131,506 research outputs found
Prove di compressione ciclica su pilastri in c.a. confinati con staffe e/o con tessuti in fibra di carbonio
No full textThe paper shows main results of cyclic compression tests performed on R.C. columns confined by FRP jackets. The specimens are 250x250 mm square section columns, reinforced and unreinforced by steel bars and stirrups. Experimental results are compared with the analytical model performed by Braga-Laterza-Gigliotti (1998, 1999, 2001) that takes into account, at the same time, the confinement of FRP jackets and of the internal steel stirrups. The comparisons highlighted the good capability of the analytical model to evaluate the confined behaviour of the tested columns
Fondazione Giovanni Agnelli, Rapporto sulla scuola in Italia 2011, Laterza, Roma-Bari 2011
No full textRecensione al volume: Fondazione Giovanni Agnelli, Rapporto sulla scuola in Italia 2011, Laterza, Roma-Bari 201
Collotti E., a cura di, Fascismo e antifascismo. Rimozioni, revisioni, negazioni, Laterza, Roma-Bari 2000
No full textRecensione al volume: Collotti E., a cura di, Fascismo e antifascismo. Rimozioni, revisioni, negazioni, Laterza, Roma-Bari 200
Handover checklist: testing a standardization process in an Italian hospital
No full textDavide Ferorelli,1 Teresa Giandola,2 Mariangela Laterza,2 Biagio Solarino,2 Angela Pezzolla,3 Fiorenza Zotti,2 Alessandro Dell’Erba1 1Interdisciplinary Department of Medicine, 2Section of Legal Medicine, 3Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy Objectives: This study aimed to standardize and rationalize the handover, a critical and essential moment in common health care practices, through the realization of an efficient and standardized checklist, which could be used daily to ensure complete, thorough and effective handover. The principal purpose of the implementation of the handover is to reduce errors due to superficial and insufficient communication.Methods: The “operative group” defined the phases to the realization of the delineated aims: at first, the direct observation and the consequent realization of a handover checklist model and then, the experimental phases (trials). The handover checklist model was used for a month and it was daily and duly completed by the doctors who took part in the trial. To prove the success of the study, three questionnaires were distributed on different occasions.Results: Analyzing the answers to the questionnaires, the importance of the handover has come to light and that for the most part, the doctors consider it an essential and irreplaceable moment in daily health care work. Moreover, it became obvious that the use of the handover checklist guaranteed a considerable improvement in the traditional handover in terms of security, completeness, care continuity and clarity. The handover checklist was completely appreciated by the majority of the participant doctors who agree with the definitive introduction of it in their unit.Conclusions: Our study indicated the consistency of the handover checklist as an instrument to implement the handover and, indirectly, to improve the quality of the care. Keywords: clinical risk management, handover checklist, health care workers trainin
Chiarelli (Brunetto). — L'origine dell'Uomo. Biblioteca di Cultura Moderna Laterza. 1978
No full textFerembach D. Chiarelli (Brunetto). — L'origine dell'Uomo. Biblioteca di Cultura Moderna Laterza. 1978. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, XIII° Série. Tome 5 fascicule 4, 1978. p. 339
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Neural stem cell transplantation in central nervous system disorders: From cell replacement to neuroprotection
No full textPurpose of reviewTransplantation of neural stem/precursor cells (NPCs) has been proposed as a promising therapeutic strategy in almost all neurological disorders characterized by the failure of central nervous system (CNS) endogenous repair mechanisms in restoring the tissue damage and rescuing the lost function. Nevertheless, recent evidence consistently challenges the limited view that transplantation of these cells is solely aimed at protecting the CNS from inflammatory and neurodegenerative damage through cell replacement.Recent findingsRecent preclinical data confirmed that transplanted NPCs may also exert a 'bystander' neuroprotective effect and identified a series of molecules - for example, immunomodulatory substances, neurotrophic growth factors, stem cell regulators as well as guidance molecules - whose in-situ secretion by NPCs is temporally and spatially orchestrated by environmental needs. A better understanding of the molecular and cellular mechanisms sustaining this 'therapeutic plasticity' is of pivotal importance for defining crucial aspects of the bench-to-beside translation of neural stem cell therapy, that is route and timing of administration as well as the best cellular source. Further insight into those latter issues is eagerly expected from the ongoing phase I/II clinical trials, while, on the other hand, new cellular sources are being developed, mainly by exploiting the new possibilities offered by cellular reprogramming.SummaryNowadays, the research on NPC transplantation in neurological disorders is advancing on two different fronts: on one hand, recent preclinical data are uncovering the molecular basis of NPC therapeutic plasticity, offering a more solid rational framework for the design of clinical studies. On the other hand, pilot trials are highlighting the safety and feasibility issues of neural stem cell transplantation that need to be addressed before efficacy could be properly evaluated
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