1,721,064 research outputs found
Bone tumors in domestic animals (comparative clinical pathology)
No full textThis book comparatively examines the etiopathogenetic, clinical-pathological, diagnostic and therapeutic strategies of the main bone tumors of domestic animals
Expression of Bcl-2 in canine osteosarcoma
No full textOsteosarcoma (OS) is the most common primary malignancy of bone. It is responsible for 80-85% of the primary bone tumors affecting dogs and it is characterized by aggressive and invasive behavior, with a high metastatic potential. Several studies on cancer and related tumorigenesis, show an involvement of the mechanisms of programmed cell death and cell survival. Many signals seem to be involved in the related mechanism of autophagy and in particular, our interest is focused on the expression of a family of Bcl-2 that seems to be involved either in the control of biomolecular mechanisms like autophagy and apoptosis. In this study we investigated the expression of Bcl-2 in different cases of spontaneous canine osteosarcoma and the related preliminary results are described. We found Bcl-2 activity was increased in OS tissue compared to normal bone tissue. These results suggested that Bcl-2 activity may play an important role in the formation of OS and as a diagnostic for neoplastic activity. However, further research is needed to confirm the role of Bcl-2 activity in OS in canines
Ascites Syndrome in Broiler Chickens
No full textThe ascites syndrome (AS), also known as Pulmonary Hypertension Syndrome (PHS), can be a major problem in the poultry industry, especially in the case of poor-managed flocks. It is commonly accepted that AS/PHS is caused by increased pulmonary blood flow or increased resistance to flow in the lung. This condition may produce right ventricular hypertrophy (RVH), valvular insufficiency, increased systemic venous pressure and in the latest stages ascites. Interactions among genetic, environmental and dietary factors play a basic role in the determinism of AS/PHS. Interventions should be aimed at slowing down the body growth as the high metabolic rate is a major factor contributing to the susceptibility of broilers to ascites. In this light is particularly important the choice of a diet appropriate to growing period associated with genetic selection addressed to achieve high weight gain without increasing the incidence of AS/PHS
Biomolecular studies of the correlations between autophagic and apoptotic activity in the pathogenesis of major spontaneous cancer in domestic animals and human.
No full textPromotion of anticancer immune response by attenuated mutant strain of salmonella typhimurium devoid of the znuabc transporter
No full textIndagine retrospettiva sulla frequenza dell'osteosarcoma in campioni bioptici e chirurgici -
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