28,782 research outputs found

    The terfenadine event

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    MS-150-10-f01-005: Letter to Lin, 1891

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    1 handwritten letter on stationary, 1 page.Letter to Lin ?, dated November 30, 1891. On Russell House, Detroit, Michigan stationar

    Two-dimensional LC-MS/MS to enhance ceramide and phosphatidylcholine species profiling in mouse liver

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    A two-dimensional (2D) hydrophilic interaction liquid chromatography (HILIC) and reverse-phase (RP) liquid chromatography (LC) system coupled with triple-quadrupole mass spectrometry (MS) was developed to comprehensively profile ceramides and phosphatidylcholine in extracted biological samples. Briefly, the 2D HILIC-RPLC systemused a silica HILIC column operated in the first dimension to distinguish the lipid classes and a BEH C-18 column operated in the second dimension to separate the lipid species of the same class. The regression linearity of each lipid was satisfactory in both systems; however, the absolute matrix effect factor was reduced in 2D LC-MS/MS system. Limits of detection of 2D LC-MS/MS system were 2- to 3-fold lower compared with one-dimensional RPLC-MS/MS. The recovery from the sample ranged from 84.5 to 110%. To summarize, the developed method was proven to be accurate and producible, as relative standard deviations remained <20% at three spiked levels. The efficiency of this newly developed system was applied to measure changes of lipids in the liver of mice after naphthalene treatment. Orthogonal projection to latent structures-discriminant analysis discriminated the lipids from control and the treatment group. We concluded that 2D LC-MS/MS is a promising method to assist lipidomic studies of complex biological samples. Copyright (C) 2014 John Wiley & Sons, Ltd

    Personal Letter from Lin Gale to George Carmichael, April 18, 1932

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    Personal Letter from Lin Gale to George Carmichael, April 18, 1932. MS/150/9 Adele and Richard Carmichael Collection. Box 1, Series 1, Folder 1. Valdosta State University Archives and Special Collections. 1 PDF, 1 scans.Personal Letter from Lin Gale to George Carmichael, April 18, 1932. MS/150/9 Adele and Richard Carmichael Collection. Box 1, Series 1, Folder 1. Valdosta State University Archives and Special Collections

    Ms. Courtney Chartier, RWWL AUC, August 2011

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    This video is a conversation with Ms. Courtney Chartier. Ms. Chartier talks about her work on the "New Georgia Encyclopedia" and "Online Voter Education Project." Andrea Jackson, AUC Woodruff Library, is the interviewer

    Ms. Neely Terrell, RWWL AUC, March 2012

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    This video is a conversation with Ms. Neely Terrell. Ms. Terrell talks about her book, "Super Singles Activate". Anthony Kinsey and Jahnesta Horney, AUC Woodruff Library, are the interviewers

    Ms. Felesha Love, Spelman College, January 2016

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    This video is a conversation with Felesha Love. Ms. Love talks about her book, "Brave Leap to Freedom: Integrating Mind, Body, and Spirit to Cultivate Healthy Relationships". Jordan Moore, AUC Woodruff Library, is the interviewer
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