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Insomnia and mortality: A meta-analysis
. This manuscript version is made
available under the CC-BY-NC-ND 4.0 license:
http://creativecommons.org/licenses/by-nc-nd/4.0/ which permits use, distribution and reproduction in any medium, provided the original work is properly cited. This author accepted manuscript is made available following 12 month embargo from date of publication (November 2018) in accordance with the publisher’s archiving policyThe purpose of this review was to evaluate the strength of evidence for a relationship between risk of mortality and frequent and ongoing insomnia using a meta-analytic strategy.
Seventeen studies, including a total of 36,938,981 individuals followed up for a mean of 11.6 y, reporting the investigation of the association between mortality and frequent (≥3 nights/wk), ongoing (≥1 mo) insomnia were identified.
There was no difference in the odds of mortality for those individuals with symptoms of insomnia when compared to those without symptoms (OR = 1.06, 95%CI = 0.61–1.84, p = .84). This finding was echoed in the assessment of the rate of mortality in those with and without symptoms of insomnia using the outcomes of multivariate models, with the most complete adjustment for potential confounders, as reported by the individual studies included in this meta-analysis (HR = 1.07, 95%CI = .96–.1.19, p = .22). Additional analyses revealed a tendency for an increased risk of mortality associated with hypnotic use.
The current evidence reinforces the use of cognitive therapy, within a CBTi framework, as a frontline non-pharmacological treatment for insomnia to reassure patients their longevity will not be impacted as a consequence of suffering from insomnia
Daily exercise can shift the endogenous circadian phase.
Body temperature is elevated during and for a short time following strenuous exercise. The
general question of interest is whether habitual exercise can have an entraining effect on the circadian rhythm of body temperature and other rhythms of the circadian system. It is important to evaluate the relative strengths of potential circadian zeitgebers for their possible use in treating the effects of shift work, jet lag and delayed sleep phase syndrome. Bright light appears to be an effective zeitgeber. (1,2) Can physical exercise be one as well
A brief afternoon nap following nocturnal sleep restriction: which nap duration is most recuperative
Relationships between the circadian rhythms of finger temperature, core temperature, sleep latency, and subjective sleepiness
1 OLIVERS YARD, 55 CITY ROAD, LONDON,
ENGLAND, EC1Y 1S
The effect of different wavelengths of light in changing the phase of the melatonin circadian rhythm
Texas, US
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