1,316 research outputs found
The author as actor: a defense of Quentin Skinner
No full textIn this thesis, I defend Quentin Skinner's work against some criticisms raised by three of his interlocutors: John Keane, Kennet Minogue, and Joseph Femia. All three of these critics take issue with Skinner's author-centered approach to the historical interpretation of texts. Femia, invoking Roland Barthes 'death of the author' thesis, argues that Skinner's attempt to recover the intentions of authors is impossible. While Minogue and Keane do not dispute the possibility of recovering an author's intentions, they question the unity of such an enterprise. In order to answer Femia's criticism of Skinner, I draw an analogy between Skinner's figure of the author, and Arendt's figure of the political actor. I argue that just as it is possible for someone to know what a political actor is doing in performing a political act, it is similarly possible for an intellectual historian to understand what political acts an author was doing in writing his or her text. To refute Minogue's and Keane's claims that a Skinnerian approach to intellectual history is of no use to the political theorist, I point to three examples of how Skinner's recovery of forgotten political discourses have been applied to contemporary debates in political theory.Graduat
Drawing Sacred Forests and Courtyards in South Benin
No full texthttps://drawingmatter.org/drawing-sacred-forests-and-courtyards-in-south-benin/The following conversation between the editors of Accattone and Quentin Nicolaï was first published in Accattone 6 (2019). It documents research carried out by Quentin Nicolaï in Abomey, Benin, between January 2014 and June 2018.Drawing Matter would like to thank the author and the magazine’s editors for allowing us reproduce the essay on www.drawingmatter.org.info:eu-repo/semantics/nonPublishe
Features of auteur cinema in Quentin Tarantino's works
No full textMultimediju komunikācijaInformācijas un komunikācijas zinātnesMultimedia CommunicationInformation and Communication SciencesBakalaura darba tēmas nosaukums ir “Autorkino iezīmes Kventina Tarantīno daiļradē.”
Pētījumā izvirzītā hipotēze apgalvo, ka režisora Kventina Tarantīno (Quentin Tarantino) filmās ir
atrodamas autorkino iezīmes.
Bakalaura darba mērķis ir noskaidrot autorkino iezīmes Kventina Tarantīno sešās
ietekmīgākajās un skatītāju atzītākajās filmās, kuras tika atlasītas pēc Internacionālās filmu datu
bāzes. Darbā tiek apskatītas un analizētas sešas no Kventina Tarantīno filmām, kuras ir “Trakie
suņi” (Reservoir Dogs), “Lubene” (Pulp Fiction), “Nogalināt Bilu: 1. daļa” (Kill Bill: Vol. 1) un
“Nogalināt Bilu: 2. daļa” (Kill Bill: Vol. 2), kas pēc paša režisora uzskatiem ir, viena vesela, filma
sadalīta divās daļās, kā arī filmas “Bēdīgi slavenie mērgļi” (Inglorious Bastards), “Atsvabinātais
Džango” (Django Unchained) un “Reiz Holivdā” (Once Upon a Time... in Hollywood).
Darba mērķa izpildei teorētiskajā daļā tika aplūkots autorkino jēdziens, Holivudas
klasiskais kino stils, kino valoda, kā arī Kventina Tarantīno biogrāfija, lai palīdzētu izprast un
analizēt atlasītās filmas. Par pētījuma metodi tika izvēlēta kvalitatīvā kontentanalīze.The title of the bachelor's thesis is "Features of auteur cinema in Quentin Tarantino's
works" The study’s hypothesis states that directors Quentin's Tarantino's films have the features
of an author.
The purpose of the bachelor's thesis is to find out the influence of author cinema on Quentin
Tarantino's six most influential and audience-recognized films selected from the International Film
Database. Work is discussed and analyzed in six of Quentin Tarantino films, which are “Reservoir
Dogs”, “Pulp Fiction”, “Kill Bill: Vol. 1” and “Kill Bill: Vol. 2”, which the director says is a whole
movie divided into two parts, as well as “Inglorious Bastards”, “Django Unchained” and “Once
Upon a Time ... in Hollywood”.
The theoretical part of the paper explored the concept of author cinema, Hollywood classic
cinema, film language, and the biography of Quentin Tarantino to help understand and analyze
selected films. Qualitative content analysis was chosen as the research method
Saint-Quentin et sa région
No full textThe author insists on the seriousness of the trade depression in Saint-Quentin last years (ten per cent workmen out of work, unemployed period above eleven months.). Metallurgy is the principal industry and «Motobécane» the first firm, making the famous «Mobylette» since 1951. Therefore, the difficulties of «Motobécane», of the engineering industry, have effects on the social situation. The town is, from now on, the starting point of an urban emigration. Old fortress on the right bank, protecting the crossing of the river Somme, Saint-Quentin has been destroyed during the first World War and rebuilt without large transformation. The town keeps an heptagonal shape with cross-roads on the both sides of the valley, canal and railway. The attraction area is, to-day, smaller than the Vermandois, very industrialized and populated region. For the future, Saint-Quentin shall have to expect : the «A-26 » motorway, the négociation of an employment agreement («Contrat de Bassin d'Emploi») and, later, the construction of the large-gauge canal «Seine-Nord» from Compiègne to Valenciennes.L'auteur insiste sur la gravité de la crise de remploi à Saint-Quentin aujourd 'hui (taux de chômage supérieur à 1 0%, durée moyenne de chômage supérieure à 11 mois). L'industrie est dominée par la métallurgie et celle-ci par la firme «MOTOBECANE» qui fabrique depuis 1951 les fameuses «mobylettes». Aussi les difficultés de Motobécane ou de l'industrie de la manutention rejaillissent-elles immédiatement sur la situation sociale. La ville est désormais le point de départ d'un véritable exode urbain. Ancienne place forte gardant, sur la rive droite , le passage de la Somme, presque complètement détruit en 1918, mais reconstruit largement à l'identique, St-Quentin a hérité d'une double structure heptagonale et en «patte d'oie» de part et d'autre de la coupure majeure de la vallée de la Somme (canal et voie ferrée). Son aire d'attraction s'est réduite par rapport à la région qui l'entoure, le Vermandois, relativement peuplé et industrialisé lui-même. Pour l'avenir, St-Quentin doit compter surtout, sur l'arrivée de l'autoroute A 26 et sur les efforts qui s'inscriront dans un «Contrat de Bassin d'Emploi», et, à long terme sur la liaison fluviale à grand gabarit «Seine-Nord» utilisant le tracé du canal de St-Quentin.Oudart Paul. Saint-Quentin et sa région. In: Hommes et Terres du Nord, 1981/2. Spécial Picardie. pp. 43-56
A Hundred Years of Photo Wallets:Quentin Blake Centre for Illustration's Book of the Month
No full textAn interview with Annebella Pollen, author of More Than a Snapshot: A Visual History of Photo Wallets, which was selected as the May 2023 Book of the Month by the Quentin Blake Centre for Illustration
Quentin Meillassoux: Facticity and Scientific Methods
No full textThis paper examines Quentin Meillassoux’s critique of correlationism, specifically focusing on the Principle of Factuality and the mathematization of hyperchaos as tools to access the "ancestral." While acknowledging Meillassoux’s significance in overcoming Kantian limits, the author argues that his refusal to return to metaphysics stems from political hesitation rather than ontological necessity. The text critiques the concept of the "God to come" as an ideological compromise. Instead, the author advocates for an "experimental metaphysics" grounded in scientific method, positing that science offers rational access to the absolute and effectively resolving the tension between facticity and the thing-in-itself
Quentin Meillassoux: Facticity and Scientific Methods
No full textThis paper examines Quentin Meillassoux’s critique of correlationism, specifically focusing on the Principle of Factuality and the mathematization of hyperchaos as tools to access the "ancestral." While acknowledging Meillassoux’s significance in overcoming Kantian limits, the author argues that his refusal to return to metaphysics stems from political hesitation rather than ontological necessity. The text critiques the concept of the "God to come" as an ideological compromise. Instead, the author advocates for an "experimental metaphysics" grounded in scientific method, positing that science offers rational access to the absolute and effectively resolving the tension between facticity and the thing-in-itself
A Hundred Years of Photo Wallets:Quentin Blake Centre for Illustration's Book of the Month
No full textAn interview with Annebella Pollen, author of More Than a Snapshot: A Visual History of Photo Wallets, which was selected as the May 2023 Book of the Month by the Quentin Blake Centre for Illustration
Role of indoleamine-2,3-dioxygenase in chronic viral infections
No full textL’indoléamine-2,3-dioxygénase (IDO) est une enzyme du catabolisme du tryptophane suspectée de jouer un double rôle lors des infections en contribuant aux défenses innées de l’hôte et en régulant la réponse immunitaire. IDO est exprimée au cours de l’infection par le virus de l’hépatite C (VHC). Cependant, les mécanismes moléculaires conduisant à l’expression de IDO lors de l’hépatite C et l’impact de IDO sur la réplication virale et sur la réponse immunitaire ne sont pas connus. Dans ce travail de thèse, nous avons montré que le VHC stimule l’expression de IDO dans les hépatocytes.L’expression de IDO était transitoire et coïncidait avec l’expression des interférons (IFNs) de types I et III et avec la transcription de gènes stimulés par les IFNs. L’expression de IDO était également augmentée dans les hépatocytes exposés à la présence de lymphocytes T CD4+ activés et producteurs d’IFN-γ. L’expression hépatique de IDO diminuait la réplication virale, ce qui suggère que IDO limite la diffusion du VHC dans le foie au cours de l’hépatite C. Grâce à des expériences de silencing, nous avons montré que IDO contribue à l’effet antiviral de l’IFN-α sur le VHC. L’expression de IDO était régulée par l’activation des facteurs de transcription IRF-1 et STAT-1 dans les hépatocytes infectés par le VHC. En plus de son effet antiviral sur le VHC, l’expression hépatique de IDO inhibait significativement la prolifération des lymphocytes T CD4+ activés, suggérant un rôle immunorégulateur de IDO au cours de l’hépatite C. Nos données suggèrent donc que IDO joue un double jeu lors de l’hépatite C, en limitant la réplication virale et en régulant la réponse immunitaire adaptative de l’hôte. Notre travail ouvre la voie à des expérimentations in vivo et à des études cliniques visant à préciser la place des inhibiteurs pharmacologiques de IDO dans l’arsenal thérapeutique contre le VHC.Indoleamine-2,3-dioxygenase (IDO) is a tryptophan-catabolizing enzyme that plays a dual role during infectious diseases by contributing to the innate defenses against pathogens and by regulating the immune response. IDO is expressed in patients with hepatitis C virus (HCV) infection. However, the molecular mechanism of IDO induction in HCV infection and its role in the antiviral immune response remain unknown. Using primary human hepatocytes, we have shown that HCV infection stimulates IDO expression. IDO gene induction was transient and coincided with the expression of type I and type III interferons (IFNs) and IFN-stimulated genes (ISGs) in HCV-infected hepatocytes. IDO expression was also stimulated when the hepatocytes were incubated with IFN-γ-secreting CD4+ T cells. Expression of IDO prior to HCV infection significantly impaired HCV replication in hepatocytes, suggesting that IDO limits the spread of HCV in the liver. By using siRNA-mediated IDO knockdown experiments, we have shown that IDO contributes to the IFN-α-antiviral effect on HCV replication. IDO expression was regulated by IRF-1 and STAT-1 in HCV-infected hepatocytes. Hepatic IDO expression also had a significant inhibitory effect on CD4+ T cell proliferation, suggesting an immunoregulatory role of IDO during HCV infection. Our data suggest that hepatic IDO plays a dual role during HCV infection by retarding viral replication and also regulating host immune responses. This work paves the way for in vivo experiments and clinical studies aiming to determine the relevance of pharmacological inhibition of IDO during HCV infection
Rôle de l'indoléamine-2,3-dioxygénase dans la persistance des infections virales
No full textIndoleamine-2,3-dioxygenase (IDO) is a tryptophan-catabolizing enzyme that plays a dual role during infectious diseases by contributing to the innate defenses against pathogens and by regulating the immune response. IDO is expressed in patients with hepatitis C virus (HCV) infection. However, the molecular mechanism of IDO induction in HCV infection and its role in the antiviral immune response remain unknown. Using primary human hepatocytes, we have shown that HCV infection stimulates IDO expression. IDO gene induction was transient and coincided with the expression of type I and type III interferons (IFNs) and IFN-stimulated genes (ISGs) in HCV-infected hepatocytes. IDO expression was also stimulated when the hepatocytes were incubated with IFN-γ-secreting CD4+ T cells. Expression of IDO prior to HCV infection significantly impaired HCV replication in hepatocytes, suggesting that IDO limits the spread of HCV in the liver. By using siRNA-mediated IDO knockdown experiments, we have shown that IDO contributes to the IFN-α-antiviral effect on HCV replication. IDO expression was regulated by IRF-1 and STAT-1 in HCV-infected hepatocytes. Hepatic IDO expression also had a significant inhibitory effect on CD4+ T cell proliferation, suggesting an immunoregulatory role of IDO during HCV infection. Our data suggest that hepatic IDO plays a dual role during HCV infection by retarding viral replication and also regulating host immune responses. This work paves the way for in vivo experiments and clinical studies aiming to determine the relevance of pharmacological inhibition of IDO during HCV infection.L’indoléamine-2,3-dioxygénase (IDO) est une enzyme du catabolisme du tryptophane suspectée de jouer un double rôle lors des infections en contribuant aux défenses innées de l’hôte et en régulant la réponse immunitaire. IDO est exprimée au cours de l’infection par le virus de l’hépatite C (VHC). Cependant, les mécanismes moléculaires conduisant à l’expression de IDO lors de l’hépatite C et l’impact de IDO sur la réplication virale et sur la réponse immunitaire ne sont pas connus. Dans ce travail de thèse, nous avons montré que le VHC stimule l’expression de IDO dans les hépatocytes.L’expression de IDO était transitoire et coïncidait avec l’expression des interférons (IFNs) de types I et III et avec la transcription de gènes stimulés par les IFNs. L’expression de IDO était également augmentée dans les hépatocytes exposés à la présence de lymphocytes T CD4+ activés et producteurs d’IFN-γ. L’expression hépatique de IDO diminuait la réplication virale, ce qui suggère que IDO limite la diffusion du VHC dans le foie au cours de l’hépatite C. Grâce à des expériences de silencing, nous avons montré que IDO contribue à l’effet antiviral de l’IFN-α sur le VHC. L’expression de IDO était régulée par l’activation des facteurs de transcription IRF-1 et STAT-1 dans les hépatocytes infectés par le VHC. En plus de son effet antiviral sur le VHC, l’expression hépatique de IDO inhibait significativement la prolifération des lymphocytes T CD4+ activés, suggérant un rôle immunorégulateur de IDO au cours de l’hépatite C. Nos données suggèrent donc que IDO joue un double jeu lors de l’hépatite C, en limitant la réplication virale et en régulant la réponse immunitaire adaptative de l’hôte. Notre travail ouvre la voie à des expérimentations in vivo et à des études cliniques visant à préciser la place des inhibiteurs pharmacologiques de IDO dans l’arsenal thérapeutique contre le VHC
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