12,429 research outputs found
Géographies sociales pour les « zones intérieures ». Des confins qui territorialisent : le cas des Sicani (Sicile)
No full textCes dernières années, en Italie, la Stratégie Nationale pour les zones intérieures (SNAI) a encouragé les politiques de développement des territoires périphériques et ultrapériphériques italiens, définis sur la base de services essentiels en matière de santé, d’éducation et de mobilité. Cet article réfléchit sur la SNAI d’un point de vue strictement géographique : cette politique est présentée à travers quelques concepts clés de la géographie sociale italienne et française. À travers le prisme de la théorie de la territorialisation, nous lisons le SNAI comme un dispositif qui a établi des nouveaux confins et activé des processus de territorialisation. Nous réfléchissons à la fonction principalement dénominative de cette politique qui, en nommant ces territoires « zones intérieures », a produit une véritable géographie de la périphéricité. Dans un deuxième temps, les critères qui ont produit cette géographie sont analysés afin de faire ressortir la visée intentionnelle (Raffestin, 1980) que la Stratégie sous-tend. La réflexion théorique s’appuie sur une étude de cas : la zone de Sicani dans la province d’Agrigente, en Sicile, où est active la Stratégie Terre Sicane. La contribution chevauche un certain nombre de confins : tout d’abord, des confins entre différentes époques, dans la mesure où on utilise une littérature géographique qui est en quelque sorte historique afin d’interpréter une politique et des phénomènes territoriaux actuels. Deuxièmement, la réflexion se déplace le long d’un des confins de la géographie sociale elle-même, principalement dédiée aux questions urbaines. On considérera ces confins comme des lieux poreux : une zone de transit, de franchissement et de perméabilité. Les frontières comme des surfaces non pas linéaires mais zonales
An investigation of the beneficial effects of adding carbon nanotubes to standard injection grout
No full textMortar grouting is often used in masonry constructions to mitigate structural decay and repair damage by filling cracks and voids, resulting in an improvement in mechanical properties. This paper presents an original experimental investigation on grout with added carbon nanotubes (CNTs). The samples were prepared with different percentages of CNTs, up to 1.2 wt% with respect to the binder, and underwent three‐point bending tests in crack mouth opening displacement mode and compressive tests. The results showed that very small additions (up to 0.12 wt% of CNTs) increased not only flexural and compressive strengths (+73% and 35%, respectively, in comparison with plain mortar) but also fracture energy (+80%). These results can be explained on the basis of a reduction in porosity, as evidenced by mercury intrusion porosimetry, as well as by a crack bridging mechanism and by the probable formation of nucleation sites for hydration products, as observed through scanning electron microscopy
Approximating travelling waves by equilibria of non-local equations
No full textWe consider an evolution equation of parabolic type in R having a travelling wave solution. We study the effects on the dynamics of an appropriate change of variables which transforms the equation into a non-local evolution one having a travelling wave solution with zero speed of propagation with exactly the same profile as the original one. This procedure allows us to compute simultaneously the travelling wave profile and its propagation speed avoiding moving meshes, as we illustrate with several numerical examples. We analyze the relation of the new equation with the original one in the entire real line. We also analyze the behavior of the non-local problem in a bounded interval with appropriate boundary conditions. We show that it has a unique stationary solution which approaches the traveling wave as the interval gets larger and larger and that is asymptotically stable for large enough intervals. © 2012 - IOS Press and the authors. All rights reserved
On a nonlocal moving frame approximation of traveling waves
No full textThe profiles of traveling wave solutions of a 1-d reaction-diffusion parabolic equation are transformed into equilibria of a nonlocal equation, by means of an appropriate nonlocal change of variables. In this new formulation both the profile and the propagation speed of the traveling waves emerge as asymptotic limits of solutions of a nonlocal reaction-diffusion problem when time goes to infinity. In this Note we make these results rigorous analyzing the well-posedness and the stability properties of the corresponding nonlocal Cauchy problem. We also analyze its restriction to a finite interval with consistent boundary conditions. For large enough intervals we show that there is an asymptotically stable equilibrium which approximates the profile of the traveling wave in R. This leads to efficient numerical algorithms for computing the traveling wave profile and speed of propagation. © 2011 Académie des sciences
The SSC of the Generalised Jahangir’s Graph Jm,k and its Algebraic Characterizations
No full textIn this article, we present important combinatorial and algebraicproperties of spanning simplicial complex (SSC) of the generalised Jahangir’sgraph Jm,k. We describe the relation to find f−vectors associatedto Δs(Jm,k) and determine the Hilbert series for the SR-ring KΔs(Jm,k).In the end, we present the associated primes of the facet ideal IF(Δs(Jm,k))and the Cohen-Macaulay characterization of the SR-ring of Δs(Jm,k).AMS (MOS) Subject Classification Codes: Primary 13-P10, Secondary 13-F20, 13-C14, 13-H10.Corresponding Author: Agha KashifKey Words: Simplicial Complexes, f-vectors, Spanning Trees, Face Ring, Hilbert Series, CohenMacaulay
To <i>JM</i> on Its 75th Anniversary
No full text This article discusses how Journal of Marketing ( JM) has influenced marketing science and practice by publishing articles on substantive topics relevant to customers, managers, organizations, markets, and society. The journal's 75th anniversary coincides with the 50th anniversary of the Marketing Science Institute (MSI). Frequently, JM and MSI have collaborated to address important substantive marketing issues identified in MSI's Research Priorities. The author highlights seminal articles on brand equity; business-to-business marketing (including sales force management); connecting marketing information, metrics, and strategy; consumer behavior; innovation, new product development. and product management; marketing orientation and capabilities; and market research, methodology and services. She also draws attention to articles that have won the Sheth Foundation/ JM Award and the H. Paul Root Award. The article describes how JM‘s knowledge dissemination is amplified by powerful social network effects. Ideas in JM articles diffuse through the business community, influencing the mind-set of managers worldwide. </jats:p
Recombination Patterns for Natural Syntax
No full textA formalism is introduced for representing general mechanisms of syntax recombination in natural languages
Analysis of the effect of high heel shoes design components on gait ground reaction forces
No full textThis work is part of the activities driven by ADDfactor, Advanced Digital technologies and virtual engineering for mini-factories. This project has receied funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement No. [609386].Baydal Bertomeu, JM.; Lopez Pascual, J.; Puigcerver Palau, SA.; Solves Camallonga, C.; Belda Lois, JM. (2015). Analysis of the effect of high heel shoes design components on gait ground reaction forces. Footwear Science. 7:S129-S131. https://doi.org/10.1080/19424280.2015.1038647SS129S131
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
No full text\ua9 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Studies showed that JM-20, a benzodiazepine-dihydropyridine hybrid molecule, protects against rotenone and 6-hydroxydopamine neurotoxicity. However, its protective effects against cytotoxicity induced by endogenous neurotoxins involved in Parkinson’s disease (PD) pathogenesis have never been investigated. In this study, we evaluated the ability of JM-20 to inhibit alpha-synuclein (aSyn) aggregation. We also evaluated the interactions of JM-20 with aSyn by molecular docking and molecular dynamics and assessed the protective effect of JM-20 against aminochrome cytotoxicity. We demonstrated that JM-20 induced the formation of heterogeneous amyloid fibrils, which were innocuous to primary cultures of mesencephalic cells. Moreover, JM-20 reduced the average size of aSyn positive inclusions in H4 cells transfected with SynT wild-type and synphilin-1-V5, but not in HEK cells transfected with synphilin-1-GFP. In silico studies showed the interaction between JM-20 and the aSyn-binding site. Additionally, we showed that JM-20 protects SH-SY5Y cells against aminochrome cytotoxicity. These results reinforce the potential of JM-20 as a neuroprotective compound for PD and suggest aSyn as a molecular target for JM-20
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