996 research outputs found

    B.S. Johnson and Maureen Duffy: Aspiring Writers: A Conversation with Maureen Duffy

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    Maureen Duffy and B.S. Johnson met at King’s College London in 1956 when they both enrolled to read for a degree in English Literature. They became friends and colleagues through their contributions to Lucifer, the college literary magazine and the wider University of London poetry scene. They later joined forces in the Writer’s Action Group and campaigned for public lending rights for authors. Maureen kindly agreed to be interviewed about her relationship with Johnson, but in addition to this her interview sheds light on the socio-political context of British post-war writing. Maureen was born in 1933 in Worthing, Sussex and came to prominence in 1962 with the autobiographical novel That’s How It Was. Although mainly known for her poetry, her prose work has received critical and popular acclaim. Gor Saga (1981) was dramatised and broadcast by the BBC in 1988 as First Born, a three-part mini-series vehicle for Charles Dance. She is also the author of 16 plays for stage, television and radio. Maureen is well known as a humanist and gay rights activist and for her work championing the financial and legal interests of writers. She is currently the President of the Authors Licensing and Copyright Society, and a Fellow and Vice President of the Royal Society of Literature. This interview took place in London in July 2013 and first appeared in the inaugural edition of B.S.J: The B. S. Johnson Journal

    Introduction

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    In the last four decades, southeastern archaeology has increasingly developed a processual method of looking at archaeological data through varying levels of scale. By adjusting the scale, archaeologists can further define societal interactions and exchanges, which is particularly useful to those researching the Mississippian period, as the rise and fall of chiefdoms was both internally complex and externally influenced by broader regional factors. This use of the most current research methods has enabled a more comprehensive understanding of prehistoric and historic sociopolitical entities. In Archaeological Perspectives of the Southern Appalachians, Ramie A. Gougeon and Maureen S. Meyers have brought together a dozen archaeologists to delineate multiscalar approaches to Native American sites throughout southern Appalachia. The essays range in topic from ceramic assemblages in northern Georgia to public architecture in North Carolina to the frontiers of southern Appalachia in Virginia. Throughout the volume, the contributors discuss varying scales of analysis in their own research to flesh out the importance of maintaining different perspectives when evaluating archaeological evidence. Additionally, the volume makes particular reference to the work of David Hally, whose influence on not only the editors and contributors but on southeastern archaeology as a whole cannot be overstated. While Hally was neither a pioneer nor vocal champion of scale variation, his impeccable research, culminating with the publication of his magnum opus King: The Social Archaeology of a Late Mississippian Town in Northwestern Georgia paved the way for younger scholars to truly develop research methods for holistic social archaeology. Ramie A. Gougeon is an assistant professor with the Division of Anthropology and Archaeology at the University of West Florida. He has contributed chapters to Architectural Variability in the Southeast and Ancient Households of the Americas . Maureen S. Meyers is an assistant professor in the Department of Sociology and Anthropology at the University of Mississippi. Her articles have appeared in Southeastern Archaeology, Native South, and the anthology Mapping the Mississippian Shatter Zone.publishedIntroductio

    Data protection: the challenges facing social networking

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    The popularity of social networking sites has increased dramatically over the past decade. A recent report indicated that thirty-eight percent of online users have a social networking profile. Many of these social networking site users (SNS users) post or provide personal information over the internet every day. According to the latest OfCom study, the average adult SNS user has profiles on 1.6 sites and most check their profiles at least once every other day. However, the recent rise in social networking activity has opened the door to the misuse and abuse of personal information through identity theft, cyber stalking, and undesirable screenings by prospective employers. Behavioral advertising programs have also misused personal information available on social networking sites. Society is now facing an important question: what level of privacy should be expected and required within the social networking environment

    Introduction to Hospitality & Tourism

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    An OER text for created to support Hospitality and Tourism courses at Dutchess Community College. Written, compiled, and designed by Maureen Peters Gittelman.NASUNY DutchessBusiness, Aviation & Construction ProfessionsN/

    Open Access: What is the Climate for OA Publishing and Institutional Repositories in Ohio in 2016?

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    Presentation by Maureen Schlangen of the University of Dayton makes a case for a survey of faculty at Ohio institutions to gauge openness to Open Access archiving and publishing. Those interested in conducting the survey on their campuses are invited to contact the author using the email provided

    "This is why I am different from the others": the abject child as symbol of cultural anxiety

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    This thesis examines Tom Riddle of the Harry Potter novels by J.K. Rowling (1997-2007), Joe Christmas of Light in August by William Faulkner (1932), and Charlie Gordon of Flowers for Algernon by Daniel Keyes (1966) in the context of Julia Kristeva’s theory of the abject. The abject is that which challenges the border between the self, or the state, and that which is outside of it. As such, encounters with the abject trigger reactions of fear, horror, anxiety, or disgust. I argue that these characters—whose identities defy categorization because they are between wizard and Muggle, black and white, and genius and moron—are abject, and thus elicit terror in those who encounter them. Their abjection precludes them from belonging to any sort of community. Moreover, each text highlights its character’s ambiguous, abject identity by associating him with the filth that threatens the body, i.e. blood, vomit, feces, etc. This juxtaposition shows how the characters, as the filth of their societies, are cast out in the name of protecting the clean and proper state. In an increasingly global society, in which borders are porous and rights are expanding, I argue that this refusal to challenge or minimize the border between the self/state and that which is outside of it increases both the self and the state’s vulnerability. By perpetuating ideals of acceptable identities, we create the abject and subject ourselves to feelings terror and anxiety when the clean and proper body, or the clean and proper state, is undoubtedly threatened. I suggest that the abject—and the resulting terror—cannot be overcome unless we challenge the binary system that currently creates communities. We must not try to use discipline or exclusion to regulate or protect from difference. Instead, we must confront our fear and expand the definition of “normal” to include multiple kinds of identities, and diminish anxiety and vulnerability by embracing the reality of the porous border.M.A.Includes bibliographical referencesby Maureen Elizabeth Sarac

    Non-coding RNAs in tumor progression and resistance

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    Les ARN non codants, tels que les miARNs et les lncARNs, sont des régulateurs de l’expression des gènes et peuvent participer à la communication intercellulaire en étant encapsulés dans des petites vésicules extracellulaires. Cependant, leur chargement dans ces vésicules circulantes ainsi que leur rôle dans l’échappement immunitaire et la résistance à la radiothérapie, restent peu connus. Nos travaux montrent que les vésicules extracellulaires de mélanome sont internalisées par des lymphocytes T CD8+ et que leur contenu en miARNs diminue leurs capacités cytotoxiques participant ainsi à l’immunosuppression. Nous avons aussi montré que les cellules de mélanome mutées TP53 sécrètent des vésicules extracellulaires avec un contenu spécifique en miARNs et en lncARNs. Nos résultats suggèrent aussi que la protéine Sam68, dont l’expression est associée aux mutations TP53, contrôle l’expression et l’export de ces ARN non codants dans ces vésicules extracellulaires. Enfin, dans le cancer de la prostate, nous avons montré que l’expression des miARNs est dérégulée dans les cellules tumorales et dans leurs vésicules extracellulaires lors de l’acquisition de la radiorésistance. L’expression du miR-200c-3p est notamment drastiquement diminuée, et sa réexpression resensibilise les cellules radiorésistantes à l’irradiation. En conclusion, ces travaux soulignent le rôle crucial des ARN non codants dans la progression tumorale, l’échappement immunitaire et la résistance à la radiothérapie. Ces résultats pourraient conduire au développement de nouvelles thérapies et/ou de nouveaux biomarqueurs circulants pronostic de la réponse au traitement.Non-coding RNAs, such as miRNAs and lncRNAs, are important regulators of gene expression and can participate in intercellular communication by being encapsulated in small extracellular vesicles. However, little is known about their loading into these vesicles neither in their role in immune escape and resistance to radiotherapy. We found that melanoma extracellular vesicles are internalized by CD8+ T cells, and that their miRNA content reduces their cytotoxic activity to participate in immune suppression. Furthermore, we showed that TP53-mutant melanoma cells secrete extracellular vesicles with a specific miRNA and lncRNA cargo. Our results also suggest that the Sam68 protein, whose expression is associated with TP53mutations, controls the expression and the loading of these non-coding RNAs in melanoma extracellular vesicles. Finally, we showed that miRNA expression is deregulated in prostate cancer cells and their extracellular vesicles during radioresistance acquisition. In particular, miR-200c-3p expression is highly decreased, and its reexpression resensitizes radioresistant cells to irradiation. Altogether, this work highlights the critical role of non-coding RNAs in tumor progression, immune escape and resistance to radiotherapy. These results could lead to the development of new therapies and prognostic biomarkers

    Disseminating Cochrane evidence to the public health workforce via author-led webinars

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    <b>Title</b>\ud \ud - Disseminating Cochrane evidence to the public health workforce via author-led webinars\ud \ud <b>Background</b> \ud \ud - <u><a href="http://www.healthevidence.org/">Health Evidence™</a></u> is a free searchable repository, of 4,500+ quality-appraised public health relevant reviews, including nearly 700 Cochrane reviews. Author-led webinars is one knowledge translation strategy to disseminate the findings of Cochrane reviews.\ud \ud <b>Objectives</b>\ud \ud - (i) Disseminate the findings of Cochrane reviews via webinars\ud \ud - (ii) Evaluate the impact of Cochrane author-led webinars \ud \ud <b>Methods</b>\ud \ud - Webinars are 60-90 minutes in length and include: an overview of the principles of evidence-informed decision making (15mins), a presentation of the findings by the review author (30mins), and a Q&A period (30mins). Webconferencing software monitors participant registration, attendance, engagement, poll responses, and questions. Standard polling questions are asked throughout each session to assess familiarity with and use of systematic reviews, as well as familiarity and agreement with session-specific review findings.\ud \ud <b>Results</b>\ud \ud - Since January 2015 Health Evidence™ has hosted six Cochrane author-led webinars. Webinar participants include: nurses, health promoters, physicians, dietitians, and knowledge brokers. On average, participants in each session were attentive and engaged 68.8% of the time. Google Analytics reflect an average 572% increase in users accessing the Cochrane review featured in each webinar on the day of the session compared to average daily access the month prior. On average, each session attracted 177 registrants, of which approximately half joined on the session date. Poll response data reveal 59.6% attendees use systematic reviews to inform their practice. Data collected pre/post on participant’s knowledge of the effectiveness of an intervention, suggest that webinars are an effective way to influence participant’s knowledge about intervention effectiveness (participant knowledge improved 10-31.8%, measured via pre/post poll questions). During the Q&A period, attendees submitted 5-12 questions per session.\ud Conclusion: Webinars are an interactive and effective mechanism for promoting public health relevant Cochrane evidence to decision makers. Data from webinars highlight a high level of interest and engagement with Cochrane author-led sessions

    Growing occupation of professional writing in academic spaces: Combinations of theory and practice

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    The book chapter, "Growing occupation of professional writing in academic spaces: combinations of theory and practice" is written by the listed authors including Maureen Nicholson (Douglas College).Writing Centres, Writing Seminars, Writing Culture: Writing Instruction in Anglo-Canadian Universities brings together insights into the history of how writing has been taught in Canadian universities alongside profiles of how specific university academic units teach writing today. Engineering courses, writing centers, and writing programs are all represented, each one providing different models of how writing can be taught within their specific academic context. The editors' introduction, an essay surveying current practices throughout Canadian universities, and the Afterword by Russ Hunt suggest ways of making sense of the tangled garden that is the teaching of writing in Canadian universities. --From publisher description

    A Motivational Interviewing Curriculum for Occupational Therapists in Physical Disabilities Settings to Integrate Self-Management Into Their Practice

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    Abstract Date Presented 4/1/2017 Motivational interviewing is a useful tool to promote partnership skills in occupational therapy practice. This presentation introduces a motivational interviewing curriculum for occupational therapy practitioners working in physical disability settings and describes results of the evaluation. Primary Author and Speaker: Maureen Gecht-Silver Additional Authors and Speakers: Elizabeth Peterson, Joy Hammel</jats:p
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