387 research outputs found
Supplemental Material - Does rural tourism reduce relative poverty? Evidence from household surveys in western China
No full textSupplemental Material for Does rural tourism reduce relative poverty? Evidence from household surveys in western China by Peiying Dang, Linjing Ren, Jie Li in Tourism Economics</p
One Field of the Reception in Japan of the Stone Canal Pavilion Printing House Repaired Edition of Zhongyi Shuihu Zhuan: Kyokutei Bakin and Kita Seiro to a clue
No full textAs is generally well-known, a text of the Stone Canal Pavilion Printing House 石渠閣 (Shiquge) repaired edition of Zhongyi Shuihu Zhuan 忠義水滸傳 is possessed in the National Library of China 中國國家圖書館 however the same edition Hirata Shôji's 平田昌司 possession Zhongyi Shuihu Zhuan was discovered newly last year in Japan. The purpose of this paper is to find a clear relationship between the Stone Canal Pavilion Printing House repaired edition of Zhongyi Shuihu Zhuan, Hirata's possession Zhongyi Shuihu Zhuan and Kyokutei Bakin 曲亭馬琴, Kita Seiro 北靜廬. Through the consideration of handwriting document (letter, diary), writing (Shinpen suiko gaden 新編水滸畫傳) of Kyokutei Bakin, writing･manuscript of Kita Seiro, the marginal notes which is written in the Hirata's possession Zhongyi Shuihu Zhuan, and various Shuihu Zhuan 水滸傳 Printed books. The authentic evidence has not been yet gained, however it is sure that the characteristic of Li Zhuowu pingyue yibaihui 李卓吾評閲一百回 which Kyokutei Bakin's written is completely the same as the characteristic of Hirata's possession Zhongyi Shuihu Zhuan, and it is not impossible to adding the marginal notes to Hirata's possession Zhongyi Shuihu Zhuan using Japanese reprint (和刻本 Wakokubon) Zhongyi Shuihu Zhuan, Qishihuiben 七十回本 Shuihu Zhuan. It is more likely that these two books are the same
ホジェン語インタビューテキスト(1) : お産について
No full text資料・研究ノートHezhen is one of the Tungusic languages spoken by the Hezhen who are living in Heilongjiang Province, China. Their population currently is about 4600, and 10 or less of them can speak the native Hezhen language according to the author’s survey. This paper presents an interview text written by the author based on an interview taken at Bacha village, Heilongjiang Province, China on September 4th, 2008. The interviewee is Zhang Shuzhen, a Kilen dialect speaker who was born in 1926 and now is living in Bacha village. The interview was taken as follows: The speaker answered questions asked by the author in Hezhen language, some of the questions and the answers are mixed with Mandarin. The interview was recorded by the author. After the interview, the author listened to the interview record and transcribed it into a text. The author checked and improved the transcription together with the interviewee by listening to the audio data on August 26th and 27th, 2011. The length of the interview is about 31 minutes. Ms. Zhang told her experience in her 20s and 30s (from the latter half of 1940s to 1960s) about childbirth, recuperation after that, hardship of raising children, relationship between daughter-in-laws and mother-in-laws, and the rules for women at that time
Sphere-Shaped Hierarchical Cathode with Enhanced Growth of Nanocrystal Planes for High-Rate and Cycling-Stable Li-Ion Batteries
No full textHigh-energy and high-power Li-ion
batteries have been intensively
pursued as power sources in electronic vehicles and renewable energy
storage systems in smart grids. With this purpose, developing high-performance
cathode materials is urgently needed. Here we report an easy and versatile
strategy to fabricate high-rate and cycling-stable hierarchical sphered
cathode Li1.2Ni0.13Mn0.54Co0.13O2, by using an ionic interfusion method. The sphere-shaped
hierarchical cathode is assembled with primary nanoplates with enhanced
growth of nanocrystal planes in favor of Li+ intercalation/deintercalation,
such as (010), (100), and (110) planes. This material with such unique
structural features exhibits outstanding rate capability, cyclability,
and high discharge capacities, achieving around 70% (175 mAh g–1) of the capacity at 0.1 C rate within about 2.1 min
of ultrafast charging. Such cathode is feasible to construct high-energy
and high-power Li-ion batteries
TPACK and Inquiry competence in Early Childhood Education and in-service teacher support through continuous professional development (CPD)
No full textDifferential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice
No full textLumbar splanchnic (LSN) and sacral pelvic (PN) nerves convey different mechanosensory information from the colon to the spinal cord. Here we determined whether these pathways also differ in their chemosensitivity and receptor expression. Using an in vitro mouse colon preparation, individual primary afferents were tested with selective P2X and transient receptor potential vanilloid receptor 1 (TRPV1) receptor ligands. Afferent cell bodies in thoracolumbar and lumbosacral dorsal root ganglia (DRG) were retrogradely labelled from the colon and analysed for P2X3- and TRPV1-like immunoreactivity (LI). Forty per cent of LSN afferents responded to alpha,beta-methylene adenosine 5'-triphosphate (alpha,beta-meATP; 1 mm), an effect that was concentration dependent and reversed by the P2X antagonist pyridoxyl5-phosphate 6-azophenyl-2',4'-disulphonic acid (PPADS) (100 microm). Significantly fewer PN afferents (7%) responded to alpha,beta-meATP. Correspondingly, 36% of colonic thoracolumbar DRG neurones exhibited P2X3-LI compared with only 19% of colonic lumbosacral neurones. Capsaicin (3 microm) excited 61% of LSN afferents and 47% of PN afferents; 82% of thoracolumbar and 50% of lumbosacral colonic DRG neurones displayed TRPV1-LI. Mechanically insensitive afferents were recruited by alpha,beta-meATP or capsaicin, and were almost exclusive to the LSN. Capsaicin-responsive LSN afferents displayed marked mechanical desensitization after responding to capsaicin, which did not occur in capsaicin-responsive PN afferents. Therefore, colonic LSN and PN pathways differ in their chemosensitivity to known noxious stimuli and their corresponding receptor expression. As these pathways relay information that may relate to symptoms in functional gastrointestinal disease, these results may have implications for the efficacy of therapies targeting receptor modulation.Stuart M Brierley, R Carter, W Jones III, Linjing Xu, David R Robinson, Gareth A Hicks, G. F Gebhart and L. Ashley Blacksha
Platelet-lymphocyte cross-talk in atherogenesis : experimental studies on platelet-regulated lymphocyte adhesion and CD4+ T cell activation
No full textAtherosclerosis is an inflammatory and thrombotic disease. Platelets and lymphocytes, especially CD4+ T cells, are indispensable players during the initiation and progression of atherosclerotic lesion formation. During the early stage of atherogenesis, lymphocytes are generally thought to be recruited from arterial blood flow. It is, however, not clear how they are recruited. Platelets can regulate various functional aspects of CD4+ T cells, but the mechanisms of platelet-CD4+ T cell interactions have not be well defined. Therefore, aims of the present thesis work are to investigate how platelets influence lymphocyte adhesion under arterial flow conditions, and how platelets regulate CD4+ T cell functions.Platelet-supported lymphocyte adhesion was first investigated using reconstituted human blood and a collagen-coated parallel-plate flow chamber. Adhered platelets supported lymphocyte adhesion under arterial flow conditions (e.g., 500 s-1), which involved multiple adhesion molecules (e.g., P-selectin, CD40L, and GPIIb/IIIa). Platelet-dependent lymphocyte adhesion was selective among larger CD4+ and CD8+ T cells, and small B cells. In vivo model of arterial thrombosis confirmed that arterial thrombi supported lymphocyte recruitment, and that platelet GPIIb/IIIa blockade prevented thrombus formation and subsequently abolished lymphocyte recruitment.We continued to study how platelets enhance lymphocyte adhesion on subendothelial matrix protein (SEMP)-coated surface under arterial flow conditions by using Cone and Plate(let) analyser (CPA). Collagen markedly, fibrinogen and VWF mildly provoked platelet deposition that proportionally enhanced lymphocyte adhesion. The data confirmed that platelets selectively enhance adhesion of large CD4+ and CD8+ T cells and NK cells, and of small B cells. The lymphocyte adhesion positively correlates with their platelet conjugating potential and expression of PSGL-1, Mac-1, and CD40L.Platelet-regulated CD4+ T cell function was investigated in autologous human platelet-CD4+ T cell co-cultures. Platelets attenuated CD4+ T cell proliferation, but enhanced activation of Th1/Th17/Treg cells. The enhancements were exerted by both direct cell-cell contact and platelet-derived soluble mediators PF4, RANTES, and TGF?. The enhancements were shown as increased CD4+ T effector cell phenotypes and corresponding cytokine production. Dynamics of platelet-regulated CD4+ T cell activation were also monitored. Platelets constantly promoted Treg cell activation, but exerted a biphasic regulation on Th1/Th17 activation, namely a transient enhancement followed by a secondary suppression. The distinct regulations were achieved by a selective, TGF?-mediated inhibition of FoxP3– T cell proliferation.Together, the thesis work has elucidated novel mechanisms of platelet-regulated CD4+ T effector cell responses. Platelets selectively enhance lymphocyte adhesion under arterial flow conditions, and regulate distinct dynamics of Th1/Th17/Treg cell activation.List of scientific papersI. Hu H, Zhu L, Huang Z, Ji Q, Chatterjee M, Zhang W, Li N. Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus. Thromb Haemost. 2010; 104(6):1184-92. https://doi.org/10.1160/TH10-05-0308 II. Gerdes N, Zhu L, Ersoy M, Hermansson A, Hjemdahl P, Hu H, Hansson GK, Li N. Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans. Thromb Haemost. 2011; 106(2):353-362. https://doi.org/10.1160/TH11-01-0020 III. Spectre G, Zhu L, Ersoy M, Hjemdahl P, Savion N, Varon D, Li N. Platelets selectively enhance lymphocyte adhesion on subendothelial matrix under arterial flow conditions. Thromb Haemost. 2012;108(2):328-337 https://doi.org/10.1160/TH12-02-0064 IV. Zhu L, Huang Z, Stålesen R, Hansson GK, Li N. Platelets provoke distinct dynamics of immune responses of different CD4+ T cell subsets via selective regulations of cell proliferation. [Manuscript]</p
Ultrathin Spinel Membrane-Encapsulated Layered Lithium-Rich Cathode Material for Advanced Li-Ion Batteries
No full textLack of high-performance cathode
materials has become a technological
bottleneck for the commercial development of advanced Li-ion batteries.
We have proposed a biomimetic design and versatile synthesis of ultrathin
spinel membrane-encapsulated layered lithium-rich cathode, a modification
by nanocoating. The ultrathin spinel membrane is attributed to the
superior high reversible capacity (over 290 mAh g–1), outstanding rate capability, and excellent cycling ability of
this cathode, and even the stubborn illnesses of the layered lithium-rich
cathode, such as voltage decay and thermal instability, are found
to be relieved as well. This cathode is feasible to construct high-energy
and high-power Li-ion batteries
Stem cells with a view: a look inside a retinal ciliopathy
No full textComment on: Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups. [Cell Stem Cell. 2016
Refinement of symmetrical Nash equilibrium for generalized second-price mechanism in sponsored search advertising
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