515 research outputs found
Studies of nucleon-gold collisions at 200 GeV per nucleon pair using tagged d+Au interactions
No full textThesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 2006.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Includes bibliographical references (p. 201-212).The spectra of charged hadrons produced near mid-rapidity in d+Au, p+Au and n+Au collisions at - = 200 GeV are presented as a function of transverse momentum and centrality. These measurements were performed using the PHOBOS detector at the Relativistic Heavy Ion Collider (RHIC). Nucleon-nucleus interactions were extracted from the d+Au data by identifying the deuteron spectators. The deuteron spectators were measured using two calorimeters; one that detected forward-going single neutrons and a newly installed calorimeter that detected forward-going single protons. The large suppression of high-pr hadron production in central Au+Au interactions relative to a naive superposition of p+p collisions has been interpreted as evidence of partonic energy loss in a dense medium. This interpretation is founded upon the absence of such suppression in the yield of d+Au collisions. The validity of using d+Au interactions in place of a nucleon-nucleus reference is tested. It is shown that hadron production in d+Au agrees with a simple binary collision scaling of hadron production in p+Au. An ideal reference for Au+Au collisions is constructed using a weighted combination of p+Au and n+Au yields and is found to be similar to the d+Au reference.(cont.) Further, hadron production in p+Au interactions is compared to that of n+Au interactions. The single charge difference between a p+Au and a n+Au collision allows for a unique study of the ability of the interaction to transport the proton from the initial deuteron to mid-rapidity. However, no asymmetry between the positively and negatively charged hadron spectra of p+Au and n+Au interactions is observed at (qr) = 0.8. Collision centrality was determined using several different observables, including those based on the multiplicity in different regions of pseudorapidity and those based on the amount of nuclear spectator material. It is shown that measurements made on small collision systems in the mid-rapidity region are biased by centrality variables based on the mid-rapidity multiplicity. Despite this bias, a smooth evolution with centrality is observed in the Cronin enhancement of hadrons produced in d+Au collisions. It is shown that this smooth progression is independent of the choice of centrality variable when centrality is parametrized by the multiplicity measured near mid-rapidity.by Corey Reed.Ph.D
Unresolved splenomegaly in recently resettled Congolese refugees — Multiple states, 2015–2018
No full textZambrano, Laura D.; Samson, Olivia; Phares, Christina; Jentes, Emily; Weinberg, Michelle; Goers, Matthew; Kachur, Patrick; McDonald, Robert; Morawski, Bozena; Njuguna, Henry; Bakhsh, Yasser; Laws, Rebecca; Peak, Corey; Iverson, Sally Ann; Bezold, Carla; Allkhenfr, Hayder; Horth, Roberta; Yang, Jun; Miller, Susan; Kacka, Michael; Davids, Abby; Mortimer, Margaret; Khan, Nomana; Stauffer, William; Marano, Nina. (2018). Unresolved splenomegaly in recently resettled Congolese refugees — Multiple states, 2015–2018. Retrieved from the University Digital Conservancy, 10.15585/MMWR.MM6749A2
From Mendel to me: Constructing genetics knowledge through historical problem-based learning
No full textJournal Articl
Peptide-Grafted Nontoxic Cyclodextrins and Nanoparticles against Bacteriophage Infections
No full textOne of the biggest threats for bacteria-based bioreactors in the biotechnology industry is infections caused by bacterial viruses called bacteriophages. More than 70% of companies admitted to encountering this problem. Despite phage infections being such a dangerous and widespread risk, to date, there are no effectiv e methods to avoid them. Here we present a peptide-grafted compounds that irreversibly deacti-vate bacteriophages and remain safe for bacteria and mammalian cells. The active compounds consist of a core (cyclodextrin or gold nanoparticle) coated with a hydrophobic chain terminated with a peptide selective for bacteriophages. Such peptides were selected via a phage display technique. This approach enables irreversible deactivation of the wide range of T-like phages (including the most dangerous in phage infections, phage T1) at 37 degrees C in 1 h. We show that our compounds can be used directly inside the environment of the bioreactor, but they are also a safe additive to stocks of antibiotics and expression inducers (such as isopropyl beta-D-1-thiogalactopyranoside, i.e., IPTG) that cannot be autoclaved and are a common source of phage infections.SUNMI
Ceftaroline: A cephalosporin with expanded Gram-positive activity
No full textInfections caused by resistant Gram-positive pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) are now posing a major health risk for patients in hospital and community settings. There is a need to evaluate new antibiotics that would offer reliable clinical efficacy combined with a favorable safety profile for the treatment of such infections. Ceftaroline is a new member of the cephalosporin class of antibiotics with expanded activity against Gram-positive pathogens such as MRSA, vancomycin-intermediate S. aureus, vancomycin-resistant S. aureus and multidrug-resistant Streptococcus pneumoniae, while retaining good activity against common Gram-negative organisms. Phase II and III studies have shown ceftaroline to be an effective and well-tolerated treatment-tor complicated skin and skin-structure infections compared with standard therapy. Trials are ongoing in the treatment of community-acquired pneumonia. © 2009 Future Medicine.Andes D, 2006, ANTIMICROB AGENTS CH, V50, P1376, DOI 10.1128-AAC.50.4.1376-1383.2006; [Anonymous], 2006, M100S16 CLSI; BARRY PM, 2008, 48 ANN INT C ANT AG; Bo G, 2000, CLIN MICROBIOL INFEC, V6, P6; COREY GR, 2008, 48 ANN INT C ANT AG; Fenoll A, 2008, ANTIMICROB AGENTS CH, V52, P4209, DOI 10.1128-AAC.00712-08; Ge Y, 2006, 46 ANN INT C ANT AG; Ge Y, 2008, ANTIMICROB AGENTS CH, V52, P3398, DOI 10.1128-AAC.00149-08; Hinshaw RR, 2008, 48 ANN INT C ANT AG; Iizawa Yuji, 2004, Journal of Infection and Chemotherapy, V10, P146; Ishikawa T, 2003, BIOORGAN MED CHEM, V11, P2427, DOI 10.1016-S0968-0896(03)00126-3; JACQUELINE C, 2008, 48 ANN INT C ANT AG; JACQUELINE C, 2006, 46 ANN INT C ANT AG; Jacqueline C, 2007, ANTIMICROB AGENTS CH, V51, P3397, DOI 10.1128-AAC.01242-06; Kanafani ZA, 2006, ENFERM INFEC MICR CL, V24, P182, DOI 10.1157-13086552; Mariani PG, 2006, J ANTIMICROB CHEMOTH, V58, P481, DOI 10.1093-jac-dkl256; MOISE PA, 2000, ANTIMICROB AGENTS S1, V16, pS31; Mushtaq S, 2007, J ANTIMICROB CHEMOTH, V60, P300, DOI 10.1093-jac-dkm150; Riccobene T, 2008, 48 ANN INT C ANT AG; Sader HS, 2008, ANTIMICROB AGENTS CH, V52, P1153, DOI 10.1128-AAC.01351-07; Sader HS, 2005, ANTIMICROB AGENTS CH, V49, P3501, DOI 10.1128-AAC.49.8.3501-3512.2005; Sakoulas G, 2004, J CLIN MICROBIOL, V42, P2398, DOI 10.1128-JCM.42.6.2398-2402.2004; SARAVOLATZ LD, 2008, 48 ANN INT C ANT AG; SCHAADT RD, 2007, 47 ANN INT C ANT AG; Silverman JA, 2005, J INFECT DIS, V191, P2149, DOI 10.1086-430352; Talbot GH, 2007, ANTIMICROB AGENTS CH, V51, P3612, DOI 10.1128-AAC.00590-07; Tenover FC, 2007, CLIN INFECT DIS, V44, P1208, DOI 10.1086-513203; VIDAILLAC C, 2008, 48 ANN INT C ANT AG; Villegas-Estrada A, 2008, J AM CHEM SOC, V130, P9212, DOI 10.1021-ja8029448; Woods CW, 2004, CLIN INFECT DIS, V38, P1188, DOI 10.1086-383027; XIONG YQ, 2007, 47 ANN INT C ANT AG24181
Franklin D. Roosevelt: The Media, His Physical Image, and Teaching Implications
No full textThis thesis consists of three distinct chapters, each with a focus on the general theme of Franklin Delano Roosevelt, the media, and his image. Chapter I is a historiography that traces the scholarly discussion of Roosevelt and the media from the late 1970s until the early 21st century. It argues that there was a shift in research that occurred in the 1980s. Where scholarship originally focused intently on how FDR used the media to run the country, it transitioned towards an exclusive concentration on how he used the media to minimize the public’s perception of his disability. Chapter II consists of primary research with two objectives. First, it exposes how FDR projected an image of health, activity, and masculinity in order to inspire confidence in his ability to lead during his time period; and second, it compares that public image to the one that has evolved over the past 68 years since his death—particularly in relation to his disability. The author analyzes a combination of memorials, museums, and historic sites that focus on FDR to expose society’s contemporary public image of Franklin Roosevelt. The author discovers that FDR’s contemporary public image is a complex one, filled with some sites that are reluctant to embrace his paralysis and some that do so passionately; nevertheless, it appears that a general trend is developing toward accepting the role of Roosevelt’s disability in his public image. Chapter III focuses on making the information in Chapter I and II applicable to teaching. It identifies four evidence-based teaching strategies and discusses them in relation to six destinations. Each of these destinations will facilitate lessons and fieldtrips targeted at fostering deeper level thinking while studying Franklin Roosevelt’s use of the media and the manipulation of his image. Chapter III concludes with a list of material resources that would supplement these destinations including films, digital resources, CDs, and primary and secondary literature.SUNY BrockportEducation and Human DevelopmentMaster of Science in Education (MSEd)Education and Human Development Master's These
The Art Dealer and the Devil: Remarks on the Relationship of Elia Volpi and Wilhelm von Bode
No full textThe essay focus on the relationship between the powerful Wilhelm von Bode, creator of the Kaiser Friedrich Museum in Berlin, and the Florentine art Dealer Elia Volpi, in the historic context of the end of 18 and beginning of 19 century. The text explores connections among Florentine antiquarians, trading strategies and relationships between them, the museum curators and the decadence of noble family
StarnsSupplementalMaterial – Supplemental material for Assessing Theoretical Conclusions With Blinded Inference to Investigate a Potential Inference Crisis
No full textSupplemental material, StarnsSupplementalMaterial for Assessing Theoretical Conclusions With Blinded Inference to Investigate a Potential Inference Crisis by Jeffrey J. Starns, Andrea M. Cataldo, Caren M. Rotello, Jeffrey Annis, Andrew Aschenbrenner, Arndt Bröder, Gregory Cox, Amy Criss, Ryan A. Curl, Ian G. Dobbins, John Dunn, Tasnuva Enam, Nathan J. Evans, Simon Farrell, Scott H. Fraundorf, Scott D. Gronlund, Andrew Heathcote, Daniel W. Heck, Jason L. Hicks, Mark J. Huff, David Kellen, Kylie N. Key, Asli Kilic, Karl Christoph Klauer, Kyle R. Kraemer, Fábio P. Leite, Marianne E. Lloyd, Simone Malejka, Alice Mason, Ryan M. McAdoo, Ian M. McDonough, Robert B. Michael, Laura Mickes, Eda Mizrak, David P. Morgan, Shane T. Mueller, Adam Osth, Angus Reynolds, Travis M. Seale-Carlisle, Henrik Singmann, Jennifer F. Sloane, Andrew M. Smith, Gabriel Tillman, Don van Ravenzwaaij, Christoph T. Weidemann, Gary L. Wells, Corey N. White and Jack Wilson in Advances in Methods and Practices in Psychological Science</p
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