113,082 research outputs found

    Vitamin-V: Virtual Environment and Tool-boxing for Trustworthy Development of RISC-V based Cloud Services

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    Vitamin-V is a 2023-2025 Horizon Europe project that aims to develop a complete RISC-V open-source software stack for cloud services with comparable performance to the cloud-dominant x86 counterpart and a powerful virtual execution environment for software development, validation, verification, and test that considers the relevant RISC-V ISA extensions for cloud deployment

    Osteoarthritis of the temporomandibular joint in an adult patient with Hashimoto thyroiditis: case report.

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    This case report documents the treatment of a female patient, 37 years 6 months of age, with a Class II open bite malocclusion with severe osteoarthritis of the temporomandibular joint associated with Hashimoto disease, a chronic inflammatory disease of the thyroid in which autoimmune factors play a prominent role. The simultaneous treatment of both pathologies (malocclusion and thyroiditis) led to the cessation of pain and dysfunctional symptoms in both temporomandibular joints

    Hydroperoxides and cytokines as biomarkers in detecting atherosclerosis predisposition in cigarette smokers

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    Objectives: Smoking increases oxidative modi-fication of LDL, associated with lower HDL plasma levels, systemic inflammatory response and endothelial dysfunction. We tested the hy-pothesis that the risk status for coronary atherosclerosis disease (CAD) of cigarettes smokers might be identified by means of serum oxidative levels and vascular inflammation de-termination. Design and Methods: Oxidative stress levels, cytokines, and the metabolic status were investigated on 499 subjects admit-ted to our institute. The association between biomarkers and smoking habits in the pres-ence/absence of disease and with the number of vessel affected, was studied. Results: Oxidative stress and inflammatory levels (p < 0.001) were strongly induced by smoking habits. Serum values of the subjects categorised as CAD, non CAD and healthy subjects differed significantly (p < 0.001) only for the degree of oxidative stress. Glycaemia was able to affect C-reactive protein serum levels with a positive association (p < 0.05). The analysis of the study population in-dicated that serum oxidative stress levels sig-nificantly increased with increasing number of vessels affected (p < 0.01). When statistical analysis was performed separately in both smoking groups, smokers did not show any particular difference for both oxidative stress and inflammation markers between the two groups of cardiovascular patients (CAD and non CAD) and the control group, while for non smokers, the differences were evident. Conclu-sion: These findings indicate that the consid-ered biomarkers, especially oxidative stress, can be useful to predict the biological damage caused by cigarette smoking, as well as to iden-tify subjects characterised by a higher risk of cardiovascular event, but cannot evaluate the presence of disease in subjects with smoking habit

    author-bios-SRD-19-0063.R1 – Supplemental material for The Network Structure of Police Misconduct

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    Supplemental material, author-bios-SRD-19-0063.R1 for The Network Structure of Police Misconduct by George Wood, Daria Roithmayr and Andrew V. Papachristos in Socius</p

    Hunting behavior of Late Neanderthals in the North-east of Italy. Results from zooarchaeological analysis of unit II assemblage of Grotta Maggiore di San Bernardino (Berici Hills, Vicenza).

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    Grotta Maggiore di San Bernardino is located in the Berici Hills, in northeastern Italy, at about 135 m above sea level. The cavity was subject of systematic excavations carried out by the University of Ferrara in 1959-1964 and between 1986-1993. Field investigations explored a stratigraphic series of about 4 m thickness, which includes 8 main units dating from MIS 7 to MIS 3. The focus of this work is the zooarchaelogical analysis of Unit II (MIS3). It records an intense human occupation attested by hearths, temperate type associated faunal remains and Mousterian lithic implements. Bone assemblage shows a prevalence of medium and large sized ungulates: the most frequent species are roe deer, red deer, wild boar, moose and giant deer, followed by bovids and caprids. Carnivores are less numerous, represented by different species and the cave bear is the most represented. Were recovered also rhinoceros and beaver remains. The presence of Castor fiber together with waterfowl (duck, geese) and fishes indicates the existence of humid environments and watercourses in the surroundings. Bone taphonomy has identified high incidence of burned remains and of anthropic actions ascribable to different stages of the butchering process like skinning, dismembering and filleting. Several fragmentary bone shafts show typical stigmata due to their use as retouchers for flint tools. As Faunal assemblages similar to Grotta San Bernardino unit II can be observed in the Mousterian levels of other sites of the Berici Hills (Grotta di Paina, Grotta del Col della Stria, Grotta de Nadale) and Lessini Mountains (Grotta di Fumane, Riparo Tagliente). Grotta di San Bernardino represents a further case of Neanderthal behavior in terms of subsistence. Additional faunal analyses, will cast new light on the site and clarify its relationship with the territory, the organization of the site itself, the activities, the hunting areas and the chronology of the occupation
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