1,354,361 research outputs found
Black, Green and Silver Striped Lerose Dress
No full textLong dress with scooped square neck; long sleeves. A line shape with two vertical darts down the front and darted at bust. Long zip to centre back. Green and metalic horizontal stripes on a green background, which become wider at the hem. Label: Lerose, 16, Made in Britain. Maker: Lerose - from the The Betty Smithers Design Collection at Staffordshire University.
Gastric cancer following bariatric surgery: a review.
No full textBACKGROUND:: Bariatric procedures can induce a massive weight loss that lasts for >15 years after surgery; in addition, they achieve important metabolic effects including diabetes resolution in the majority of morbidly obese patients. However, some bariatric interventions may cause gastroesophageal reflux disease and other serious complications. The aim of our study is to evaluate the risk of cancer after bariatric surgery. METHODS:: We conducted a review of the literature about the cases of gastric cancer arising after any bariatric procedure, including a case of adenocarcinoma incidentally discovered by the authors 6 months after laparoscopic adjustable gastric banding. RESULTS:: Globally, 17 case reports describing 18 patients were retrieved, including the case study by the authors. The diagnosis of tumor was at a mean of 8.6 years after bariatric surgery, 9.3 years after RYGB, and 8.1 years after restrictive procedures. The adenocarcinoma represented most cases (15 patients, 83%). In the patients with RYGB, the adenocarcinoma was localized in the excluded stomach in 5 patients (83%) and in the pouch in 1 patient (17%). After a restrictive procedure, the cancer was localized in the pouch in 5 patients (62.5%), in the pylorus in 2 patients (25%), and in lesser curvature only in 1 patient (12.5%). CONCLUSIONS:: There is a lack of evidence about a connection between the late occurrence of gastric adenocarcinoma and the bariatric surgery. For this reason, although the preoperative upper endoscopy is still mandatory, there is no need for a regular endoscopic evaluation of patients after surgery. © 2014 by Lippincott Williams & Wilkins.BACKGROUND:
Bariatric procedures can induce a massive weight loss that lasts for >15 years after surgery; in addition, they achieve important metabolic effects including diabetes resolution in the majority of morbidly obese patients. However, some bariatric interventions may cause gastroesophageal reflux disease and other serious complications. The aim of our study is to evaluate the risk of cancer after bariatric surgery.
METHODS:
We conducted a review of the literature about the cases of gastric cancer arising after any bariatric procedure, including a case of adenocarcinoma incidentally discovered by the authors 6 months after laparoscopic adjustable gastric banding.
RESULTS:
Globally, 17 case reports describing 18 patients were retrieved, including the case study by the authors. The diagnosis of tumor was at a mean of 8.6 years after bariatric surgery, 9.3 years after RYGB, and 8.1 years after restrictive procedures. The adenocarcinoma represented most cases (15 patients, 83%). In the patients with RYGB, the adenocarcinoma was localized in the excluded stomach in 5 patients (83%) and in the pouch in 1 patient (17%). After a restrictive procedure, the cancer was localized in the pouch in 5 patients (62.5%), in the pylorus in 2 patients (25%), and in lesser curvature only in 1 patient (12.5%).
CONCLUSIONS:
There is a lack of evidence about a connection between the late occurrence of gastric adenocarcinoma and the bariatric surgery. For this reason, although the preoperative upper endoscopy is still mandatory, there is no need for a regular endoscopic evaluation of patients after surgery
Classical microscopic theory of polaritons in ionic crystals
No full textIt is well known that the optical branches of the dispersion curves of ionic crystals exhibit a polaritonic feature, i.e., a splitting about the electromagnetic dispersion line ω = ck. This phenomenon is consid-ered to be due to the retardation of the electromagnetic forces among the ions. However, the problem is usually discussed at a phenomeno-logical level, through the introduction of a macroscopic polarization field, so that a microscopic treatment is apparently lacking. A micro-scopic first principles deduction is given here, in a classical frame, for a model in which the ions are dealt with as point charges. At a quali-tative level it is made apparent that retardation is indeed responsible for the splitting. A quantitative comparison with the empirical data for LiF is also given, showing a fairly good agreement over the whole Brillouin zone
Nonequilibrium phenomena in quantum many-body systems with long-range interactions
No full textThe focus of this thesis work is on the role of long-range interactions in the nonequilibrium coherent quantum dynamics. I have explored a number of settings in which long-range interactions allow for phenomena which do not possess a counterpart in equilibrium. The results contained in this thesis contribute to establish long-range interactions as a source of anomalous nonthermal behavior in quantum many-particle systems. In particular, the two parts of the thesis discuss two relative underlying mechanisms, which involve long-range interactions in different ways
Dynamical scaling of correlations generated by short- and long-range dissipation
No full textWe study the spatio-temporal spreading of correlations in an ensemble of
spins due to dissipation characterized by short- and long-range spatial
profiles. We consider systems initially in an uncorrelated state, and find that
correlations widen and contract in a novel pattern intimately related to both
the dissipative nature of the dynamical channel and its spatial profile.
Additionally, we make a methodological contribution by generalizing
non-equilibrium spin-wave theory to the case of dissipative systems and derive
equations of motion for any translationally invariant spin chain whose dynamics
can be described by a combination of Hamiltonian interactions and dissipative
Lindblad channels. Our work aims at extending the study of correlation dynamics
to purely dissipative quantum simulators and compare them with the established
paradigm of correlations spreading in hamiltonian systems.Comment: 10 pages, 2 figures, builds on topic introduced in arXiv:2101.06445v
Lipegfilgrastim in the management of chemotherapy-induced neutropenia of cancer patients
No full textRoberto Guariglia,1 Maria Carmen Martorelli,1 Rosa Lerose,2 Donatella Telesca,2 Maria Rita Milella,2 Pellegrino Musto3 1Unit of Hematology and Stem Cell Transplantation, 2Pharmacy Service, 3Scientific Direction, IRCCS, Referral Cancer Center of Basilicata, Rionero in Vulture, Potenza, Italy Abstract: Neutropenia and febrile neutropenia (FN) are frequent and potentially fatal toxicities of myelosuppressive anticancer treatments. The introduction of granulocyte colony-stimulating factors (G-CSFs) in clinical practice has remarkably reduced the duration and severity of neutropenia, as well as the incidence of FN, thus allowing the administration of chemotherapeutic agents at the optimal dose and time with lower risk. The current scenario of G-CSFs in Europe includes filgrastim, lenograstim, some G-CSF biosimilars, and pegfilgrastim. Recently, a novel long-acting G-CSF, lipegfilgrastim, became available. Lipegfilgrastim is a glycopegylated G-CSF, alternative to pegfilgrastim, and has shown in randomized trials, to be equivalent to pegfilgrastim in reducing the incidence of severe neutropenia and FN in patients with breast cancer receiving chemotherapy, with a similar safety profile. Furthermore, lipegfilgrastim was more effective than the placebo in reducing the incidence of severe neutropenia, its duration, and time to absolute neutrophil count recovery, in patients with non-small cell lung cancer receiving myelosuppressive therapy. Although the number of studies currently published is still limited, lipegfilgrastim seems to be a promising drug in the management of chemotherapy-induced neutropenia. Keywords: neutropenia, febrile neutropenia, granulocyte colony-stimulating factors, G-CSF, pegfilgrastim, lipegfilgrasti
Chaotic dynamical ferromagnetic phase induced by nonequilibrium quantum fluctuations
No full textWe investigate the robustness of a dynamical phase transition against quantum fluctuations by studying the impact of a ferromagnetic nearest-neighbor spin interaction in one spatial dimension on the nonequilibrium dynamical phase diagram of the fully connected quantum Ising model. In particular, we focus on the transient dynamics after a quantum quench and study the prethermal state via a combination of analytic time-dependent spin wave theory and numerical methods based on matrix product states. We find that, upon increasing the strength of the quantum fluctuations, the dynamical critical point fans out into a chaotic dynamical phase within which the asymptotic ordering is characterized by strong sensitivity to the parameters and initial conditions. We argue that such a phenomenon is general, as it arises from the impact of quantum fluctuations on the mean-field out of equilibrium dynamics of any system which exhibits a broken discrete symmetry
Correlation engineering via nonlocal dissipation
No full textControlling the spread of correlations in quantum many-body systems is a key challenge at the heart of quantum science and technology. Correlations are usually destroyed by dissipation arising from coupling between a system and its environment. Here, we show that dissipation can instead be used to engineer a wide variety of spatiotemporal correlation profiles in an easily tunable manner. We describe how dissipation with any translationally invariant spatial profile can be realized in cold atoms trapped in an optical cavity. A uniform external field and the choice of spatial profile can be used to design when and how dissipation creates or destroys correlations. We demonstrate this control by generating entanglement preferentially sensitive to a desired spatial component of a magnetic field. We thus establish nonlocal dissipation as a route toward engineering the far-from-equilibrium dynamics of quantum information, with potential applications in quantum metrology, state preparation, and transport
Off-label use of anti-cancer drugs between clinical practice and research: the Italian experience
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