848 research outputs found

    SULFUR DIOXIDE-INDUCED BRONCHOCONSTRICTION VIA RUTHENIUM RED-SENSITIVE ACTIVATION OF SENSORY NERVES

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    The mechanism of sulfur dioxide-induced bronchoconstriction was studied using isolated perfused and ventilated guinea-pig lungs. They were exposed to sulfur dioxide after pretreatment with different compounds, either via the pulmonary artery or via the air passages. Neither the cyclooxygenase inhibitor indomethacin (30 muM) nor the H-1-receptor antagonist diphenhydramine (15 muM), given via the perfusate, attenuated the sulfur dioxide-induced bronchoconstriction. Furthermore, sulfur dioxide exposure did not cause a release of either thromboxane or histamine into the perfusate. In experiments with atropine equivocal results were obtained with regard to protection against sulfur dioxide-evoked bronchoconstriction. Intratracheal instillation of the local anesthetic agent lidocaine (1 mg/50 mul) markedly reduced the sulfur dioxide-induced bronchoconstriction. Also, ruthenium red (10 muM), an agent with calcium entry-blocking properties and an inhibitor of capsaicin-induced bronchoconstriction, was able to inhibit the effect of sulfur dioxide. The sulfur dioxide-induced bronchoconstriction was associated with release of calcitonine gene-related peptide, a sensory neuropeptide. The effect of sulfur dioxide was also inhibited by a Ca2+-free buffer plus EGTA. These results suggest that sulfur dioxide-induced bronchoconstriction in the guinea-pig lung is the result of a local effect on sensory nerves (C-fiber activation). The mechanism seems to be dependent on the Ca2+-dependent release of sensory neuropeptides and to be linked to opening of the cation channel, which is associated with the proposed capsaicin receptor on sensory nerves as revealed by the inhibitory effect of ruthenium red

    IMPLEMENTASI LAYANAN INFORMASI KARIR UNTUK MEMBANTU KESIAPAN PESERTA DIDIK DALAM PEMILIHAN KARIR DI SMA YP UNILA BANDAR LAMPUNG

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    ABSTRAK Peneliti memperoleh gambaran bahwa peserta didik Di SMA YP UNILA Bandar Lampung masih ada beberapa siswa yang masih bingung tentang sekolah lanjutan setelah dari SMA dan juga menentukan arah hidupnya atas apakah ingin melanjutkan pendidikan ke perguruan tinggi atau bekerja. Berdasarkan hal tersebut penulis tertarik untuk djudul “Implementasi Layanan Informasi Karir Untuk Membantu Kesiapan Peserta Didik Dalam Pemilihan Karir di SMA YP UNILA Bandar Lampung”. Adapun Tujuan dari penelitian ini pertama, untuk mengetahui dan manganalisis bagaimana Implementasi layanan informasi karir untuk membantu kesiapan peserta didik dalam pemilihan karir di SMA YP UNILA Bandar Lampung. Kedua, Untuk mengetahui dan manganalisis apa saja hambatan-hambatan yang ada dalam implementasi layanan informasi karir untuk membantu kesiapan peserta didik dalam pemilihan karir di SMA YP UNILA Bandar Lampung. Ketiga, Untuk mengetahui dan manganalisis seperti apa hasil daripada implememtasi layanan informasi karir untuk membantu kesiapan peserta didik dalam pemilihan karir di SMA YP UNILA Bandar Lampung. Metode Penelitian adalah pendekatan kualitatif, penelitian ini termasuk kedalam jenis penelitian lapangan (field research). Penelitian ini menggunakan teknik pengumpulan data berupa wawancara, observasi dan dokumentasi. Data primer sumber data yang didapat melalui wawancara dengan guru bimbingan dan konseling. Data sekunder didapat melalui media perantara yang dapat berupa dokuementasi dari responden yaitu guru bimbingan dan konseling di SMA YP UNILA Bandar Lampung. Penelitian ini dilaksanakan mulai dari perencanaan yang berupa penyusunan RPL (Rancangan Perencanaan Layanan). Kemudian dalam pelaksanaanya pertama, kegiatan pendahuluan. Kedua, kegiatan inti dan ketiga, kegitan penutup. Kemudian setelah selesai pelaksanaanya dilanjut dengan tahap akhir yakni tahap evaluasi. Pada tahap evaluasi dalam implementasi layanan informasi tentang karir untuk membantu kesiapan peserta didik dalam pemilihan karir di SMA YP UNILA Bandar Lampung dilakukan melalui dua tahap evaluasi yakni evaluasi proses dan evaluasi hasil. Dimana Kedua jenis evaluasi ini penting dalam memastikan efektivitas dan keberhasilan suatu aktivitas atau proyek. iv Berdasarkan pada hasil penelitian yang dilakukan oleh peneliti seputar Implementasi layanan informasi tentang karir untuk membantu kesiapan peserta didik dalam pemilihan karir di SMA YP UNILA Bandar Lampung tedapat hambatan dalam pelaksanaanya berupa kurang akuratnya informasi yang didapat, kemudian keberagaman karir dari tiapindividu peserta didik. Akan tetapi hasil dari implementasi layanan informasi tentang karir untuk membantu kesiapan peserta didik dalam pemilihan karir di SMA YP UNILA Bandar Lampung yakni tentunya peserta didik dapat memperoleh solusi dari layanan informasi karir terkait pemilihan karir mereka. Kata Kunci : Implementasi, Layanan Informasi Karir, Peserta Didik v ABSTRACT The researcher obtained an illustration that there were still some students at YP UNILA SMA Bandar Lampung who were still confused about going to secondary school after high school and also determining the direction of their life whether they wanted to continue their education to college or work. Based on this, the author is interested in the title "Implementation of Career Information Services to Assist Students' Readiness in Career Choices at SMA YP UNILA Bandar Lampung". The objectives of this research are 1. To find out and analyze how career information services are implemented to help students' readiness in choosing a career at SMA YP UNILA Bandar Lampung. 2. To find out and analyze what obstacles exist in implementing career information services to help students' readiness in choosing a career at SMA YP UNILA Bandar Lampung. 3. To find out and analyze the results of implementing career information services to help students' readiness in choosing a career at SMA YP UNILA Bandar Lampung. The research method is a qualitative approach, this research is included in the type of field research. This research uses data collection techniques in the form of interviews, observation and documentation. Primary data is a source of data obtained through interviews with guidance and counseling teachers regarding the Implementation of Career Information Services to Assist Students' Readiness in Career Choices at YP UNILA SMA Bandar Lampung. Secondary data sources are obtained through intermediary media which can be in the form of documentation from respondents, namely guidance and counseling teachers at SMA YP UNILA Bandar Lampung. This research was carried out starting from planning in the form of preparing an RPL (Service Planning Plan). Then in the first implementation, preliminary activities. Second, core activities and third, closing activities. Then after completion of the implementation, it continues with the final stage, namely the evaluation stage. At the evaluation stage, the implementation of career information services to help students' readiness in choosing a career at SMA YP UNILA Bandar Lampung was carried out through two evaluation stages, namely process evaluation and results evaluation. Where these two types of evaluation are important in ensuring the effectiveness and success of an activity or project. Based on the results of research conducted by researchers regarding the implementation of information services about careers vi to help students' readiness in choosing a career at SMA YP UNILA Bandar Lampung, there are obstacles in its implementation in the form of less accurate information obtained, then the diversity of careers for each individual student. However, the result of implementing information services about careers to help students' readiness in choosing a career at YP UNILA High School Bandar Lampung is that of course students can get solutions from career information services regarding their career choices. Keyword : Implementation, Career Information Services, Student

    Yeast Particle Encapsulation of Scaffolded Terpene Compounds for Controlled Terpene Release

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    Terpenes are naturally occurring compounds produced by plants that are of great commercial interest in the food, agricultural, cosmetic, and pharmaceutical industries due to their broad spectra of antibacterial, antifungal, anthelmintic, membrane permeation enhancement, and antioxidant biological activities. Applications of terpenes are often limited by their volatility and the need for surfactants or alcohols to produce stable, soluble (non-precipitated) products. Yeast particles (YPs) are hollow, porous microspheres that have been used for the encapsulation of terpenes (YP terpenes) by passive diffusion of terpenes through the porous YP cell walls. We here report the development of a second generation YP encapsulated terpene technology that incorporates the stimuli-responsive control of terpene release using biodegradable pro-terpene compounds (YP pro-terpenes). YP terpenes and YP pro-terpenes were both produced, in which high levels of carvacrol, eugenol, thymol and geraniol were encapsulated. The YP pro-terpenes show higher encapsulation stability than YP terpenes due to pro-terpenes being non-volatile solids at room temperature and stable in suspensions at neutral pH. YP pro-terpenes and YP terpenes were evaluated for biological activity in antibacterial, antifungal and anthelmintic assays. The YP pro-terpenes retained the full biological activity of the parent terpene compound

    A note on Condorcet consistency and the median voter

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    We discuss to which extent the median voter theorem extends to the domain of single-peaked preferences on median spaces. After observing that on this domain a Condorcet winner need not exist, we show that if a Condorcet winner does exist, then it coincides with the median alternative ('the median voter'). Based on this result, we propose two non-cooperative games that implement the unique strategy-proof social choice rule on this domain. --

    Doppler effect of gamma-ray bursts in the fireball framework

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    The influence of the Doppler effect in the fireball framework on the spectrum of gamma-ray bursts is investigated. The study shows that the shape of the expected spectrum of an expanding fireball remains almost the same as that of the corresponding rest frame spectrum for constant radiations of the bremsstrahlung, Comptonized, and synchrotron mechanisms as well as for that of the GRB model. The peak flux spectrum and the peak frequency are obviously correlated. When the value of the Lorentz factor becomes 10 times larger, the flux of fireballs would be several orders of magnitude larger. The expansion speed of fireballs is a fundamental factor of the enhancement of the flux of gamma-ray bursts.Astronomy & AstrophysicsSCI(E)EI40ARTICLE2705-71339

    EXPERIMENTAL INVESTIGATION INTO THE DYNAMIC BEHAVIOR OF CIRCULAR RINGS WITH ARC-SHAPED SUPPORTS

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    Results are presented of an experimental study on the dynamic behavior of metallic thin-walled circular rings with are-shaped supports subjected to a symmetrically concentrated impact load.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995QN47100009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Engineering, MultidisciplinaryEngineering, MechanicalSCI(E)EI2ARTICLE183-856

    Effects of R-parity violation on the charged Higgs boson decays

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    We calculate one-loop R-parity-violating coupling corrections to the processes H- -> tau v(tau), and H- -> bt. We find that the corrections to the H- -> tau v(tau) decay mode are generally about 0.1%, and can be negligible. But the corrections to the H- -> bt decay mode can reach a few percent for the favored parameters.Physics, MultidisciplinarySCI(E)中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)0ARTICLE5873-8784

    Similarity consideration of structural bifurcation buckling

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    Many structural bifurcation buckling problems exhibit a scaling or power law property. Dimensional analysis is used to analyze the general scaling property. The concept of a new dimensionless number, the response number-Rn, suggested by the present author for the dynamic plastic response and failure of beams, plates and so on, subjected to large dynamic loading, is generalized in this paper to study the elastic, plastic, dynamic elastic as well as dynamic plastic buckling problems of columns, plates as well as shells. Structural bifurcation buckling can be considered when Rn(n) reaches a critical value

    Quasi-linear viscoelastic properties of fibrotic neck tissues obtained from ultrasound indentation tests in vivo

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    Author name used in this publication: Sing-Fai Leung2004-2005 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishedGreen (AAM
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