1,721,140 research outputs found
sj-docx-1-jop-10.1177_02698811231221153 – Supplemental material for Neural correlates of episodic memory decline following electroconvulsive therapy: An exploratory functional magnetic resonance imaging study
No full textSupplemental material, sj-docx-1-jop-10.1177_02698811231221153 for Neural correlates of episodic memory decline following electroconvulsive therapy: An exploratory functional magnetic resonance imaging study by Jeff Zarp Petersen, Julian Macoveanu, Alexander Tobias Ysbæk-Nielsen, Lars Vedel Kessing, Martin Balslev Jørgensen and Kamilla Woznica Miskowiak in Journal of Psychopharmacology</p
sj-docx-2-jop-10.1177_02698811231221153 – Supplemental material for Neural correlates of episodic memory decline following electroconvulsive therapy: An exploratory functional magnetic resonance imaging study
No full textSupplemental material, sj-docx-2-jop-10.1177_02698811231221153 for Neural correlates of episodic memory decline following electroconvulsive therapy: An exploratory functional magnetic resonance imaging study by Jeff Zarp Petersen, Julian Macoveanu, Alexander Tobias Ysbæk-Nielsen, Lars Vedel Kessing, Martin Balslev Jørgensen and Kamilla Woznica Miskowiak in Journal of Psychopharmacology</p
sj-docx-1-jop-10.1177_02698811241237869 – Supplemental material for Effects of erythropoietin on cognitive impairment and prefrontal cortex activity across affective disorders: A randomized, double-blinded, placebo-controlled trial
No full textSupplemental material, sj-docx-1-jop-10.1177_02698811241237869 for Effects of erythropoietin on cognitive impairment and prefrontal cortex activity across affective disorders: A randomized, double-blinded, placebo-controlled trial by Julian Macoveanu, Jeff Zarp Petersen, Johanna Mariegaard, Andreas Elleby Jespersen, Katrine Cramer, Caroline Fussing Bruun, Helle Østergaard Madsen, Martin Balslev Jørgensen, Maj Vinberg, Patrick M Fisher, Gitte Moos Knudsen, Ida Hageman, Hannelore Ehrenreich, Lars Vedel Kessing and Kamilla Woznica Miskowiak in Journal of Psychopharmacology</p
Smartphone-based self-monitoring in bipolar disorder: evaluation of usability and feasibility of two systems
Full text linkAbstract Background The aims of the present multicenter pilot study were to examine the feasibility and usability of two different smartphone-based monitoring systems (the Pulso system and the Trilogis-Monsenso system) from two IT companies in patients with bipolar disorder, developed and selected to be testes as a part of a European Union funded Pre-Commercial Procurement (the NYMPHA-MD project). Methods Patients with bipolar disorder (ICD-10), > 18 years of age during a remitted, partial remitted or mild to moderate depressive state (HDRS-17 < 25) from Italy, Spain and Denmark were included. Patients were randomized 1:1 to the use of one of two smartphone-based monitoring systems. The randomization was stratified according to study location (Italy, Spain, Denmark) and all patients were followed for a 4 weeks study period. Usability and feasibility were evaluated using the Computer System Usability Questionnaire, and the Usefulness, Satisfaction, and Ease of use Questionnaire. Results A total of 60 patients aged 18–69 years with bipolar disorder (ICD-10) recruited from Italy, Spain, Denmark were included—59 patients completed the study. In Denmark, the patients evaluated the Trilogis-Monsenso system with a statistically significant higher usability compared with the Pulso system. In Italy and Spain, the patients evaluated no statistically significant difference between the two systems in any of the categories, except for the usefulness category favoring the Trilogis-Monsenso system (z = 2.68, p < 0.01). Conclusions Both monitoring systems showed acceptable usability and feasibility. There were differences in patient-based evaluations of the two monitoring systems related to the country of the study. Studies investigating the usability and feasibility during longer follow-up periods could perhaps reveal different findings. Future randomized controlled trials investigating the possible positive and negative effects of smartphone-based monitoring systems are needed
The effect of the first manic episode in affective disorder: a case register study of hospitalised episodes
No full textGender differences in patients presenting with a single depressive episode according to ICD-10
No full textDoes Cognitive Dysfunction in Bipolar Disorder Qualify as a Diagnostic Intermediate Phenotype?—A Perspective Paper
Full text linkThe present perspective paper addresses and discusses whether cognitive dysfunction in bipolar disorder qualifies as a diagnostic intermediate phenotype using the Robin and Guze criteria of diagnostic validity. The paper reviews current data within (1) delineation of the clinical intermediate phenotype, (2) associations of the intermediate phenotype with para-clinical data such as brain imaging and blood-based data, (3) associations to family history / genetics, (4) characteristics during long-term follow-up, and (5) treatment effects on cognition. In this way, the paper identifies knowledge gaps and suggests recommendations for future research within each of the five areas. Based on the current state of knowledge, we conclude that cognitive dysfunction does not qualify as a diagnostic intermediate phenotype or endophenotype for bipolar disorder, although promising new evidence points to emotion and reward processing abnormalities as possible putative endophenotypes
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