34 research outputs found
The Association Between Ambient Air Pollution and Allergic Rhinitis Inception and Control
Correction to: The Association Between Ambient Air Pollution and Allergic Rhinitis Inception and Control
Alergia alimentaria
Food induced adverse reactions include all clinical symptoms attributed to the ingestion of a food
substance or an associated additive and they may be classified, on the basis of the physiopathology
mechanism, into food allergy and food intolerance. Nowadays, food allergy is more frequently diagnosed
but its prevalence does not seem to have increased over the last years. The main products that
cause food allergy are: milk, eggs, peanuts, soy, wheat, fish, nuts, shellfish and fruit; many forms of
cross reactivity also prevail. The range of clinical symptoms varies widely, from rash to anaphylactic
shock. Diagnosis is based on careful history, skin tests and double blind placebo controlled oral
food challenges. This methodology will lead to establish the adequate form of treatment.Las reacciones adversas inducidas por alimentos, comprenden a todas aquellas manifestaciones
clínicas atribuidas a la ingesta de una sustancia alimenticia o aditivo asociado, y pueden
ser clasificadas sobre la base de los mecanismos implicados en su fisiopatología en alergia alimentaria
e intolerancia alimentaria. La alergia alimentaria es diagnosticada en la actualidad con mayor
frecuencia, pero su prevalencia no parecería haberse incrementado en los últimos años. Los principales
alimentos que la producen son: leche, huevo, maní, soja, trigo, pescado, nueces, mariscos y frutas,
existiendo muchas formas de reactividad cruzada. La variedad de síntomas clínicos es muy grande,
desde leves urticarias hasta el temido shock anafiláctico. El diagnóstico se basa en la historia clínica,
las pruebas cutáneas y el estudio de provocación a doble ciego y controlado con placebo, esto
llevará a instaurar la terapéutica adecuada
Relación entre índice de masa corporal y prevalencia de síntomas de asma en adultos jóvenes
La investigación ha tenido la siguiente planificación:
Objetivos: Valorar la relación entre el índice de masa corporal y la prevalencia de síntomas de asma
en una población de adultos jóvenes.
Sede: Universidad del Centro Educativo Latinoamericano. Rosario. Argentina.
Material y Métodos: Se reclutaron 311 estudiantes, 86.1% mujeres, con edades comprendidas entre
18 y 30 años (x = 20,80 ± 2,54) que asistían a la Universidad del Centro Educativo Latinoamericano
(UCEL). Los datos fueron recogidos durante mayo y junio del 2004, utilizando un cuestionario
modelo de ISAAC para asma y rinitis, así como cuestionarios sobre datos antropométricos, síntomas
de reflujo (RGE) y actividad física. El análisis estadístico se efectuó con EPI INFO.
Resultados: El promedio del índice de masa corporal (IMC) en los estudiantes fue de 20.83 kg/m2
para las mujeres y 24.02 kg/m2 para los varones (p<0,01). El 53.9% de los jóvenes manifestó haber
tenido síntomas de asma y/o rinitis alguna vez en la vida; el 18,7% presentó episodios de sibilancias
y el 40,2% síntomas nasales en los últimos 12 meses. El 43.5% de los estudiantes padecía síntomas
de reflujo y el 52,3% realizaba ejercicios dos o más días a la semana.
Los jóvenes con antecedentes de sibilancias y/o síntomas nasales mostraron un IMC promedio
mayor que los controles sanos (21.6 vs. 20.8 kg/m2, p<0,05). Los sujetos con síntomas de asma
en el último año tenían un IMC promedio superior a los que no sufrían de asma (22,4 vs. 21,0
kg/m2, p27 kg/m2) presentaron una prevalencia significativamente
mayor de síntomas de asma en la actualidad (OR: 3.53; IC95% 1.04 � 11.84; p<0.05),
en tanto que el bajo peso (IMC<19 kg/m2) parecería actuar como factor de protección (OR: 0.45;
IC95% 0.25 � 0.95; p<0.05).
El análisis estratificado mostró que tanto el RGE, como el sexo, la presencia de síntomas nasales
y la actividad física no actuaban como factores de confusión estadístico.
Conclusiones: Este estudio demuestra que en adultos jóvenes, seleccionados por su educación y
nivel socioeconómico, existe una asociación significativa entre sobrepeso y síntomas de asma.Objective: To evaluate the relation between body mass index and prevalence of asthma symptoms
in adults.
Setting: Centro Educativo Latinoamericano University. Rosario. Argentina.
Population: 311 students, 86,1% women, aged 18 and 30.
Method: Samples were obtained using the ISAAC as well as weight, height, reflux and physical activity
questionnaires. The statistical analysis was performed with EPI INFO.
Results: Students� mean body mass index (BMI) was 20.83 kg/m2 for women and 24.02 kg/m2 for
men (p<0,01). While 53.9% reported having symptoms of asthma or rhinitis, only 18.7% had presented
wheezing and 40.2% nasal symptoms over the past 12 months. There was evidence of reflux
symptoms among 43.5% of students. Only 52.3% exercised regularly twice or three times a week.
Students with wheezing or nasal symptoms showed a higher BMI than the control group (21.6 vs.
20.8 kg/m2, p<0,05). The subjects with wheezing over the past year had presented a higher BMI
than those without wheezing (22,4 vs. 21,0 kg/m2, p27
kg/m2) showed, at present, a significantly higher wheezing symptoms prevalence (OR: 3.53; IC95%
1.04 � 11.84; p<0.05) while the underweight students (IMC<19 kg/m2) showed a significantly lower
prevalence of wheezing symptoms (OR: 0.45; IC95% 0.25 � 0.95; p<0.05). Statistical analysis
showed that reflux, sex, presence of nasal symptoms and physical activity might not be confounding
factors.
Conclusion: This data suggest that in young adults, selected by education and economic level, there
is a significant relation between overweight and wheezing
Impacto económico del asma y la rinitis alérgica por cáscara de soja
Soybeans are the source of many critical man-made products. However, soybean transport and storage
in silos promotes the dispersion of fine pellet particles. There is substantial evidence of the direct
relation between respiratory exposure and sensitivity to soybean pellets as aeroallergens that cause
asthma and allergic rhinitis. This paper aims at analyzing the direct costs of asthma and allergic
rhinitis caused by soybean pellets only. Across-sectional analysis was carried out among 10 monosensitive
patients to soybean pellets including an evaluation of medical care expenses, diagnostic
methodology and preventive and rescue treatments. Separate measurements were taken for every
complaint. Acomparative assessment of these results was made with another sample of 20 patients
exhibiting asthma and allergic rhinitis to other aeroallergens. All patients were either from Rosario
or from neighboring towns in the humid plateau area. No significant differences were found
between costs for monosensitive individuals to soybean pellets and those sensitive to other aeroallergens agents. This is the first research to estimate the costs of an allergic disease caused by soybean
pellets. It is a health problem to be targeted in our country as a result of the ever-increasing cultivation
and trading opportunities of this oilseed.La soja es el grano del cual el hombre obtiene una gran cantidad de productos, con un
importante número de aplicaciones para su vida. El transporte de esta leguminosa y su almacenamiento
en silos genera la dispersión de finas partículas de polvo de su cáscara. Existen evidencias de
una relación directa entre exposición respiratoria y sensibilización frente a la cáscara de soja como
aeroalergeno productor de asma y rinitis. El objetivo del trabajo es analizar los costos directos del
asma y la rinitis alérgica causadas únicamente por cáscara de soja. Se realizó un estudio descriptivo
de corte transversal retrospectivo en el que se analizaron 10 pacientes monosensibles a cáscara de
soja en los cuales se valorizaron los costos de atención médica, metodología diagnóstica y terapéutica
preventiva y de rescate. Además se midieron por tipo de enfermedad. Se compararon estos resultados
con los de otra muestra de 20 pacientes que presentaron asma y rinitis alérgica a otros aeroalergenos.
Los pacientes de ambas muestras provenían de la ciudad de Rosario y ciudades vecinas
de la pampa húmeda. No se hallaron diferencias significativas en los costos entre el grupo de individuos
monosensibles a cáscara de soja y el de individuos sensibles a otros aeroalergenos. Este es el
primer estudio que valora los costos de la enfermedad alérgica por cáscara de soja, problema objetivo
de salud en nuestro país debido al explosivo auge comercial de dicha oleaginosa
Prevalence of late cutaneous reactivity to metabisulfites in patients with and without chronic eczema in Argentina
International consensus on (ICON) anaphylaxis
ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through 2014 by four allergy/immunology organizations. These guidelines concur with regard to the clinical features that indicate a likely diagnosis of anaphylaxis -- a life-threatening generalized or systemic allergic or hypersensitivity reaction. They also concur about prompt initial treatment with intramuscular injection of epinephrine (adrenaline) in the mid-outer thigh, positioning the patient supine (semi-reclining if dyspneic or vomiting), calling for help, and when indicated, providing supplemental oxygen, intravenous fluid resuscitation and cardiopulmonary resuscitation, along with concomitant monitoring of vital signs and oxygenation. Additionally, they concur that H1-antihistamines, H2-antihistamines, and glucocorticoids are not initial medications of choice. For self-management of patients at risk of anaphylaxis in community settings, they recommend carrying epinephrine auto-injectors and personalized emergency action plans, as well as follow-up with a physician (ideally an allergy/immunology specialist) to help prevent anaphylaxis recurrences. ICON: Anaphylaxis describes unmet needs in anaphylaxis, noting that although epinephrine in 1 mg/mL ampules is available worldwide, other essentials, including supplemental oxygen, intravenous fluid resuscitation, and epinephrine auto-injectors are not universally available. ICON: Anaphylaxis proposes a comprehensive international research agenda that calls for additional prospective studies of anaphylaxis epidemiology, patient risk factors and co-factors, triggers, clinical criteria for diagnosis, randomized controlled trials of therapeutic interventions, and measures to prevent anaphylaxis recurrences. It also calls for facilitation of global collaborations in anaphylaxis research. In addition to confirming the alignment of major anaphylaxis guidelines, ICON: Anaphylaxis adds value by including summary tables and citing 130 key references. It is published as an information resource about anaphylaxis for worldwide use by healthcare professionals, academics, policy-makers, patients, caregivers, and the public.Version of Recor
