323,153 research outputs found
Leanza, S., L'esegesi di Origene al libro dell'Ecclesiaste, 1975 [RESEÑA]
No full textReseña del libro de Sandro Leanza, «L'esegesi di Origene al libro dell'Ecclesiaste», publicado en 1975 por Edizione Parallelo.Peer reviewe
Extensive and permanent motoneuron loss in the rat lumbar spinal cord following neurotoxic lesion at birth: morphological evidence
No full textProjections to the supraoptic and paraventricular nuclei studied in the rat by means of retrograde fluorescent tracers (fast blue, nuclear yellow)
No full textRole of the ventromedial hypothalamus in the regulation of adenohypophyseal immunoreactive dynorphin in the rat
No full textSeptal grafts restore cognitive abilities and amyloid precursor protein metabolism
No full textCortical cholinergic loss and amyloidogenic processing of the -amyloid precursor protein (APP), may functionally interact in Alzheimer’s disease. However, it is still unknown whether biological restoration of regulatory cholinergic inputs affects APP metabolism in vivo.
Rats immunolesioned with 192 IgG-saporin exhibited severe acquisition deficits in place navigation that were paralleled by a dramatic loss of terminal cholinergic innervation and by marked changes in the regional expression of APP-like immunoreactivity. Moreover, in these animals, we observed a drastic reduction of soluble APP (sAPP) and a concomitant increase of the unsoluble, membrane-bound fraction (mAPP).
Notably, at about 6 months post-surgery, lesioned animals implanted with reinnervating cholinergic-rich septal tissue grafts exhibited fairly normal spatial navigation abilities, as well as cortical and hippocampal APP levels that were restored up to normal or near-normal values. APP levels correlated significantly with lesion- or graft-induced changes in cholinergic innervation density, and both these measures correlated with performance in the spatial navigation task.
Thus, integrity of ascending cholinergic inputs may be required to prevent amyloidogenic processing of APP in vivo and to modulate cognitive performance
Noradrenergic neurotransmission in the ventral spinal cord: basic characteristics and effects of denervating lesions, as studied in the awake rat by microdialysis.
No full textBranching serotonergic and non-serotonergic projections from caudal brainstem to the medial preoptic area and the lumbar spinal cord, in the rat.
No full textIntercomparison campaign of spectroradiometers for a correct estimation of solar spectral irradiance: results and potential impact on photovoltaic devices calibration
No full textThis paper describes the results of an intercomparison of spectroradiometers for global and direct normal incidence irradiance in the visible and near infrared spectral regions together with an assessment of the impact these results may have on the estimation of the short-circuit current (Isc) calibration of photovoltaic devices and on the spectral mismatch calculation. The intercomparison was conducted in the framework of the European project Apollon with the additional participation of external partners from the Italian project for the long-term monitoring of solar radiation for photovoltaics. Six institutions and six spectroradiometer systems, representing different technologies and manufacturers, were involved. Prior to the imtercomparison, all participating partners calibrated their own instrument(s) according to their usual procedures in order to verify the entire measuring and traceability chain. The difference in measured spectra shape and amplitude showed to have an impact on Isc calculation of less than 3% and less than 6% for single-junction and multi-junction devices, respectively. When only the shape of the spectra is considered, the specta mismatch ranges from 1.7% to 4.7% depending on the spectral response of the device
Colorectal cancer in aged patients. Toward the routine treatment through laparoscopic surgical approach
No full textAim. Colorectal cancer is one of the most common malignancies in general population. The incidence seems to be higher in older age. Surgery remains the treatment of choice and laparoscopic approach offers numerous benefits. We report our personal experience in elderly patients operated on for colorectal cancer with laparoscopic resection.Patients and methods. From January 2003 to September 2013, out of 160 patients aged 65 years or older and operated with minimally invasive techniques, 30 cases affected by colorectal cancer and operated on with laparoscopic approach were analyzed in this study.Results. Male/female ratio was 1.35 and mean age 72 years. Constipation, weight loss, anemia and rectal bleeding were the most commonly reported symptoms. Lesions involved descending-sigmoid colon in 53% of cases, rectum in 37% and ascending colon in 10%. Among laparoscopic colo-rectal operations laparoscopic left colectomy was the most frequently performed, followed by right colectomy, abdominoperineal resection and Hartmann procedure. Operative times ranged from 3 to 5 hours depending on surgical procedure performed. Mean hospital stay was 6 days (range 4-9). Conversion to open approach occurred only in a case of laparoscopic right colectomy (3%) for uncontrolled bleeding. A single case of mortality was reported. In two cases (7%) anastomotic leakage was observed, conservatively treated in one patient and requiring reoperation in the other one.Conclusions. Laparoscopic colorectal surgery is feasible and effective for malignancies in elderly population offering several advantages including immunologic and oncologic ones. However an experienced surgical team is essential in reducing risks and complications
Image-guided techniques for localization of pulmonary nodules during video-assisted thoracoscopic surgery lobectomy.
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