168 research outputs found
Theological Reflections on the Blessed Virgin\u27s Impeccabilitas
No full textAbout the author: Father Eamon Carroll, O. Carm., of the School of Sacred Theology of the Catholic University of America, is a past President of the Mariological Society of America
SimJEB: Simulated Jet Engine Bracket Dataset (for review only)
No full textThe Simulated Jet Engine Bracket Dataset (SimJEB) is a collection of finite element models of crowdsourced engine bracket designs. The designs originate from the "GE Jet Engine Bracket Challenge" hosted by GrabCAD.com in 2013. Each entry has a corresponding CAD file, tetrahedral mesh, triangular surface mesh, and structural simulation results from four load cases. The SimJEB dataset is open to the public and licensed under the Open Data Commons Attribution License
project-aero/transient-indicators: Files associated with 2020-01-13 manuscript draft. Author correction.
No full textThe author of the Wolfram Notebook has been corrected to be S. M. O'Regan
Retraction IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2
No full textVolume 424 (2009), pp. 109–118This paper is being retracted at the request of the authors. Three members of the laboratory of the last-named author have tried subsequently to reproduce the result reported in Figure 2B of the paper, but have been unable to do so. Consequently, the authors no longer consider the conclusion that interleukin-1 is able to activate the full-length catalytic subunit of the protein kinase Tpl2 when it is co-transfected into IRAK1-null HEK293 cells that stably express the interleukin-1 receptor to be correct. All of the authors, apart from the first author, have agreed to this retraction.Margaret J. Stafford, Eamon McManus, Dionissios Baltzis, Mark Peggie, Philip Cohen (MRC Protein Phosphorylation Unit, College of Life Sciences, University of Dundee, UK
Change in chronic disease prevalance and health behaviours over the first four waves of TILDA
No full textIs low iron status a risk factor for neural tube defects?
No full textBackground: Folic acid supplements can protect against neural tube defects (NTDs). Low folate and low vitamin B12 status may be maternal risk factors for having an NTD affected pregnancy. However, not all NTDs are preventable by having an adequate folate/ B12 status and other potentially modifiable factors may be involved. Folate and vitamin B12 status have important links to iron metabolism. Animal studies support an association between poor iron status and NTDs but human data are scarce. We examined the relevance of low iron status in a nested NTD case-control study of women within a pregnant population-based cohort.
Methods: Pregnant women were recruited between 1986 and 1990, when vitamin or iron supplementation in early pregnancy was rare. Blood samples, taken at an average of 14 weeks gestation, were used to measure ferritin and hemoglobin in 64 women during an NTD affected pregnancy and 207 women with unaffected pregnancies.
Results: No significant differences in maternal ferritin or hemoglobin concentrations were observed between NTD affected and non-affected pregnancies (case median ferritin 16.8?g/L and hemoglobin 12.4g/dL versus 15.4?g/L and 12.3g/dL in controls). As reported previously, red cell folate and vitamin B12 concentrations were significantly lower in cases. Furthermore, there was no significant association of iron status with type of NTD lesion (anencephaly or spina bifida)
Conclusions: We conclude that low maternal iron status during early pregnancy is not an independent risk factor for NTDs. Adding iron to folic acid for periconceptional use may improve iron status but is not likely to prevent NTDs
25-Hydroxyvitamin D Measurement in Human Hair: Results from a Proof-of-Concept study
No full textVitamin D deficiency has been implicated in numerous human diseases leading to an increased interest in assessing vitamin D status. Consequentially, the number of requests for vitamin D measurement keeps dramatically increasing year-on-year. Currently, the recognised best marker of vitamin D status is the concentration of the 25-hydroxyvitamin D (25(OH)D3) in the blood circulation. While providing an accurate estimate of vitamin D status at the point in time of sampling, it cannot account for the high variability of 25(OH)D3 concentration. In this proof of concept study we set out to provide evidence that 25(OH)D3 can be extracted from hair samples in a similar fashion to steroid hormones. Two of the authors (L.Z. and M.H.) provided hair samples harvested from the crown area of the scalp and the third author (E.L.) provided beard samples. These samples, cut into 1 cm lengths, were weighed, washed and dried. 25(OH)D was extracted using a previously published steroid hormones extraction procedure. Blood samples were taken from the subjects at the same time all tissue samples were analysed using liquid-chromatography mass spectrometry. Hair samples showed presence of quantifiable 25(OH)D3 with concentrations ranging from 11.9–911 pg/mg. The beard sample had a concentration of 231 pg/mg. Serum levels of 25(OH)D3 ranged from 72–78 nmol/L. The results presented here confirm the feasibility of measuring 25(OH)D3 in hair samples. The findings warrant further validation and development and have the potential to yield valuable information relating to temporal trends in vitamin D physiology
Valerolactones and healthy Ageing: Linking Dietary factors, nutrient biomarkers, metabolic status and inflammation with cognition in older adults – The VALID Project
No full textWhat Stand-Up Comedians Teach Us About Library Instruction
No full textIn the article, the author discusses the various lessons that could be learned from a performance of a stand-up comedian which can be used for library instruction. The four lessons include knowing how to read an audience, diversifying one\u27s teaching methods, and relating on a personal level. It features the works of comedian and entertainer Joan Rivers as example
The War Against Public Forgetfulness: Commemorating 1812 in Canada
No full textIn October 2011, the Government of Canada began a two-year, nation-wide celebration of the bicentenary of the War of 1812. The widely-criticized initiative returned the public eye to a traditional 'interpretive tableau' of war heroes, namely Isaac Brock, Tecumseh, Charles de Salaberry and Laura Secord. While the scope and expense of the federal government˙s efforts have been unprecedented, the political battle to maintain certain memories of the War is one that is not new. A struggle against the forgetfulness of Canadians, and particularly young Canadians, has animated commemorations of the War for almost two centuries. Looking at a selection of past commemorative efforts this essay explores how the inertia of a traditional tableau of heroes has tended to overshadow other narratives and newer interpretations. Yet all is not lost. Using the example of the author˙s exhibition, Faces of 1812, it is suggested that publicly-constructed histories can be employed as a useful departure point for the public historian and provide a foundation from which the public can obtain a broader, more critical perspective on both the commemorated events and history writ large
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