160 research outputs found
Finite element implementation of an anisotropic remodelling law for cerebral aneurysm development.
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Prototipare esperienze. Il design e l'intelligenza della forma
No full textAlbeChe ne è del disegno oggi? Dove lo possiamo riconoscere? Cosa è accaduto nel corso della storia, da quando il disegno si è affermato nel Rinascimento come pratica intellettuale, strumento essenziale del pensiero visivo? Dopo la riproducibilità tecnica e la rivoluzione digitale, in che modo, attraverso quali strategie, il disegno può essere ancora strumento di conoscenza e di interpretazione della realtà? Il volume promuove una riflessione sul tema, seguendo i percorsi compiuti dal design e dalle arti, all'industria culturale e all'estetica, per interrogarci sul valore attuale del disegno come strumento variabile per differenti processi culturali, attraverso i saggi di: Alberto Abruzzese, Sandro Bernardi, Valeria Bruni, Massimo Carboni, Marco Cianchi, Giovanni Fiorentino, Gino Frezza, Francesco Galluzzi, Andrea Granchi, Salvatore Iaconesi, Lorenzo Imbesi, Anna Luppi, Roberto Maragliano, Samatha Passamani, Ruggero Pierantoni, Cristina Reggio, Carlo Siiti, Stefano Socci, Franco Speroni, Tommaso Tozzi, Laura Vecere, Alessandra Vettori.What is design today? How can we recognize it? What happened throughout history, since design emerged as an intellectual practice and an essential tool of visual thinking in the Renaissance? After the technical reproducibility and the digital revolution, how and through what strategies, the design may still be an instrument of knowledge and interpretation of reality? The book is opening a reflection on the topic, following the paths made by design and the arts, by the industry of culture and aesthetics, to wonder about the actual value of the design as a tool for different cultural processes, through the essays of the following authors: Alberto Abruzzese, Sandro Bernardi, Valeria Bruni, Massimo Carboni, Marco Cianchi, Giovanni Fiorentino, Gino Frezza, Francesco Galluzzi, Andrea Granchi, Salvatore Iaconesi, Lorenzo Imbesi, Anna Luppi, Roberto Maragliano, Samatha Passamani, Ruggero Pierantoni, Cristina Reggio, Carlo Siiti, Stefano Socci, Franco Speroni, Tommaso Tozzi, Laura Vecere, Alessandra Vettori
An anisotropic model for tissue growth and remodeling during early development of cerebral aneurysms
No full textThis paper presents a constitutive model for predicting the time-dependent response of growing aneurysms during their early development, with particular regards to cerebral aneurysms. The adaptive process is interpreted as the result of two competitive mechanisms: a change in the reference length of collagen fibers and a change in the collagen fiber density. The elastic behavior, based on the definition of anisotropic strain energy function, is extended to the growth regime by means of a suitably developed constitutive framework based on the multiplicative decomposition of the deformation gradient into elastic and inelastic components defined for the fibers. Rate equations ruling the time evolution of the fiber reference length and of the fiber density are introduced. The constitutive parameters for the passive behavior of cerebral arterial walls are identified by fitting experimental results taken from the literature.
Two representative numerical examples are presented to illustrate the capability of the model of simulating the time evolution of saccular as well as fusiform aneurysms to a perturbation of the homeostatic (physiologic) state. A simplified geometrical model is used for the two examples.
The results have shown that the two mechanisms, the change in fiber reference length and the fiber density change, have opposite effects on the stability of the tissue growth. Unstable growth is obtained even for a small perturbation of the reference state in the cases in which the mechanism affecting the fiber density is not sufficiently strong
A constituent-based computational model for vascular remodelling of a growing cerebral aneurysm
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