1,720,995 research outputs found
Reduced stretch-induced delayed force response and maintained Frank-Starling mechanism in failing human myocardium
No full textp38 MAP kinase and oxygen radicals mediate progressive right ventricular force decline after acute stretch
No full textReduced stretch-induced delayed force response and maintained Frank-Starling mechanism in failing human myocardium
No full text
p38 MAP kinase and oxygen radicals mediate progressive right ventricular force decline after acute stretch
No full text
Dynamic imaging of colloidal-crystal nanostructures at 200 frames per second.
No full textThe dynamic noninvasive imaging of colloidal nanostructures has been precluded by the diffraction-limited resolution of (confocal) light microscopy Using Fast Stimulated Emission Depletion (STED) microscopy, we demonstrate the ability to resolve the formation of a colloidal crystal (monolayer) from particles of 200 nm size, where the voids in the crystal are as small as 30 nm With a temporal resolution or 5 ms, we exemplify the technique by visualizing the annealing of potential point detects (luring the formation of the colloidal crystal
Dynamic far-field fluorescence nanoscopy
No full textWe demonstrate far-field fluorescence microscopy with subdiffraction resolution of rapidly moving nanoparticles. Fast recording on the nanoscale is accomplished by merging rapid beam scanning with stimulated emission depletion (STED) microscopy. By recording at 80 frames per second with a focal spot area which is 9-10-fold smaller than the diffraction limit, the Brownian motion of a dense suspension of 36 nm particles was revealed. Individual particles were localized with similar to 20nm accuracy, while automated particle tracking revealed their distribution of speeds. The first combination of rapid image acquisition with a diffraction-unlimited far-field microscopy concept heralds a large range of possible applications of dynamic fluorescence nanoscopy in various fields, including in biology
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