1,721,167 research outputs found
Local recurrence of colo-rectal cancer: Risk factors and preventive measures
No full textAbstract
The local recurrence of colo-rectal cancer, still represents the major reason for the failure of surgical treatment. Several risk-factors of recurrence can be identified and grouped in categories according to different criteria (anatomo-clinical histopathological, biological, technical). Some of them represent undoubtedly proved risk factors of local recurrence, such as advanced stage, distal location, DNA abnormalities, lymphovascular invasion, whereas others are still under investigations (immunology of the tumor, oncogenes, antigens, role of mesorectal excision, pelvic-lymphoadenectomy etc). The identification of risk factors of local recurrence in colo-rectal cancer is of utmost importance since relevant technological innovations in the field of surgical treatment (TEM, laparoscopy) and adjuvant treatment (intra-cavitary radiotherapy, chemotherapy, immunotherapy etc) need a precise evaluation of the patients to be applied successfully
Perianal acquired tufted angioma associated with pregnancy: Case report
No full textAbstract
Tufted angiomas are rare lesions described as slowly growing/spreading erythematous macules especially located in the upper trunk and neck. Herein we report the case of perianal location of a tufted angioma in a young pregnant woman. She came to our observation complaining of perianal pain accompanied by bleeding at defecation. A lesion resembling a perianal fissure was observed. Mild hypertonia of the internal sphincter was confirmed at manometry. After one week of ineffective medical treatment, surgery was planned at the end of the sixteenth week under local anaesthesia. The lesion was excised and a minimal sphincterotomy was performed; histopathology report described features of a tufted angioma. The pregnancy proceeded regularly, without anal symptoms, followed by normal vaginal delivery at the thirty-eighth week. This case showed three peculiar features: the association of tufted angioma and pregnancy, the perianal location, and the clinical appearance suggestive of an anal fissure. The clinical manifestation of a perianal tufted angioma, mimicking an anal fissure, is of utmost importance to the differential diagnosis and treatment plan, especially in a pregnant woman
Acute colonic dilatation associated with a painful anal fissure
No full textAbstract
We report the case of an elderly woman who developed acute colon dilatation as a consequence of a painful fissure of the anus with severe hypertonia. After having excluded mechanical aetiology, a lateral internal sphincterotomy was performed under local anaesthesia. The procedure cured the anal pain and, by facilitating normal bowel function, allowed resolution of abdominal symptoms. The aetiology of acute colonic dilatation in this patient may be related to the painful anal fissure and hypertonia. In the elderly, the presence of simple anal diseases may predispose to the occurrence of life-threatening complications, such as acute colonic dilatation
- …
