1,721,373 research outputs found
Nutrition: New challenges for a venerable vision
Full text linkNutrition: New challenges for
a venerable visio
Living in interesting times - Challenging protein metabolism in the era of the epidemiological shift
Full text linkThe recently released results of the Global Burden of Disease, Injuries, and Risk Factor study 2013 reveal that during the past 23 years, metabolic and behavioral risk factors, including high BMI, increased their impact on global mortality and disability-adjusted life-years [1]. These data highlight the importance of the investigation of the metabolic impact of specific nutrients and different eating behaviors on preserving and restoring the health of individuals and also populations
Senescence: A new kid in the block of the metabolic response to surgical trauma
No full text: Tumor growth is associated to chronic metabolic changes which inform the clinical phenotype and the outcome of patients with cancer. Surgery further triggers a cascade of acute neuro-immune responses leading to hypermetabolic and catabolic state. The metabolic mechanisms associated to surgical stress are well described. Preventive and therapeutic strategies have been developed, yet they appear not to benefit all surgical patients with cancer, even in the presence of a similar tumor type as well surgical procedures. Recent studies show that aging is associated with enrichment of senescent cells in different organs and tissues. Senescent cells are characterized by a specific senescence-associated secretory phenotype (SASP), which limits the potential for resilience of tissues and organs. Enhancement of the metabolic and functional recovery of patients with cancer undergoing surgery may therefore require additional therapies addressing SASP and senescent cells. Preliminary results obtained in experimental models recommend to further explore the role of senescence in mediating the metabolic changes and tissue resistance to efficient recovery
Reply - Letter to the Editor - Malnutrition: The kiss of grim reaper
Full text linkConducting a large, multicenter, prospective, randomized clinical trial poses a number of challenges. In particular, the successful
completion of the trial is based on devising a protocol which could
yield to clinically relevant answers yet no becoming so complex
and sophisticated to prevent centers' participation and patients'
enrollment. Consequently, the methodology of any trial reflects
the clinical questions it tries to address
Il ruolo e l’impiego degli integratori specifici nella dietoterapia di patologie croniche – Introduzione
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Research in nutritional science: providing evidence to the clinical relevance of nutrition.
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