1,721,253 research outputs found
Editorial to Special Issue “Cognitive Involvement in Multiple Sclerosis”
No full textMultiple sclerosis (MS) is a multifaceted and complex disorder that mainly affects young adults, impacting their work and social abilities [...
What should we expect from multiple sclerosis therapy? Results of an integrated analysis of delayed-release dimethyl fumarate pivotal trials
No full textAsymptomatic bradycardia after first fingolimod dose in a pediatric patient with multiple sclerosis - a case report
No full textFingolimod is currently approved by the US Food and Drug Administration and the European Medicines Agency for the treatment of pediatric patients with relapsing-remitting multiple sclerosis (RRMS). However, transient asymptomatic bradycardia with treatment initiation has been reported in a small population of predisposed patients, which may be a result of short-term activation and internalization/desensitization of the G-protein-gated potassium channel IKACh on the atrial myocyte membrane. Asymptomatic bradycardia, with or without atrioventricular block, is generally self-limiting and has been reported within the first 6 h of administration of the first oral dose of fingolimod. Therefore, patients initiating fingolimod treatment are monitored for this initial period to identify any changes in their electrocardiogram and heart rate that may require further treatment. Here, we report a case of a 17-year-old female with RRMS who received her first fingolimod dose and showed asymptomatic bradycardia that resolved without treatment
Comparative efficacy of fingolimod vs natalizumab: A French multicenter observational study
No full textLa sclerosi multipla in età pediatrica ed adolescenziale
No full textIl volume raccoglie i contributi di docenti universitari, di responsabili di Centri Clinici, di professionisti in campo sanitario e di esperti di bioetica che descrivono secondo un approccio bio-psico-sociale e in un’ottica interdisciplinare la presa in carico di giovani pazienti in età pediatrica e adolescenziale affetti da Sclerosi Multipla e dei loro familiari, approfondendo vari aspetti connessi alla comunicazione della diagnosi e alla gestione e cura di tale patologia cronica neurologica.
Contributi di:
Vincenzo Brescia Morra, Alessandro Chiodi, Domenico Del Forno,
Alessandro Filla, Maria Francesca Freda, Maria Giuliano, Roberta Lanzillo,
Valeria Magri, Stefano Manzo, Anna Napolitano, Marianna Ottobre,
Kyrie Piscopo, Laura Rosa, Antonia Ruggiero, Gioacchino Tedeschi,
Paolo Valerio
Can the use of telemedicine facilitate online prescribing for multiple sclerosis treatment?
No full textTransient muteness followed by dysarthria in patients with pontomesencephalic stroke. Report of two cases.
No full text. Efficacy, safety and tolerability of atorvatstatin in patients with relapsing-remitting multiple sclerosis in treatment with interferonbeta (ARIANNA): a mutlicentre, randomised, double-blind, placebo-controlled, parallel-group-study.
No full textLanzillo R, Moccia M, Laplaud DA, Foucher Y. Comparative efficacy of fingolimod vs natalizumab: A French multicenter observational study. Neurology. 2016 Sep 6;87(10):1066. doi: 10.1212/01.wnl.0000497026.62085.8d. PubMed PMID: 27597557.
No full textOptical coherence tomography angiography detects retinal vascular alterations in different phases of multiple sclerosis
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