2,985 research outputs found
Capitalism Denied with Chinese Characteristics
No full textKerswell T, Lin JN. Capitalism Denied with Chinese Characteristics. Socialism and Democracy. 2017;31(2):33-52
Chinese Politics and Labor Movements
No full textLin JN. Chinese Politics and Labor Movements. Politics and Development of Contemporary China . Cham: Springer; 2019
Depilatory cream enhances transdermal drug delivery by disrupting both intracellular keratin matrix and intercellular lipid organization of human stratum corneum
No full textAdenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength
No full textDuring the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a mature state with decreased probability of release, smaller unitary amplitude and synaptic facilitation. Using paired recordings, we demonstrate that the developmental shift in release probability at synapses between rat somatosensory layer 5 thick-tufted pyramidal cells is due to a higher and more heterogeneous activation of presynaptic adenosine A1 receptors. Immature synapses under control conditions exhibited distributions of CV, failure rate and release probability that were almost coincident with the A1 receptor blocked condition; however, mature synapses under control conditions exhibited much broader distributions that spanned those of both the A1 receptor agonised and antagonised conditions. Immature and mature synapses expressed A1 receptors with no observable difference in functional efficacy and therefore the heterogeneous A1 receptor activation seen in the mature neocortex is due to increased adenosine concentrations that vary between synapses. Given the central role demonstrated for A1 receptor activation in determining synaptic amplitude and the statistics of transmission between mature layer 5 pyramidal cells, the emplacement of adenosine sources and sinks near the synaptic terminal could constitute a novel form of long-term synaptic plasticity
The dynamics of single spike-evoked adenosine release in the cerebellum
No full textThe purine adenosine is a potent neuromodulator in the brain, with roles in a number
of diverse physiological and pathological processes. Modulators such as adenosine are difficult
to study as once released they have a diffuse action (which can affect many neurones) and,
unlike classical neurotransmitters, have no inotropic receptors. Thus rapid postsynaptic currents
(PSCs) mediated by adenosine (equivalent to mPSCs) are not available for study. As a result
the mechanisms and properties of adenosine release still remain relatively unclear. We have
studied adenosine release evoked by stimulating the parallel fibres in the cerebellum. Using
adenosine biosensors combined with deconvolution analysis and mathematical modelling, we
have characterised the release dynamics and diffusion of adenosine in unprecedented detail.
By partially blocking K+ channels, we were able to release adenosine in response to a single
stimulus rather than a train of stimuli. This allowed reliable sub-second release of reproducible
quantities of adenosine with stereotypic concentration waveforms that agreed well with predictions
of a mathematical model of purine diffusion. We found no evidence for ATP release
and thus suggest that adenosine is directly released in response to parallel fibre firing and does
not arise from extracellular ATP metabolism. Adenosine release events showed novel short-term
dynamics, including facilitated release with paired stimuli at millisecond stimulation intervals
but depletion-recovery dynamics with paired stimuli delivered over minute time scales. These
results demonstrate rich dynamics for adenosine release that are placed, for the first time, on a
quantitative footing and show strong similarity with vesicular exocytosis
A high-performance CMOS power amplifier for 60 GHz short-range communication systems
No full text[[abstract]]A 60 GHz power amplifier for direct-conversion transceiver using standard 90 nm CMOS technology is reported.The power amplifier comprises three cascaded common-source stages with inductive load and inter-stage matching. To increase the saturated output power (Psat) and power-added efficiency (PAE), the output stage adopts a two-way power dividing and combining architecture. Instead of the area-consumed Wilkinson power divider and combiner, miniature low-loss LC power divider and combiner are used. This in turn results in further Psat and PAE enhancement. Over the 57 approximate to 64 GHz frequency band of interest, the power amplifier consumes 44.4 mW and achieves power gain (S21) of 12.04 +/- 1 dB, input-port input return loss (S11) of 6 to 9.4 dB, output-port input return loss (S22) of 10.4 to 26.4 dB, and reverse isolation (S12) of 29.2 to 30.6 dB. At 60 GHz, the power amplifier achieves Psat of 11.4 mW and maximum PAE of 15.8%. To the authors' knowledge, this is the best PAE ever reported for a 60 GHz CMOS power amplifier. In addition, the measured output 1-dB compression point (OP1 dB) is 6 dBm at 60 GHz. These results demonstrate that the proposed power amplifier architecture is very promising for 60-GHz short-range communication systems. (c) 2013 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:11551160, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27522[[note]]SC
The Belt and Road Initative: A New Zealand Appraisal
No full textYoung J, Lin JN. The Belt and Road Initative: A New Zealand Appraisal. Wellington: Victoria University of Wellington; 2018
60 GHz CMOS power amplifier with P-sat of 11.4 dBm and PAE of 15.8%
No full text[[abstract]]A 60 GHz power amplifier (PA) for a direct-conversion transceiver using standard 90 nm CMOS technology is reported. The PA comprises three cascaded common-source stages with inductive load and inter-stage matching. To increase the saturated output power (P-sat) and power-added efficiency (PAE), the output stage adopts a two-way power dividing and combining architecture. Instead of the area-consumed Wilkinson power divider and combiner, a miniature low-loss LC power divider and a combiner are used. This in turn results in further P-sat and PAE enhancement. Over the 57-64 GHz band of interest, the PA consumes 44.4 mW and achieves a power gain (S-21) of 12.04 +/- 1 dB. At 60 GHz, the PA achieves P-sat of 11.4 mW and a maximum PAE of 15.8%. To the authors' knowledge, this is the best PAE ever reported for a 60 GHz CMOS PA. These results demonstrate the proposed PA architecture is very promising for 60 GHz short-range communication systems.[[note]]SC
Do More Strikes Mean a Stronger Working Class's Agency: A Comparative Study in Post-Socialist China
No full textLin JN. Do More Strikes Mean a Stronger Working Class's Agency: A Comparative Study in Post-Socialist China. Journal of Labor and Society. 2017;20(1):85-106
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