1,721,011 research outputs found

    Solitary fibrous tumor of the orbit case report and review of the literature

    No full text
    BACKGROUND Solitary fibrous tumor (SFT), which usually presents in the pleura and is thought to be mesothelial in nature, has been recently discovered in extrapleural sites, including the orbit. Presently ultrastructural studies show absence of epithelial-mesothelial features, and reactivity of the tumor cells to CD34 antigen on immunohistochemical analysis suggests the mesenchymal origin of such tumors. CASE DESCRIPTION A 40-year-old woman had a 4-year history of progressive swelling of her right upper lid and a slow-growing palpable mass of the orbit. CT and MR imaging showed a well circumscribed, nonenhanced extraconal mass with mild erosion of the right orbital roof. The tumor was totally excised. Histological examination disclosed a spindle-cell tumor in a dense fibrous tissue. Immunohistochemistry showed positive staining for vimentin and CD34. We review the clinical, diagnostic, and surgical features of 22 orbital SFTs including the present case. CONCLUSIONS Orbital SFT generally pursues a slow, indolent, and nonaggressive course, reaches a size up to 4.5 cm, and can be cured by a single excision. It must be immunohistochemically differentiated from other spindle-cell tumors of the orbit. (C) 2001 by Elsevier Science Inc

    INCREASED LEVELS OF SEVERAL CYTOKINES IN ATOPIC PATIENTS WITH MILD ASTHMA.

    No full text
    To determine whether cytokines are generated in vivo in subjects with mild asthma, we have measured cytokines levels (il lalfa,lbeta,6,8,tnf) in lps-stimulated alveolar macrophage culture of eight atopic patients whith mild asthma in intercritical period, compared to four normal subjects as control group. significant levels of tnf, il lbeta, il 8, but not il 1 alfa and il6 were found in lps-stimulated alveolar macrophages culture in atopic patients versus control subjects
    corecore