1,721,036 research outputs found
Concordanza e discordanza tra segni clinici e reperti anatomopatologici in 50 cavalli venuti a morte per colica.
No full textUn caso di osteosarcoma fibroblastico omerale in un leone (Panthera leo)
No full textL’osteosarcoma è il tumore osseo più frequente in tutte le specie animali, uomo compreso. Rari sono i casi di osteosarcoma spontanei negli animali esotici e c.d. non “convenzionali”. Scopo di questo lavoro è quello di descrivere un caso di osteosarcoma fibroblastico omerale in un leone, detenuto in cattività presso un parco privato della provincia di Perugia. L’animale di sesso femminile (non sterilizzato), di circa 16 anni di età, di circa 200 Kg. di peso e regolarmente vaccinato fino ai 5 anni di età, ha manifestato i primi sintomi di malattia circa 9 mesi prima della sua morte. L’esame macroscopico della massa neoplastica, localizzata a carico del terzo prossimale dell’omero di dx mostrava un tumore di dimensioni di 26 x 12 x 10 cm, a superficie liscia irregolare, di colore brunastro, di consistenza ferma e con superficie di taglio dello stesso colore rosso scuro irregolare, di aspetto multilobulare, poco vascolarizzata e non emorragica e con aree di focale calcificazione. La crescita espansiva del tumore coinvolgeva ed invadeva anche i compartimenti epifisari circostanti, la membrana sinoviale, la capsula articolare ed i legamenti. Istologicamente il tumore appariva essenzialmente costituito da una popolazione di cellule sarcomatose, caratterizzate da forma fusiforme, pleomorfismo marcato, ipercromatismo nucleare con nucleoli prominenti e indice mitotico di media entità. Sulla base delle caratteristiche istopatologiche del tumore la diagnosi istopatologica definitiva è stata quella di osteosarcoma fibroblastico omerale.
Osteosarcoma is the most frequent malignant bone tumor in all animals species and rarely is described in exotic and “non conventional” animals. A case of spontaneous humeral fibroblastic osteosarcoma in a lion (Panthera lion) housed in a private park in Perugia is reported. Based on the rate growth of the lesion and histopathological findings a final diagnosis of fibroblastic osteosarcoma was given
PMWS (Postweaning Multisystemic Wasting Syndrome) In Central Italy: Histopathological, Immunohistochemical and Ultrastructural Findings
No full textWe describe the presence of Porcine circovirus 2 (PCV-2) in thirteen pigs
necropsied in Department of Biopathological Sciences and Hygiene of Animal
and Alimentary Productions in Perugia. Sistemic lymphadenopathy, sometimes
haemorrhagic and necrotic, spleen enlarged thymus atrophic, lungs collapse and
consolidated, were the principal gross findings. The most consistent histological
lesion was a moderate to severe lymphocellular depletion in lymphoid organs,
syncytial giant cell formation, and intracytoplasmic inclusion bodies in
macrophages. PCV-2 was immunohistochemically detected in all pigs with
PMWS. Electron microscopy investigations demonstrated viral particles
compatible with Porcine PCV-2
Lesioni nel cavo orale del gatto: Indagine retrospettiva su 228 casi (2005-2010)
No full textIntroduction - Oral diseases are common in cats and can appear as ulcerative and proliferative tumor-like lesions, both inflammatory or truly neoplastic; in this regard we performed a retrospective review of feline oral lesions with emphasis on pathological differential findings. Materials and methods - We revaluated 228 routinely processed histological samples from feline oral cavity. Results - Most of the diagnostic samples were represented by non tumoral inflammatory lesions (61% of the samples), with chronic lymphoplasmacytic stomatitis overrepresented (71.2% of inflammatory lesions); tumors were 25% of the total, most of them being squamous cell carcinomas (49%). In 85/228 cases anamnesis reported erosive-ulcerative lesions; in 79/228 cases anamnesis reported a mass, proliferation or tumor-like lesion, but only in 30 of these cases (38%) the final diagnosis was consistent with neoplasia. Discussion - Evidence from our data is that although neoplasia often present as a mass or proliferative lesions, in the majority of cases oral masses are non neoplastic (inflammatory); on the other hand, ulcerative lesions can be both inflammatory and neoplastic. Only histological examination can allow a final diagnosis of feline oral nodular masses
Fibroblastic osteosarcoma in a lion (Panthera leo)
No full textThis report describes a case of spontaneous fibroblastic osteosarcoma in the humerus of a lion from a private park in Perugia, Italy. The tumor had an irregular, smooth, brown surface and a generally firm, rubbery consistence with gritty to hard areas interspersed. The mass was poorly vascularized with areas of necrosis at the periphery. The cut surface showed a multilobulated mass that had breached the humeral cortex, with periosteal production of reactive bone. The mass invaded the epiphysis, the synovial membrane, the joint capsule and ligaments. A mild hemorrhagic effusion appeared in the joint space. Clinical signs, gross and histopathologic findings are described in this rare case of a malignant bone tumor
Feline oral squamous cell carcinoma: an ‘osteogenic’ type? - 26th Annual Meeting of the European Society of Veterinary Pathology
No full textUn caso di sospetta malformazione vertebrale complessa (CVM) in un vitello frisone di 6 mesi
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