6,051 research outputs found
Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome
No full textThe interactive nature of the 8th Annual Meeting of the Androgen Excess and PCOS Society Annual Meeting in Munich, Germany (AEPCOS 2010) and subsequent exchanges between speakers led to emerging concepts in PCOS regarding its genesis, metabolic dysfunction, and clinical treatment of inflammation, metabolic dysfunction, anovulation and hirsutism. Transition of care in congenital adrenal hyperplasia from pediatric to adult providers emerged as a potential model for care transition involving PCOS adolescents.Selma F. Witchel, Sergio E. Recabarren, Frank González, Evanthia Diamanti-Kandarakis, Kai I. Cheang, Antoni J. Duleba, Richard S. Legro, Roy Homburg, Renato Pasquali, Rogerio A. Lobo, Christos C. Zouboulis, Fahrettin Kelestimur, Franca Fruzzetti, Walter Futterweit, Robert J. Norman, David H. Abbot
The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report
No full textObjectiveTo review all available data and recommend a definition for polycystic ovary syndrome (PCOS) based on published peer-reviewed data, whether already in use or not, to guide clinical diagnosis and future research.DesignLiterature review and expert consensus.SettingProfessional society.PatientsNone.Intervention(s)None.Main outcome measure(s)A systematic review of the published peer-reviewed medical literature, by querying MEDLINE databases, to identify studies evaluating the epidemiology or phenotypic aspects of PCOS.Result(s)The Task Force drafted the initial report, following a consensus process via electronic communication, which was then reviewed and critiqued by the Androgen Excess and PCOS (AE-PCOS) Society AE-PCOS Board of Directors. No section was finalized until all members were satisfied with the contents, and minority opinions noted. Statements were not included that were not supported by peer-reviewed evidence.Conclusion(s)Based on the available data, it is the view of the AE-PCOS Society Task Force that PCOS should be defined by the presence of hyperandrogenism (clinical and/or biochemical), ovarian dysfunction (oligo-anovulation and/or polycystic ovaries), and the exclusion of related disorders. However, a minority considered the possibility that there may be forms of PCOS without overt evidence of hyperandrogenism, but recognized that more data are required before validating this supposition. Finally, the Task Force recognized and fully expects that the definition of this syndrome will evolve over time to incorporate new research findings.Ricardo Azziz, Enrico Carmina, Didier Dewailly, Evanthia Diamanti-Kandarakis, Héctor F. Escobar-Morreale, Walter Futterweit, Onno E. Janssen, Richard S. Legro, Robert J. Norman, Ann E. Taylor, and Selma F. Witchel (Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PCOS Society
Criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: An Androgen Excess Society guideline
No full textCopyright © 2006 by The Endocrine SocietyObjective: The Androgen Excess Society (AES) charged a task force to review all available data and recommend an evidence-based definition for polycystic ovary syndrome (PCOS), whether already in use or not, to guide clinical diagnosis and future research. Participants: Participants included expert investigators in the field. Evidence: Based on a systematic review of the published peer-reviewed medical literature, by querying MEDLINE databases, we tried to identify studies evaluating the epidemiology or phenotypic aspects of PCOS. Consensus Process: The task force drafted the initial report, following a consensus process via electronic communication, which was then reviewed and critiqued by the AES Board of Directors. No section was finalized until all members were satisfied with the contents and minority opinions noted. Statements that were not supported by peer-reviewed evidence were not included. Conclusions: Based on the available data, it is the view of the AES Task Force on the Phenotype of PCOS that there should be acceptance of the original 1990 National Institutes of Health criteria with some modifications, taking into consideration the concerns expressed in the proceedings of the 2003 Rotterdam conference. A principal conclusion was that PCOS should be first considered a disorder of androgen excess or hyperandrogenism, although a minority considered the possibility that there may be forms of PCOS without overt evidence of hyperandrogenism but recognized that more data are required before validating this supposition. Finally, the task force recognized, and fully expects, that the definition of this syndrome will evolve over time to incorporate new research findings.Ricardo Azziz, Enrico Carmina, Didier Dewailly, Evanthia Diamanti-Kandarakis, Hector F. Escobar-Morreale, Walter Futterweit, Onno E. Janssen, Richard S. Legro, Robert J. Norman, Ann E. Taylor and Selma F. Witche
astromatt42/digb_sfgs: Release for 10.21203/rs.3.rs-106679/v1
No full textThis release was used to compute the results in https://doi.org/10.21203/rs.3.rs-106679/v1
For any queries please contact the corresponding author
Harbin Consensus Conference Workshop Group; Conference Chairs: Improving the Reporting of Clinical Trials of Infertility Treatments (IMPRINT): modifying the CONSORT statement
No full textClinical trials testing infertility treatments often do not report on the major outcomes of interest to patients and clinicians and the public (such as live birth) nor on the harms, including maternal risks during pregnancy and fetal anomalies. This is complicated by the multiple participants in infertility trials which may include a woman (mother), a man (father), and result in a third individual if successful, their offspring (child), who is also the desired outcome of treatment. The primary outcome of interest and many adverse events occur after cessation of infertility treatment and during pregnancy and the puerperium, which create a unique burden of follow-up for clinical trial investigators and participants. In 2013, because of the inconsistencies in trial reporting and the unique aspects of infertility trials not adequately addressed by existing Consolidated Standards of Reporting Trials (CONSORT) statements, we convened a consensus conference in Harbin, China, with the aim of planning modifications to the CONSORT checklist to improve the quality of reporting of clinical trials testing infertility treatment. The consensus group recommended that the preferred primary outcome of all infertility trials is live birth (defined as any delivery of a live infant ?20 weeks gestations) or cumulative live birth, defined as the live birth per women over a defined time period (or number of treatment cycles). In addition, harms to all participants should be systematically collected and reported, including during the intervention, any resulting pregnancy, and during the neonatal period. Routine information should be collected and reported on both male and female participants in the trial. We propose to track the change in quality that these guidelines may produce in published trials testing infertility treatments. Our ultimate goal is to increase the transparency of benefits and risks of infertility treatments to provide better medical care to affected individuals and couples. ? The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: [email protected]
Consensus on women's health aspects of polycystic ovary syndrome (PCOS)
No full textPolycystic ovary syndrome (PCOS) is the most common endocrine disorder in females with a high prevalence. The etiology of this heterogeneous condition remains obscure and its phenotype expression varies. Two, widely cited, previous ESHRE/ASRM-sponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008). The present third PCOS consensus paper summarizes current knowledge and identifies knowledge gaps regarding various women’s health aspects of PCOS. Relevant topics addressed—all dealt with in a systematic fashion—include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, ethnicity, pregnancy complications, long-term metabolic and cardiovascular health and finally cancer risk. Additional, comprehensive background information is provided separately in an extended online publication.B.C.J.M. Fauser, B.C. Tarlatzis, R.W. Rebar, R.S. Legro, A.H. Balen, R. Lobo, H. Carmina, R.J. Chang, B.O. Yildiz, J.S.E. Laven, J. Boivin, F. Petraglia, C.N. Wijeyeratne, R.J. Norman, A. Dunaif, S. Franks, R.A. Wild, D. Dumesic and K. Barnhar
#nowplaying-rs
No full text<p>The nowplaying-rs dataset features context- and content features of listening events. It contains 11.6 million music listening events of 139K users and 346K tracks collected from Twitter. The dataset comes with a rich set of item content features and user context features, as well as timestamps of the listening events. Moreover, some of the user context features imply the cultural origin of the users, and some others - like hashtags - give clues to the emotional state of a user underlying a listening event.</p>
<p>The dataset contains three files:</p>
<ul>
<li>user_track_hashtag_timestamp.csv contains basic information about each listening event. For each listening event, we provide an id, the user_id, track_id, hashtag, created_at </li>
<li>context_content_features.csv: contains all context and content features. For each listening event, we provide the id of the event, user_id, track_id, artist_id, content features regarding the track mentioned in the event (instrumentalness, liveness, speechiness, danceability, valence, loudness, tempo, acousticness, energy, mode, key) and context features regarding the listening event (coordinates (as geoJSON), place (as geoJSON), geo (as geoJSON), tweet_language, created_at, user_lang, time_zone, entities contained in the tweet).</li>
<li>sentiment_values.csv contains sentiment information for hashtags. It contains the hashtag itself and the sentiment values gathered via four different sentiment dictionaries: AFINN, Opinion Lexicon, Sentistrength Lexicon and vader. For each of these dictionaries we list the minimum, maximum, sum and average of all sentiments of the tokens of the hashtag (if available, else we list empty values). However, as most hashtags only consist of a single token, these values are equal in most cases. Please note that the lexica are rather diverse and therefore, are able to resolve very different terms against a score. Hence, the resulting csv is rather sparse. The file contains the following comma-separated values: <hashtag, vader_min, vader_max, vader_sum,vader_avg, afinn_min, afinn_max, afinn_sum, afinn_avg, ol_min, ol_max, ol_sum, ol_avg, ss_min, ss_max, ss_sum, ss_avg >, where we abbreviate all scores gathered over the Opinion Lexicon with the prefix 'ol'. Similarly, 'ss' stands for SentiStrength. </li>
</ul>
<p>Please note that user_track_hashtag_timestamp.csv and context_content_features.csv partly provide the same features. We deliberately chose to do so to be able to provide useable files that do not have to be matched and joined with each other to perform e.g., simple recommendation tasks.</p>
<p>Please also find the training and test-splits for the dataset in this repo. Also, Asmita provides prototypical implementations of a context-aware recommender system based on the dataset at https://github.com/asmitapoddar/nowplaying-RS-Music-Reco-FM.</p>
<p><br>
If you make use of this dataset, please cite the following paper where we describe and experiment with the dataset:</p>
<p>@inproceedings{smc18,<br>
title = {#nowplaying-RS: A New Benchmark Dataset for Building Context-Aware Music Recommender Systems},<br>
author = {Asmita Poddar and Eva Zangerle and Yi-Hsuan Yang},<br>
url = {http://mac.citi.sinica.edu.tw/~yang/pub/poddar18smc.pdf},<br>
year = {2018},<br>
date = {2018-07-04},<br>
booktitle = {Proceedings of the 15th Sound & Music Computing Conference},<br>
address = {Limassol, Cyprus},<br>
note = {code at https://github.com/asmitapoddar/nowplaying-RS-Music-Reco-FM},<br>
tppubtype = {inproceedings}<br>
}</p>
Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-sponsored 3rd PCOS Consensus Workshop Group
No full textPolycystic ovary syndrome (PCOS) is the most common endocrine disorder in females, with a high prevalence. The etiology of this heterogeneous condition remains obscure, and its phenotype expression varies. Two widely cited previous ESHRE/ASRM sponsored PCOS consensus workshops focused on diagnosis (published in 2004) and infertility management (published in 2008), respectively. The present third PCOS consensus report summarizes current knowledge and identifies knowledge gaps regarding various women's health aspects of PCOS. Relevant topics addressed-all dealt with in a systematic fashion-include adolescence, hirsutism and acne, contraception, menstrual cycle abnormalities, quality of life, ethnicity, pregnancy complications, long-term metabolic and cardiovascular health, and finally cancer risk. Additional, comprehensive background information is provided separately in an extended online publication.Bart C. J. M. Fauser, Basil C. Tarlatzis, Robert W. Rebar, Richard S. Legro, Adam H. Balen, Roger Lobo, Enrico Carmina, Jeffrey Chang, Bulent O. Yildiz, Joop S. E. Laven, Jacky Boivin, Felice Petraglia, C. N. Wijeyeratne, Robert J. Norman, Andrea Dunaif, Stephen Franks, Robert A. Wild, Daniel Dumesic and Kurt Barnhar
Converter USB/RS 485
No full textThis thesis is describing problematic of realisation of converter from USB type media into the universal RS-485 bus which is mainly used for the industrial applications (author is using frequently as a device in order to enable communication between server and RFID devices). This thesis contains theoretical information, realisation of the device itself and assesment of reached targets
Converter USB/RS 485
No full textThis thesis is describing problematic of realisation of converter from USB type media into the universal RS-485 bus which is mainly used for the industrial applications (author is using frequently as a device in order to enable communication between server and RFID devices). This thesis contains theoretical information, realisation of the device itself and assesment of reached targets
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