214 research outputs found
The Latest Prevalence, Isolation, and Molecular Characteristics of Feline Herpesvirus Type 1 in Yanji City, China
No full textEpidemiological surveys revealed that 33 of the 93 samples were positive for FHV-1, with the gD gene of these 33 samples exhibiting low variation, high homology, and no critical amino acid mutation. Feline herpesvirus type 1 (FHV-1), also known as feline viral rhinotracheitis (FVR) virus, is one of the main causes of URT disease in cats. All cats can become hosts of FHV-1, and the spread of this disease affects the protection of rare feline animals. Nasal swabs from cats with URT disease were collected at five veterinary clinics in Yanji City from 2022 to 2024. The purpose of this study was to isolate and investigate the epidemiology of FHV-1. The gD gene of the FHV-1 strain was cloned and inserted into the pMD-18T vector and transformed into a competent Escherichia coli strain. Subsequently, the gD gene of the positive samples was sequenced and phylogenetic analysis was performed to determine the genetic evolution relationship between the strains. We successfully isolated the FHV-1 strain YBYJ-1 in Yanji City for the first time. The diameter of the virus is approximately 150–160 nm. After 48 h of virus inoculation, the cells were round, isolated, and formed grape-like clusters. The gD gene of the virus was sequenced, and the length was 1125 bp, which proved the isolate was FHV-1. This study found that the genetic evolution of the FHV-1 gD gene was stable, expanding the molecular epidemiological data on FHV-1 in cats in Yanji City
Eastern extension of the Solonker‐Xar Moron‐Changchun‐Yanji Suture Zone: Constraints from thermochronology of sedimentary and mafic rocks in the Hunchun‐Yanji area, Northeast China
No full textThe Late Palaeozoic Solonker‐Xar Moron‐Changchun‐Yanji Suture (SXCYS) is considered to mark the location of the final closure of the Paleo‐Asian Ocean, which separated the North China Craton to the south and the amalgamated blocks to the north in Northeast China. There has always been controversy about its eastern extension in Northeast China and the final closure time of the Paleo‐Asian Ocean. To explore this issue, we collected gabbro and quartz‐diorite samples in the Hunchun area for the genesis of mafic magma and age dating, and five groups of Permian to Triassic sandstones belonging to both sides of the potential suture locations in the middle and east Jilin Province for the provenance analysis to discuss the final closure time of the Paleo‐Asian Ocean and the possible positions of the eastward termination of the SXCYS. The gabbro reveals a Middle Permian concordia average age of 266.9 ± 5.2 Ma, and the quartz diorite reveals a Late Permian Concordia average age of 258.8 ± 4.8 Ma. Lithological and geochemical analysis reveal the two rock samples belong to low‐K arc tholeiites from the oceanic island and calk‐alkaline volcanics from the active continental margin, respectively, which implies that during the middle to late Permian, the SW margin of the Jiamusi–Khanka Block (JB) continuously experienced the subduction process from the Paleo‐Asian Ocean Plate. The final closure time of the Paleo‐Asian Ocean should be later than the Late Permian. Meanwhile, four groups of sandstone from the east Jilin reveal typically Jiamusi–Mongolia Block (JMB) provenance features, with age components of ~500 Ma, ~0.9–1.5 Ga implying that the Wangqing, Hunchun, Kaishantun area belongs to the northern part of the SXCYS from late Early Permian to Middle Triassic, with youngest age components of 288.2 ± 2.8, 275.5 ± 1.8, 250 ± 1.7, and 244.9 ± 1.7 Ma, respectively. The late Early Permian sandstone from the middle Jilin reveals the youngest age component of 273.8 ± 3.4 Ma and the age component of 487 ± 3 Ma also revealing JMB feature. Comparing to previous studies, we propose that the Paleo‐Asian Ocean finally closed during Middle to Late Triassic. A possible ENE fault separates the eastern extension of SXCYS into two parts, which means the possible position of the eastward extension of the SXCYS should go along the Wangqing‐Kaishantun with NNW direction in the west, Hunchun‐Laoheishan with NW direction in the east.China Scholarship Council https://doi.org/10.13039/501100004543Qingdao National Laboratory for Marine Science and Technology https://doi.org/10.13039/50110001095
Multifunctional Applications of Extracellular Nanovesicles for Acute Kidney Injury and Renal Fibrosis; a Mini Review
No full textRuizhe Xu,1 Shuainan Liu,2 Zhenhua Cui1 1Department of Nephrology, College of Medicine, Yanbian University, Yanji, Jilin, 133000, People’s Republic of China; 2Department of Dermatology, College of Medicine, Yanbian University, Yanji, Jilin, 133000, People’s Republic of ChinaCorrespondence: Zhenhua Cui, Department of Nephrology, College of Medicine, Yanbian University, Yanji, Jilin, 133000, People’s Republic of China, Tel +86 433 273 2352, Email [email protected]: Extracellular vesicles (EVs) are released into body fluids, including blood, urine, saliva, pleural and peritoneal fluid, by various cell types through different mechanisms. Various types of EVs differ in structure and function; but, their common characteristic is carrying a variety of bioactive molecules such as RNA, proteins, and lipids. EVs can regulate the function of target cells through interaction with them. Acute kidney injury (AKI) is a common and potentially serious clinical condition characterized by a rapid decline in renal function, manifested as abnormal classic indicators such as serum creatinine and decreased urine output. AKI not only affects the renal function of patients, but it is also closely related to dysfunction in other organs, including the lung, heart, brain, liver, intestine, and immune system. EVs by carrying bioactive molecules (eg, proteins, RNA, lipids) and mediating intercellular communication can play critical roles in inflammation, apoptosis, tubular injury, and fibrosis during AKI. Some key mechanisms of EVs in AKI pathophysiology include promoting tubular cell proliferation, enriching HMGB1/HSP70, leading to NF-Kβ/MAPK activation, and carrying pro-inflammatory molecules (eg, TNF-α, IL-1β, IL-6). In the context of renal fibrosis, EVs can directly participate in its pathogenesis by carrying pro-fibrotic factors and regulating fibroblast activity, accelerating the progression of fibrosis. Besides being involved in the pathogenesis, EVs can also serve as potential diagnostic tools and therapeutic agents against AKI and renal fibrosis. This narrative review summarizes the biogenesis, composition, and functional mechanisms of EVs in AKI as well as renal fibrosis pathogenesis, along with highlighting their potential as diagnostic biomarkers and therapeutic targets.Keywords: extracellular vesicles, exosomes, acute kidney injury, biomarker
Eastern extension of the Solonker‐Xar Moron‐Changchun‐Yanji Suture Zone: Constraints from thermochronology of sedimentary and mafic rocks in the Hunchun‐Yanji area, Northeast China
No full textMolecular detection of Theileria species in cattle from Jilin Province, China
No full textBovine theileriosis is a tick-borne disease that is hampering the development of
the domestic cattle industry in northern China. This study involved a molecular survey of
bovine Theileria species in 137 blood samples from cattle in the Jilin province of China. The
DNA samples were screened by species-specific 18S rRNA PCR. Results revealed that 19.7%
(27/137), 17.5% (24/137) and 10.9% (15/137) were found to be infected with Theileria sinensis,
Theileria orientalis, respectively. Mixed infection was found in 8.8% (12/137). The overall
detection rates of Baishan, Yanji, Jilin and Liaoyuan districts was 60.0%, 17.5%, 5.3% and 0%,
respectively. There is little information on the detection and distribution of bovine Theileria
species in northern China. Therefore, this study provides important data for understanding
the epidemiology of Theileria species and designing appropriate approaches for the diagnosis
and control of bovine theileriosis in northern China
Development of buoyancy regulating system for underwater glider
No full text[Objectives] Buoyancy regulating system is a key component of an underwater glider for controlling submerging and surfacing statuses and gliding speed of the underwater glider. To further study the buoyancy regulating system,[Methods] we carry out theoretical analysis and CFD for the underwater glider and its buoyancy regulating system to obtain the buoyancy regulating value,which is an important design parameter;develop a buoyancy regulating system with both oil outlet and oil return passages,that is,a high-pressure plunger pump for oil outlet in deep water and a low-energy gear pump for oil return in shallow water. We conduct the tests for the oil outlet and oil return characteristics and the energy consumption under different pressure conditions.[Results] The results show that the oil outlet is normal under the pressure of 2.5 MPa and the oil return is normal under atmospheric pressure. The developed test device can simulate the marine pressure in the actual operating environment of the underwater glider.[Conclusions] The study results can provide useful references for the engineering application of the buoyancy regulating system
She hui zi ben dui chu guo wu gong jia ting er tong de she hui xin li fa zhan ying xiang: ji yu Zhongguo Yanji Shi de yan jiu = Effects of social capital on psychosocial development of children whose parent(s) work abroad : a study in Yanji City, China.
No full text近几十年来，出国务工在一些国家和地区越来越成为普遍现象。在全球化的影响下，宏观层面的劳动力资本流动影响着出国务工家庭的个人生活。为了了解出国务工家庭儿童的社会心理发展情况，本研究运用社会资本和抗逆力理论，建立生态系统模型，从积极的视角分析四个方面的社会资本对不利环境儿童的社会心理发展的作用。现有研究表明，与完整家庭类型的儿童相比，出国务工家庭儿童的社会心理发展的影响是否具有差异性尚不明确，在不同地区、不同人群有着不同的结果。据此，本研究关注不同情景变项中的环境因素，强调因情境而释放的积极力量而促使儿童产生积极的发展结果。文章提出即使面对父母缺失，出国务工家庭儿童仍然可以通过环境中的保护性因素的积极作用而表现出良好的社会心理发展结果。基于此，研究以社会资本和抗逆力作为考察儿童成长环境的社会和个人所具有的优势资源，讨论不同情境中的社会资本──家庭社会资本、学校社会资本、朋辈社会资本和社区社会资本和个人所具有的抗逆力对儿童社会心理发展的积极作用，并且通过对比分析，验证出国务工家庭的儿童和完整家庭的儿童对于社会资本作用机制和通过抗逆力的作用机制是否对于社会心理发展结果具有差异性。本研究采用后实证主义研究范式，运用定量研究方法，通过横断面问卷调查方法，收集中国吉林省延吉市来自完整家庭与出国务工家庭的儿童社会心理发展情况。运用T-test和结构方程的统计分析方法，进行均值检验、路径分析和多群组比较分析。研究表明，延吉市出国务工的现象较为普遍且以朝鲜族家庭居多。与以往研究一致，本文发现家庭、学校、朋辈和社区社会资本对儿童社会心理的发展具有积极的预测作用，而抗逆力在社会资本与社会心理发展的过程中起到了中介作用。家庭始终是影响儿童发展最为重要的场所；相对于出完整家庭的儿童，延吉市出国务工家庭的儿童在社会资本、抗逆力方面处于弱势地位，并且这些儿童成长的优势资源的欠缺可能是来自于因父母务工而造成的父母缺失的影响，但社会资本的欠缺并未带来两群组的儿童在社会心理发展水平的不同作用机制。据此，我们有理由相信，可以通过社会资本建设和抗逆力的培养，提高出国务工家庭儿童的社会心理发展水平。本研究运用社会资本理论和抗逆力建构社会生态系统模型，从儿童优势视角将社会因素与个人因素相结合，对于分析处境不利儿童具有重要的理论意义。而且，本研究扩展了社会资本在中国情景的适用性。另外，在社会资本理论的指导下，分析出国务工家庭儿童的社会心理发展为相关社会政策的制定、社会服务的开展提供宝贵的指导意见。最后，文章指出未来需要定性研究方法理解出国务工家庭儿童的经历，运用纵贯研究设计进一步探讨社会资本在不同人群和社会情景中的功能。In recent decades, workers coming from overseas have become a common phenomenon in some countries and regions. Under the influence of globalization, the flow of labor capital at the macro-economic level is affecting the personal life of the families of those working overseas. In order to understand the psychosocial development of the children who are left behind when one or both parents work abroad, this study employs social capital theory and resilience theory, and builds an ecological system model from a positive perspective to analyze in four dimensions the effects of social capital on the psychosocial development of children in unfavorable environments.Existing studies show that the significant differences in psychosocial development between children who have a parent or parents working abroad and children in intact families are still ambiguous, and different regions and populations have different situations. This study focuses on the children's environment in different social contexts and emphasizes the positive effects of the social contexts that can enhance the psychosocial development of children. Looking at the situation from such a perspective, this study believes that there are protective factors that can cause children who have one or both parents working abroad to manifest favorable psychosocial development outcomes despite parental absence. Based on this assumption, this thesis regards social capital and resilience as advantageous resources embedded in social contexts and individual ability. It explores the positive influence of family social capital, school social capital, peer social capital and community social capital in different social contexts and the effect of the resilience of individual ability on the psychosocial development of children. Moreover, it tested whether or not the effects of social capital and resilience on the psychosocial development of children were different between children who have a parent or parents working abroad and children who live in intact families.Adopting the paradigm of post-positivism, the researcher used quantitative research methods and conducted a cross-sectional survey to collect data from Yanji City, Jilin Province, China. This thesis was designed to explore the impacts of social capital and resilience on the psychosocial development of children who have one or both parents working abroad. The data was analyzed using T-test and structural equation modeling methods to test differences in means and to do path analysis and multi-group analysis.This study found that working abroad is a common practice for Yanji residents, especially for those of Korean ethnicity. In alignment with previous findings, it indicated that family, school, peer and community social capital can positively predict the psychosocial development of children; resilience has a mediating effect on the relationship between social capital and the psychosocial development of children. One of our most important findings is that family plays the dominant role in the development of children. In addition, compared to children living in intact families, children who have one or both parents working abroad are disadvantaged with respect to social capital and resilience, and the deficiency in these resources may arise from the absence of parents who work abroad. Besides the above findings, the multi-group analysis showed that the effects of social capital on resilience and psychosocial development between the two groups are identical. This means it is reasonable to improve the psychosocial development of children through social capital building and resilience motivation regardless of whether or not one or both of their parents work abroad.In this thesis, the researcher constructed an ecological framework based on social capital and resilience theories in order to combine the positive factors from social contexts and individual ability, which is theoretically meaningful for the study of the development of disadvantaged children. Meanwhile, this study advanced the use of social capital theory in a Chinese context, hence potentially fortifying its universal applicability. In addition, by using the theory of social capital to analyze the psychosocial development of children who are left behind when their parents work abroad, this study has valuable implications for policy making and social service design. The study also informs future research to employ qualitative research methods to understand the experience of those left-behind children and adopt longitudinal designs to examine the functioning of social capital within various populations and socio-cultural contexts.Detailed summary in vernacular field only.Detailed summary in vernacular field only.Detailed summary in vernacular field only.Detailed summary in vernacular field only.Detailed summary in vernacular field only.欒卉.Thesis (Ph.D.) Chinese University of Hong Kong, 2014.Includes bibliographical references (leaves 209-251).Abstracts also in English.Luan Hui
Scientific substantiation of the regional development strategy of the PRC in the second half of the XX century (based on the works of Chinese economists Ma Hong and Li Jingwen)
No full textBased on the analysis of the main works of famous Chinese scholars Ma Hong and Li Jingwen, the article presents scientific conclusions on the implementation of the strategy of socio-economic regional development of the PRC in the second half of the XX century in the following areas: a comprehensive assessment of the policy of reforms and openness, analysis of rationalization of economic management systems, research on inter-regional competition and prospects for the development of a socialist commodity economy. In Chinese historiography, the issues of strategic socio-economic transformations are reflected in the monographs of various scholars of historians, economists, geographers An Husen, Wang Shenjing, Ye Yumin, Ren Baoping, Liu Weidong, Sun Jiuwen, Sun Shangqing, Wu Shuqing, Cao Yuhoy, Jing Yuejun, Zhang Wenzhong, Zhang Xiaolei and Cheng Bidin, as well as on the pages of magazines such as Jingji Guancha (Economic Observation), Zhongguo Gune Jinji (Industrial Economy of China), Chengshi Guihua (Urban Planning), Quuyu Jinji Pinglun (Regional Economic review), Guotszi venti Yanji (Research International), Zhongguo shi di byantszyan Yanji (Study of history and geography of Chinas border areas). The purpose of this article is to identify the features of the scientific justification of socio-economic transformations in China in the second half of the XX century Chinese scholars economists Ma Hong and Li Jingwen. To achieve this goal, using the method of logical and concrete analysis of the main works of leading Chinese economists, patterns were identified in the scientific justification for the implementation of the strategy of socio-economic regional development of the PRC in the second half of the XX century. At the end of the XX century, Chinese economists in their research focused on the study of regional features of implementation of the policy of reform and openness, while using the results of their research activities in the process of managing regional economic projects of the PRC
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