21,833 research outputs found
Case Study : Plínio Leal e Ana Leal, Lda.
No full textMestrado em FinançasNeste meu trabalho final do Master in Finance, decidi desenvolver um case study sobre uma empresa que tenha sido financiada pelo programa MODCOM. Este case study tem uma estrutura de 5 perguntas/problemas que estão relacionados com a função e papel desempenhado pela instituição IAPMEI, com a legislação e regras do programa MODCOM, com a situação/analise financeira da empresa "Plínio Leal & Ana Leal, lda" e com algumas questões e problemas que as PMEs possam ter de enfrentar. A primeira parte deste TFM, denominada de ?Descrição do caso?, apresenta a empresa em questão ("Plinio Leal & Ana Leal, lda"), o seu novo projecto, e também os mecanismos do incentivo promovido pelo IAPMEI para distinguir as PMEs com bons desempenhos e práticas. A segunda parte do case study apresenta então as já referidas questões, onde posteriormente serão divulgadas algumas das possíveis soluções. Essas soluções têm uma clara vertente financeira onde se objectiva uma avaliação da empresa e do seu novo projecto.In this Master Final Work I decided to develop a case study about a company that has been financed by the MODCOM program. This case study has a structure with five question/problems which are related with the function of the institution IAPMEI, with the legislation and rules of the MODCOM program, with the financial situation/analysis of the company "Plínio Leal & Ana Leal, lda." and with some issues and problems that the SME´s may face. The first part of the case study which has the name of "Case Description" presents the company involved ("Plinio Leal & Ana Leal, lda.") and its new project, and also the incentive mechanisms promoted by IAPMEI to distinguish SMEs with good standards and practices. The second part of the case study presents questions and case problems, which are afterwards solved and answered. Some of these questions have a clear financial perspective and meet the objective of evaluating the project and the company
Case Study : Plínio Leal e Ana Leal, Lda.
No full textMestrado em FinançasNeste meu trabalho final do Master in Finance, decidi desenvolver um case study sobre uma empresa que tenha sido financiada pelo programa MODCOM. Este case study tem uma estrutura de 5 perguntas/problemas que estão relacionados com a função e papel desempenhado pela instituição IAPMEI, com a legislação e regras do programa MODCOM, com a situação/analise financeira da empresa "Plínio Leal & Ana Leal, lda" e com algumas questões e problemas que as PMEs possam ter de enfrentar. A primeira parte deste TFM, denominada de ?Descrição do caso?, apresenta a empresa em questão ("Plinio Leal & Ana Leal, lda"), o seu novo projecto, e também os mecanismos do incentivo promovido pelo IAPMEI para distinguir as PMEs com bons desempenhos e práticas. A segunda parte do case study apresenta então as já referidas questões, onde posteriormente serão divulgadas algumas das possíveis soluções. Essas soluções têm uma clara vertente financeira onde se objectiva uma avaliação da empresa e do seu novo projecto.In this Master Final Work I decided to develop a case study about a company that has been financed by the MODCOM program. This case study has a structure with five question/problems which are related with the function of the institution IAPMEI, with the legislation and rules of the MODCOM program, with the financial situation/analysis of the company "Plínio Leal & Ana Leal, lda." and with some issues and problems that the SME´s may face. The first part of the case study which has the name of "Case Description" presents the company involved ("Plinio Leal & Ana Leal, lda.") and its new project, and also the incentive mechanisms promoted by IAPMEI to distinguish SMEs with good standards and practices. The second part of the case study presents questions and case problems, which are afterwards solved and answered. Some of these questions have a clear financial perspective and meet the objective of evaluating the project and the company
Case Study : Plínio Leal e Ana Leal, Lda.
No full textMestrado em FinançasNeste meu trabalho final do Master in Finance, decidi desenvolver um case study sobre uma empresa que tenha sido financiada pelo programa MODCOM. Este case study tem uma estrutura de 5 perguntas/problemas que estão relacionados com a função e papel desempenhado pela instituição IAPMEI, com a legislação e regras do programa MODCOM, com a situação/analise financeira da empresa "Plínio Leal & Ana Leal, lda" e com algumas questões e problemas que as PMEs possam ter de enfrentar. A primeira parte deste TFM, denominada de ?Descrição do caso?, apresenta a empresa em questão ("Plinio Leal & Ana Leal, lda"), o seu novo projecto, e também os mecanismos do incentivo promovido pelo IAPMEI para distinguir as PMEs com bons desempenhos e práticas. A segunda parte do case study apresenta então as já referidas questões, onde posteriormente serão divulgadas algumas das possíveis soluções. Essas soluções têm uma clara vertente financeira onde se objectiva uma avaliação da empresa e do seu novo projecto.In this Master Final Work I decided to develop a case study about a company that has been financed by the MODCOM program. This case study has a structure with five question/problems which are related with the function of the institution IAPMEI, with the legislation and rules of the MODCOM program, with the financial situation/analysis of the company "Plínio Leal & Ana Leal, lda." and with some issues and problems that the SME´s may face. The first part of the case study which has the name of "Case Description" presents the company involved ("Plinio Leal & Ana Leal, lda.") and its new project, and also the incentive mechanisms promoted by IAPMEI to distinguish SMEs with good standards and practices. The second part of the case study presents questions and case problems, which are afterwards solved and answered. Some of these questions have a clear financial perspective and meet the objective of evaluating the project and the company
A new species of Supramontana Carbayo & Leal-Zanchet (Platyhelminthes, Continenticola, Geoplanidae) from the Interior Atlantic Forest
Get PDFNegrete, Lisandro, Leal-Zanchet, Ana Maria, Brusa, Francisco (2014): A new species of Supramontana Carbayo & Leal-Zanchet (Platyhelminthes, Continenticola, Geoplanidae) from the Interior Atlantic Forest. Zootaxa 3753 (2): 177-186, DOI: 10.11646/zootaxa.3753.2.
Pasipha backesi Leal-Zanchet, Rossi & Seitenfus, sp. nov.
No full textPasipha backesi Leal-Zanchet, Rossi & Seitenfus, sp. nov. Pasipha sp. 1: Leal-Zanchet & Carbayo, 2000 Pasipha sp. 1: Leal-Zanchet & Baptista, 2009 Pasipha sp. 2: Leal-Zanchet et al., 2009 Pasipha sp. 1: Leal-Zanchet et al., 2011 Etymology: the specific name is in honor of Prof. Dr. Albano Backes and his worthy contribution to the knowledge of the ecology of the Araucaria Forest. Type-material. Holotype: MZUSP PL. 1201: leg. M. Cardoso, 31. July 1998, São Francisco de Paula, RS, Brazil—anterior tip: transverse sections on 12 slides; anterior region at the level of the ovaries: sagittal sections on 15 slides; prepharyngeal region: transverse sections on 10 slides; pharynx: sagittal sections on 15 slides; copulatory apparatus: sagittal sections on 19 slides; Paratypes: MZU PL. 127: leg. F. Carbayo, 19. October 1996, São Francisco de Paula, RS, Brazil—prepharyngeal region: transverse sections on 8 slides; pharynx and copulatory apparatus: sagittal sections on 39 slides; MZU PL. 128: leg. R. Murowaniecki, 10. July 1998, São Francisco de Paula, RS, Brazil—anterior region at the level of the ovaries: horizontal sections on 7 slides; pre-pharyngeal region: transverse sections on 5 slides; pharynx: sagittal sections on 9 slides; copulatory apparatus: sagittal sections on 14 slides; MZU PL. 129: leg. L.B. Matos, 0 5. October 2003, São Francisco de Paula, RS, Brazil—anterior tip: transverse sections on 19 slides; pre-pharyngeal region: transverse sections on 6 slides; pharynx: sagittal sections on 11 slides; copulatory apparatus: horizontal sections on 8 slides. Diagnosis: Dorsum brown with yellowish median stripe, bordered by dark-brown to black paramedian stripes; eyes dorsal, with clear halos; glandular border with three cell types; mc:h, 18 %– 19 %; pharynx cylindrical; esophagus conspicuous; esophagus: pharynx ratio, 17 %– 20 %; anteriormost testes posterior to ovaries; most posterior testes near root of pharynx; sperm ducts opening dorsally displaced into lateral walls of proximal region of vesicle; prostatic vesicle globose, extrabulbar, consisting of two distinct regions: a forked ental region and a large unforked ectal region; ejaculatory duct sinuous; male atrium long, highly folded, with two main regions; ovovitelline ducts emerging dorsally, but laterally displaced, from posterior half of ovaries, and uniting below female atrium; common glandular ovovitelline duct posteriorly directed, slightly ascendent; female canal almost vertical; female atrium oval-elongate, highly folded; length of male atrium, about two times that of female atrium; gonopore canal slightly posteriorly inclined; male and female atria with independent musculatures; no folds separating male and female atria. Type-locality: São Francisco de Paula, state of Rio Grande do Sul (RS), Brazil. Distribution: Rio Grande do Sul (São Francisco de Paula), Brazil. TABLE I. Measurements, in mm, of specimens of Pasipha backesi Leal-Zanchet, Rossi & Seitenfus, sp. nov. –: not measured; *: After fixation; DG: distance of gonopore from anterior end; DM: distance of mouth from anterior end; DMG: distance between mouth and gonopore; DPVP: distance between prostatic vesicle and pharyngeal pouch. The numbers given in parentheses represent the position relative to body length.Published as part of Leal-Zanchet, Ana Maria, Rossi, Ilana, Seitenfus, Ana Lúcia Ramos & Alvarenga, Juliana, 2012, Two new species of land flatworms and comments on the genus Pasipha Ogren & Kawakatsu, 1990 (Platyhelminthes: Continenticola), pp. 1-21 in Zootaxa 3583 on pages 2-3, DOI: 10.5281/zenodo.28308
Tecnologías y aprendizaje servicio: un cambio de concepción
No full textLeal Acedo, Ana Lucía; director de proyecto: Tello Díaz-Maroto, Inmaculada2021-2022Máster Universitario en Tecnología Educativa y Competencias Digitales DocentesFacultad de Estudios Sociales y Lenguas Aplicada
Isotriphora tigrina Fernandes, Pimenta & Leal 2013
No full texttigrina, Isotriphora Fernandes, Pimenta & Leal, 2013 Isotriphora tigrina Fernandes, Pimenta & Leal, 2013: 8–9 (figs 7–8, 39–44). Gastropoda, Triphoridae Paratypes (3 spc): MZSP 105154. Locality: Brazil, Trindade Island, Vitória-Trindade Chain, 20°30' S, 29°19' W, MD55 sta. DC59, 52– 60 m depth (type locality). Collectors: P. Bouchet, J.H. Leal and B. Métivier. Preservation: Dry.Published as part of Cavallari, Daniel C., Dornellas, Ana Paula S. & Simone, Luiz Ricardo L., 2016, Second annotated list of type specimens of molluscs deposited in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-59 in European Journal of Taxonomy 213 on page 50, DOI: 10.5852/ejt.2016.213, http://zenodo.org/record/384012
Apego y Trastorno Límite de la Personalidad: Una Revisión Sistemática
No full textLeal Vélez de Mendizábal, Ana; director de proyecto: Perestelo Pérez, Lilisbeth2020-2021Máster Universitario en Psicología General SanitariaFacultad de Medicin
Pasipha brevilineata Leal-Zanchet, Rossi & Alvarenga, sp. nov.
No full textPasipha brevilineata Leal-Zanchet, Rossi & Alvarenga, sp. nov. Pasipha sp. 3: Leal-Zanchet & Carbayo, 2000 Pasipha sp. 3: Leal-Zanchet & Baptista, 2009 Pasipha sp. 2: Leal-Zanchet et al., 2009 Pasipha sp. 3: Leal-Zanchet et al., 2011 Etymology: the specific name refers to the thin (=brevi) median stripe (=lineata) over the dorsum. Type-material. Holotype: MZUSP PL. 1202: coll. A. M. Leal-Zanchet, 0 8. September 2000, São Francisco de Paula, RS, Brazil—anterior tip in two fragments: transverse sections on 20 slides; anterior region at the level of the ovaries: sagittal sections on 10 slides; pre-pharyngeal region: transverse sections on 6 slides; pharynx: sagittal sections on 10 slides; copulatory apparatus: sagittal sections on 19 slides; Paratypes: MZU PL. 130: leg. F. Carbayo, 14. January 1998, São Francisco de Paula, RS, Brazil—prepharyngeal region: transverse sections on 10 slides; pharynx and copulatory apparatus: sagittal sections on 13 slides; MZU PL. 131: leg. M. Cardoso, 0 4. May 1998, São Francisco de Paula, RS, Brazil—anterior tip: horizontal sections on 5 slides; pre-pharyngeal region: transverse sections on 11 slides; pharynx: sagittal sections on 16 slides; copulatory apparatus: sagittal sections on 15 slides; MZU PL. 132: leg. L. S. Teixeira, 0 8. June 1998, São Francisco de Paula, RS, Brazil—anterior region at the level of the ovaries in two fragments: horizontal sections on 15 slides; pre-pharyngeal region: transverse sections on 4 slides; pharynx: sagittal sections on 7 slides; copulatory apparatus: sagittal sections on 11 slides; MZU PL. 133: coll. A. M. Leal-Zanchet, 14. January 1999, São Francisco de Paula, RS, Brazil—preserved in ethanol 70 º; MZU PL. 134: leg. M. Cardoso, 23. March 1999, São Francisco de Paula, RS, Brazil—preserved in clove oil; MZU PL. 135: leg. V. Baptista, 27. May 2004, São Francisco de Paula, RS, Brazil—anterior tip: transverse sections on 20 slides; pre-pharyngeal region: transverse sections on 10 slides; pharynx and copulatory apparatus: sagittal sections on 17 slides; MZU PL. 136: leg. J. Alvarenga, 0 5. August 2005, São Francisco de Paula, RS, Brazil—copulatory apparatus: horizontal sections on 13 slides; MZU PL. 137: leg. L.B. Matos, 0 5. August 2005, São Francisco de Paula, RS, Brazil—copulatory apparatus: sagittal sections on 10 slides. Diagnosis: Dorsum black or dark-brown; median stripe pale yellow to grayish, thin and sometimes interrupted, becoming whitish and wider next to posterior tip; eyes dorsal with clear halos; glandular border with three cell types; mc:h, 17 %- 19 %; pharynx cylindrical; esophagus conspicuous; esophagus: pharynx ratio, 27 %- 37 %; anteriormost testes posterior to ovaries; most posterior testes near root of pharynx; sperm ducts opening into end of proximal region of vesicle; prostatic vesicle, mainly globose, extrabulbar with two distinct regions: a forked, laterally expanded and ventrally disposed ental region and a large unforked ectal region; ejaculatory duct sinuous; male atrium long, intensely folded, with two main regions; ovovitelline ducts emerging dorsally from end of posterior half of ovaries, uniting ventrally to the female atrium; common glandular ovovitelline duct almost vertical, slightly anteriorly arched; female canal posteriorly directed and slightly recurved; female atrium oval-elongate, highly folded; length of male atrium, approximately two times that of female atrium; gonopore canal slightly posteriorly inclined; male and female atria with independent musculatures; dorsal elongated fold separating male and female atria. Type-locality: São Francisco de Paula, state of Rio Grande do Sul (RS), Brazil. Distribution: Rio Grande do Sul (São Francisco de Paula), Brazil. TABLE III. Measurements, in mm, of specimens of Pasipha brevilineata Leal-Zanchet, Rossi & Alvarenga, sp. nov. -: not measured; --: gonopore absent; *: After fixation; DG: distance of gonopore from anterior end; DM: distance of mouth from anterior end; DMG: distance between mouth and gonopore; DPVP: distance between prostatic vesicle and pharyngeal pouch. The numbers given in parentheses represent the position relative to body length.Published as part of Leal-Zanchet, Ana Maria, Rossi, Ilana, Seitenfus, Ana Lúcia Ramos & Alvarenga, Juliana, 2012, Two new species of land flatworms and comments on the genus Pasipha Ogren & Kawakatsu, 1990 (Platyhelminthes: Continenticola), pp. 1-21 in Zootaxa 3583 on pages 9-10, DOI: 10.5281/zenodo.28308
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility
No full text14 pags., 7 figs., 3 tabs.Hybrids of RNA with arabinonucleic acids 2′F-ANA and ANA have very similar structures but strikingly different thermal stabilities. We now present a thorough study combining NMR and other biophysical methods together with state-of-the-art theoretical calculations on a fully modified 10-mer hybrid duplex. Comparison between the solution structure of 2′F-ANA•RNA and ANA•RNA hybrids indicates that the increased binding affinity of 2′F-ANA is related to several subtle differences, most importantly a favorable pseudohydrogen bond (2′F-purine H8) which contrasts with unfavorable 2′-OH-nucleobase steric interactions in the case of ANA. While both 2′F-ANA and ANA strands maintained conformations in the southern/eastern sugar pucker range, the 2′F-ANA strand's structure was more compatible with the A-like structure of a hybrid duplex. No dramatic differences are found in terms of relative hydration for the two hybrids, but the ANA•RNA duplex showed lower uptake of counterions than its 2′F-ANA•RNA counterpart. Finally, while the two hybrid duplexes are of similar rigidities, 2′F-ANA single strands may be more suitably preorganized for duplex formation. Thus the dramatically increased stability of 2′F-ANA•RNA and ANA•RNA duplexes is caused by differencesin at least four areas, of which structure and pseudohydrogen bonding are the most important. © The Author(s) 2010. Published by Oxford University Press.Spanish Ministerio de Ciencia e Innovacion (grants
CTQ2007-68014-C02-02 to CG and BIO2009-10964 to
MO); Fundacion Marcelino Botin (grant to MO);
Canadian Institutes for Health Research (grant to
M.J.D.); Natural Sciences and Engineering Research
Council of Canada (postgraduate scholarship to
J.K.W.). Funding for open access charge: Canadian
Institutes for Health Research
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