1,721,026 research outputs found
Reflectance confocal microscopy in infectious diseases
No full textIn vivo reflectance confocal microscope (RCM) is a high-resolution non-invasive imaging technique that was initially focused on the diagnosis of skin cancers. A rising number of other indications have been later described for the diagnosis and management of inflammatory and infectious dermatological disorders. RCM can identify cutaneous parasites that are not visible to naked eye such as Sarcoptes scabiei and Demodex folliculorum and it allows to better identify the different body parts of bigger parasites such as ticks. Fungal filaments can also be identified as elongated bright structures in the cutaneous upper layers. RCM cannot observe virus directly. However, the cytopathic effect associated with some virus can be recognized. In addition of being helpful for the diagnosis and follow-up after treatment, thanks to its non-invasiveness, RCM allows pathophysiological studies
Reflectance confocal microscopy for cutaneous infections and infestations
No full textReflectance confocal microscopy (RCM) is a high-resolution emerging imaging technique that allows non-invasive diagnosis of several cutaneous disorders. A systematic review of the literature on the use of RCM for the study of infections and infestations has been performed to evaluate the current use of this technique and its possible future applications in this field. RCM is particularly suitable for the identification of Sarcoptes scabies, Demodex folliculorum, Ixodes, Dermatophytes and Candida species in the clinical practice and for the follow-up after treatment. The cytopathic effect of herpes simplex virus, varicella zoster virus and molluscipoxvirus is also detectable by this imaging technique even in a pre-vesicular stage. In addition, thanks to its non-invasiveness, RCM allows pathophysiological studies
Diagnosis of scabies by high-magnification dermoscopy: the "delta-wing jet" appearance of Sarcoptes scabiei
No full textConfocal Microscopy for Special Sites and Special Uses
No full textThis article describes the use of confocal microscopy for special sites and unconventional applications. These new applications have been made possible thanks to the introduction on the market of a hand-held camera. Special sites discussed include mucosa, nails, and palms and soles. Special uses discussed include infections and infestations; tumor mapping; understanding clinical, dermoscopic, and histology features; videos and ex vivo confocal microscopy
The contribution of reflectance confocal microscopy in the diagnosis of Paget's disease of the breast
No full textOn the feasibility of confocal microscopy for the diagnosis of scabies [Microscopie confocale pour le diagnostic de la gale : questions sur la faisabilité]
No full textThe role of reflectance confocal microscopy and of optical coherence tomography in the diagnosis of pemphigus
No full textRole of dermoscopy and reflectance confocal microscopy as an aid in the diagnosis of exogenous ochronosis
No full textLaser photodynamic treatment for in situ squamous cell carcinoma of the glans monitored by reflectance confocal microscopy
No full textWhile mutilating surgery can be avoided with non-surgical treatment of in situ squamous cell carcinoma (SCC) of the penis, such as photodynamic therapy (PDT), this procedure is not followed by histological evaluation to verify the total removal of the lesion, leading to possible recurrence. We present the first case of in situ penile SCC treated with laser PDT, where the efficacy of the treatment was monitored by reflectance confocal microscopy (RCM) using a handheld camera. In the future RCM may be regarded as a complementary technique to assess the efficacy of non-surgical treatment of mucous membrane cancers
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