1,721,069 research outputs found

    Chemical and spectroscopic properties of two fractionsof soil organic matter obtained by electro-ultrafiltration

    No full text
    A soil sample, collected from vertisol in southern Italy and containing 3.7% of organic carbon, was extracted and fractionated by electro-ultrafiltration using a relatively low electric field and negative pressure. Micropore filters (20000 Da and 100000 Da) were selected to obtain two fractions of soil organic matter. E 4/E 6 ratios and analysis data were in agreement with values of fulvic and humic acids as reported in the literature. FT-IR spectra showed high absorption values in the region of carboxylic acid groups and medium intensity peaks in the region of frequencies ascribed to aliphatic chain absorptions. 1H-NMR spectra showed a resolution of signals as good as those previously reported for organic fractions that had been chemically extracted

    In vitro release studies from curcumin-loaded inulin-graft-vitamin E (INVITE) mucoadhesive micelles

    Full text link
    In order to investigate the potential use of INVITE micelles for urinary tract infections, we tested the ability of INVITE micelles to entrap and release a hydrophobic model drug such as curcumin, known for its high antioxidant properties and we evaluated the micelles mucoadhesive properties. In particular, micelles from INVITE polymers, at different degrees of substitution in VITE (10, 20 and 40%), have been prepared by the direct dialysis method so obtaining three different micelle systems. The same systems have been further drug loaded with curcumin by using two different methods in order to evaluate the influence of loading methods on drug loading capacity. In vitro drug release studies and mucoadhesive properties in simulated physiological conditions were carried out aimed to verify whether this DDS could be good candidate for the treatment of UTI
    corecore