure was observed. Based on various ACE categories, none of the ibandronate regimens evaluated in these trials was associated with an increased incidence of atrial fibrillation. Conclusions:?In this pooled analysis of all four ibandronate pivotal trials, including analysis by ACE, all studied ibandronate regimens, including the licensed doses of 150?mg monthly oral and 3?mg quarterly i.v., were not associated with an increased incidence of atrial fibrillation
E.M. Jellinek: The Hungarian connection
No full textThis is the second in a series of papers depicting the mostly undocumented life of E.M. Jellinek. This paper establishes the connection between Jellinek Morton, a well-known figure in Hungary in the early part of the 20th Century, and E.M. Jellinek, one of the founders of alcohol studies. Newly found documents in Hungary and at the Rutgers Center of Alcohol Studies Library and Archives provide compelling evidence of this connection and shed some light on the mysterious circumstances of his 1920 disappearance from Hungary. The information in these papers was first presented at the 36th Annual Substance Abuse Librarians and Information Specialists (SALIS) Conference on May 1st, 2014, by seven presenters in a panel entitled “Mystery and speculations: Piecing together E.M. Jellinek’s redemption.”Peer reviewe
Special report on the official positions of the International Society for Clinical Densitometry
No full textThe International Society for Clinical Densitometry (ISCD) periodically holds Position Development Conferences (PDCs) for the purpose of establishing standards and guidelines for indications, acquisition, and interpretation of bone density tests. Topics are selected for consideration by the ISCD Scientific Advisory Committee, reviewed by scientific working groups, and presented to an international panel of experts. Topic categories addressed to date include indications for bone density testing, selection of reference databases for T-scores and Z-scores, clinical applications for central and peripheral bone densitometry, serial bone density testing, instrument precision assessment, phantom scanning and calibration testing, requirements for a bone density report, nomenclature, and diagnosis of osteoporosis in postmenopausal women, premenopausal women, men, and children. Following an open session for public comment and discussion, the panel convenes for consideration of each topic and makes recommendations for positions to the ISCD Board of Directors. Recommendations that are accepted become the Official Positions of the ISCD. This Special Report summarizes the methodology of the ISCD PDCs and presents selected Official Positions of general interest.[Anonymous], 2002, COCHRANE REV HDB; Binkley NC, 2002, J CLIN DENSITOM, V5, pS39; Bonnick SL, 2001, J CLIN DENSITOM, V4, P105, DOI 10.1385-JCD:4:2:105; Delmas PD, 2000, OSTEOPOROSIS INT, V11, P189, DOI 10.1007-s001980050280; Hamdy Ronald C, 2002, J Clin Densitom, V5 Suppl, pS11, DOI 10.1385-JCD:5:3S:S11; Kanis JA, 2000, BONE, V27, P585, DOI 10.1016-S8756-3282(00)00381-1; KANIS JA, 1994, OSTEOPOROSIS INT, V4, P368, DOI 10.1007-BF01622200; Kanis JA, 2000, OSTEOPOROSIS INT, V11, P192, DOI 10.1007-s001980050281; Leib E, 2004, J CLIN DENSITOM, V7, P27; Leib E, 2004, J CLIN DENSITOM, V7, P37; Leib E, 2004, J CLIN DENSITOM, V7, P7; Leib E, 2004, J CLIN DENSITOM, V7, P45; Leib ES, 2004, J CLIN DENSITOM, V7, P1, DOI 10.1385-JCD:7:1:1; Leib Edward S, 2002, J Clin Densitom, V5 Suppl, pS5, DOI 10.1385-JCD:5:3S:S05; Lenchik Leon, 2002, J Clin Densitom, V5 Suppl, pS29, DOI 10.1385-JCD:5:3S:S29; Lenchik Leon, 2002, J Clin Densitom, V5 Suppl, pS1, DOI 10.1385-JCD:5:3S:S01; Marshall D, 1996, BRIT MED J, V312, P1254; MELTON LJ, 1995, J BONE MINER RES, V10, P175; Miller Paul D, 2002, J Clin Densitom, V5 Suppl, pS39, DOI 10.1385-JCD:5:3S:S39; National Osteoporosis Foundation, 2003, PHYS GUID PREV TREAT; SANDRICK K, 1998, DIAGN IMAGING SAN S, P8; Leib E, 2004, J CLIN DENSITOM, V7, P17; Berg AO, 2002, ANN INTERN MED, V137, P526; Leib E, 2004, J CLIN DENSITOM, V7, P1344363
Tomb with a view: three recent publications by E.M. Forster
No full text6000-word review article concerning three recent collections of essays, broadcasts and diaries by English modernist novelist, author and critic E.M. Forste
Hayo Haya Maaseh [= Once upon a time]
No full textAnthology of East European Jewish folklore, with introduction and sources. The anthology includes: songs, tales, traditions, customs, jokes, proverbs, riddles. Authored by Chaim Ben Zion Elon-Baranik (born 1901). Published immediately after the Second World War. Illustrations by Moritz Oppenheimer, L. Pilichowski, Yosef Budko, E.M. Lilien (his signature in print). Most of the illustrations are printed on separated chrome paper, on one side of the page. Folklore publishing, Tel Aviv. HaIvri press, Jerusalem. 22 em. [1],303, [3] pages. Excellent condition. Chipped top of spine. . '... Olb price140-160This is a hardbound book (hard cover)Language note: HebrewChaim Ben Zion Elon-Barani
Integrated difference: Counteracting exclusion of migrants through intercultural spatial planning and governance in Athens
No full textThis research-and-design research addresses the influence of urban conditions on social conditions (and vice versa) and explores interdisciplinary alternatives. In the context of Athens (Greece), spatial planning and its governance support social exclusion of migrants, which is expressed through conflicts with native residents. The project experiments with alleviating these effects by establishing spatial planning as active agent of integration. The main aim of the research is to develop an appropriate strategy in areas with migrants, by re-adjusting the principles of urban space. Instead of providing one fixed solution, the project will design flexible initiatives that help the community achieve the desirable outcome. The methodology of this urban integration can be replicable, provided that it is adjusted for similar urban and social contexts
Letter from E.M. Rowalt, Acting Regional Director, War Relocation Authority, to Mr. Joseph Smart, Regional Director, War Relocation Authority, September 29, 1942
No full textCorrespondence from E.M. Rowalt to Joseph Smart regarding the transportation and storage of incarcerees personal belongings.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications
Psycholinguistic Characteristics of the Discourse with a «Colour Black» Component (based on E.M. Remarque’s works)
No full textIn recent decades, colour vocabulary has been actively studied by the Ukrainian and foreign scientists. Modern Linguistics has significant achievements in research of this issue, however, some of its aspects, in particular, psycholinguistic characteristics of the discourse with a colour element, still remain relevant and poorly researched.
Colour has always played an important role in artistic discourse. The names of individual writers are
inextricably associated with certain coloronyms, which is a so-called marker in their work.
One example of this phenomenon is the colour black, that is dominant in the discourse of E.M. Remarque, which, given the mostly dramatic themes of the author’s novels, is quite expected, especially if the
fact is considered through the prism of Psycholinguistics.
The purpose of the given scientific investigation is to provide psycholinguistic characteristics of the
discourse with the «black colour» component in E.M. Remarque’s works and to identify the impact it has
on the reader in the process of perceiving the outstanding author’s texts.
Implementation of the stated tasks of research involved the integrational usage of general scientific methods (such as description, induction, deduction), as well as the analysіs of dictionary definitions, current native and foreign psycholinguistic sources; contextual and structural-thematic analysis; modelling
and classification of actual material.
The results of the analysis of the Remarque’s discourse with the «black colour» component allow us
drawing the following conclusion: the coloronym «schwarz» in E.M. Remarque’s is characterised by a wide
semantic content, wherein the black colour is used by the writer both to determine the colour of the described object neutrally and to convey figurative negative semantics.
Lexemes denoting black, in their direct meaning, indicate the colour of the depicted object directly.
Using the colour nomination «schwarz» in symbolic meaning, the author resorts to «painting» in dark natural phenomena, which are not characterised by black; depicts dishonest and illegal actions; demonstrates
negative attitude towards people.
Using the specified colour nomination as the colour of clothing, objects, buildings, as well as emotions,
experiences and feelings, non-verbal means of intensification the semantics of “black” – the designation of
poses, gestures, facial expressions, body movements the author demonstrates not only his personal attitude
towards the characters of his novels, but by focusing the consciousness of the reader on their difficult psychological and physical state, he encourages to rethink the causes and consequences of their actions.
Stable association with the black colour, peculiar for a long historical and cultural development of
mankind, and therefore with sad events in human life, losses, failures, loneliness, is verbalized in all analysed Remarque’s works. Thus, the black colour is the necessary element of the psycholinguistic portrait of
Remarque’s character
A Polyphonic Study of E.M. Forsters A Passage to India and George Orwell’s Burmese Days
No full textThe purpose of this study is to examine the multi-voicedness techniques in E.M. Forster’s A Passage to India and George Orwell’s Burmese Days, in terms of the narrator’s role and the plurality of voices and consciousnesses. This paper used the concept of polyphony which was coined by Bakhtin as a methodology in analyzing and examining the aforesaid novels. The results of this study showed that; First, both novels used the omniscient narrator as a narrative technique, since the voice of the author was evident on more than one occasion. Moreover, there was an influence by the omniscient narrator on the reader, which might be considered significant on more than one occasion, in controlling and manipulating his decisions and views in A Passage to India, while the influence was minuscule in Burmese Days. Second, this paper proved that the aforesaid novels are polyphonic ones. Finally, both authors gave a considerable margin of freedom for each character to express their ideologies freely
The analysis of social values in E.M. Forster’s a passage to India
No full textABSTRACT
Literary, works give many useful values and messages. It also gives contribution to build up sensitivity to the environment. By literature, the author has to be sensitive to the social condition in his or her society. Moreover, literature is a reflection of life experience that includes various aspects of both personal and social lives. One form of literary works is novel, which is usually tells about the condition of one society. Social values have many influences in the society. It can also determine whether one’s action to other people is proper or not and suitable with the social values or not. By value, we can determine whether something is good or bad. So, from statement above, social values can be considered as a truth and it is become the standard for people to act in order to achieve democratic and harmonious life.
A Passage to India contains social values that are revealed through the major and minor characters and their society. Related to this case, the problems of the study can be formulated: (1) What social values are found in E.M. Forster’s A Passage to India and (2) What are the implications of the social values to the theme of E.M. Forster’s A Passage to India. Thus, the purposes of the study are to find out the social values found in E M. Forster’s A Passage to India and to explain the implications of the social values to the theme of E.M. Forster’s A Pusxuge to India.
This research is classified into literary criticism because she tries to find out the social phenomena concerning the social values described in a literary work. In order to reach the goal, she uses structural approach. Structural approach is an approach that is used to analyze a literary work by interpreting and focusing on the text alone, apart from the author and reader. With structural approach, the researcher analyzes about social values and the implications of social values to the theme which are found in the novel.
In E.M. Forster’s م Passage to India, social values are described by describing the condition of one society. Those social values are revealed through the presentation of the major and minor character’s behavior especially Dr. Aziz and Mrs. Moore who make social relationship with their society and family. The social values that the researcher found in A Passage {() India are humanity, social relationship, family relationship and moral. In social relationship are divided into four kinds, they are; cooperation, competition, conflict and accommodation. After analyze the social values, generally we can know that the implication of the social values to the theme of the novel is power, and all of the major activities of the novel revolve around power and social class. Because the novel is tells about the occupation of India by the British, so that the researcher wants to analyze about social values that exist in that society. Power have make the British become arrogant and disrespectful to India, they also discriminate the social class. That wilt cause cooperation, competition, conflict and accommodation between the British and Indian
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