603 research outputs found

    Association between benign thyroid disease and breast cancer: A single center experience

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    Background The relationship between breast cancer (BC) and thyroid disease (TD) is still controversial. The aim of the study was to investigate the possible coexistence of TD in patients with newly diagnosed BC and its correlation with BC clinical presentation with regard to menopausal status and stage of disease. Methods This is a retrospective cohort study of all patients treated for primary BC between 2014 and 2016 at the Breast Unit of Trieste University Hospital. Clinical charts and reports were reviewed for coexisting thyroid disorders (i.e. hyperthyroidism, hypothyroidism, benign TD, thyroid cancer, thyroid autoimmunity) and menopausal status at the time of BC diagnosis. Biomolecular profile, stage, and grading of BC were also evaluated. Results A total of 786 women and 7 men were included in the study. Co-presence of TD was found in 161(20.3%) cases: of these, 151(19.4%) patients presented benign TD and 10(1.3%) patients presented thyroid carcinoma. Thyroid autoimmunity was found in 51(32%) patients. Regarding thyroid function, 88(55%) patients had hypothyroidism, 19(12%) hyperthyroidism, and 54(33%) normal thyroid function. No statistically significant correlation was found between age and TD (p = 0.16), although TD was more common in women aged ≥60 years. Women with BC diagnosed at pre-menopausal age were more likely to have thyroid autoimmune diseases (45% vs. 29%, p = 0.05). No association was detected among BC molecular profiles with either thyroid autoimmunity (p = 0.26) or altered thyroid function (p = 0.63). High-grade BC was more frequent in women with hyperthyroidism (52.9%, p = 0.04), but the grading was independent from the presence of thyroid autoimmune disease (p = 0.87). BC stage was related to both thyroid autoimmunity (p = 0.04) and thyroid function (p < 0.001), with 55.2% of women affected by benign TD presenting with stage I BC and more aggressive BCs found in hypothyroid patients. Conclusions According our study results, patients with primary BC present a greater incidence of autoimmunity disorders, especially when diagnosed in the pre-menopausal setting. However, further prospective studies are required to definitively prove causality

    The Pottesman Collection in the British Museum. Early Dynastic and Sargonic administrative texts. With an Appendix on a Palmyrene Inscription

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    Edizione, trascrizione, traduzione e commento di un frammento di iscrizione palmirena inedita presente nella collezione Pottesman del British Museum (Appendice Agostini).The British Museum houses a small collection of six cuneiform tablets and a Palmyrene dedicatory inscription purchased in 1987 from the private collection of Solomon Pottesman. The aim of the present contribution is to provide a catalog of this lot and an edition of the so far unpublished cuneiform texts. In the appendix, Alessio Agostini added the edition of the Palmyrene inscription, which would have otherwise gone beyond the capabilities of the present author

    Recensione di Cecilia Falchini (2023). Ruperto di deutz - Un’intima familiarità. Antologia, Edizioni Qiqajon (Comunità di Bose), Magnano (Bi), 281 pp.

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    Review of Cecilia Falchini (2023). Ruperto di deutz - Un’intima familiarità. Antologia, Edizioni Qiqajon (Comunità di Bose), Magnano (Bi), 281 pp. Author: Alessio MagogaRecensione di Cecilia Falchini (2023). Ruperto di deutz - Un’intima familiarità. Antologia, Edizioni Qiqajon (Comunità di Bose), Magnano (Bi), 281 pp. Autor: Alessio Magog

    Handheld-Impedance-Measurement System with seven-decade capability and potentiostatic function

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    This paper describes design and test of a new impedance-measurement system for nonlinear devices that exhibits a seven-decade range and works down to a frequency of 0.01 Hz. The system is specifically designed for electrochemical measurements, but the proposed architecture can be employed in many other fields where flexible signal generation and analysis are required. The system employs an unconventional signal generator based on two pulsewidth modulation (PWM) oscillators and an autocalibration system that allows uncertainties of less than 3% to be obtained over a range of 1 kΩ to 100 GΩ. A synchronous demodulation processing allows the noise superimposed to the low-amplitude input signals to be made negligibl

    El Tlacuache Núm. 16 (2001). 16 Año 1 (2001) octubre. El Tlacuache

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    - ¿Entre la Guerra Santa y la Cruzada? por Aníbal Quijano. - Nuestro patrimonio desconocido por Teresita Loera y Anaite Monterforte. - El Yahutli por Margarita Avilés y Macrina Fuentes. - Haciendas por Carlos Fernando Alessio Robles

    El Tlacuache Núm. 19 (2001). 19 Año 1 (2001) noviembre. El Tlacuache

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    - Patrimonio cultural y monumento histórico: Tlayacapan un monasterio Agustino por Carlos Alessio Robles. - Nuestro patrimonio desconocido por Teresita Loera y Anaite Monterforte. - El Yauhtli por Margarita Avilés y Macrina Fuentes. - ¿Entre la Guerra Santa y la Cruzada? por Aníbal Quijano

    Il GEIE "italiano" tra impresa e società

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    A quasi trent’anni dall’emanazione del Regolamento comunitario 2137/1985 che ne segna la data di nascita, e a venticinque dalla effettiva possibilità di costituzione, il gruppo europeo di interesse economico (GEIE) è ancora percepito, nella migliore delle ipotesi, come una specie di “oggetto misterioso” nel panorama giuridico italiano ed europeo. Lo scopo di questo studio, che ha beneficiato del sostegno economico della Commissione Europea e della Provincia autonoma di Trento nell’ambito del Settimo Programma Quadro, Azione Marie Curie COFUND, progetto “TRENTINO”, è di tentare una riconduzione ragionata del GEIE a categorie che siano di maggiore familiarità per il giurista italiano, indagandone le problematiche principali (su tutte l’assenza del beneficio della responsabilità limitata dei membri per le obbligazioni assunte dal gruppo) ed offrendo ipotesi di soluzione

    El Tlacuache Núm. 53 (2002). 53 Año 2 (2002) agosto. El Tlacuache

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    - Patrimonio Cultural por B. Palavicini y S.Garza. - Nuestro patrimonio desconocido por Teresita Loera y Anaite Monterforte. - El Yauhtli por Margarita Avilés y Macrina Fuentes. - Patrimonio cultural: Legislación e historia por Carlos F. Alessio-Robles

    El Tlacuache Núm. 51 (2002). 51 Año 2 (2002) julio. El Tlacuache

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    - Las fronteras norte de Morelos por H. Rafael Gutierrez Y. - Nuestro patrimonio desconocido por Teresita Loera y Anaite Monterforte. - El Yauhtli por Margarita Avilés y Macrina Fuentes. - Patrimonio cultural: Legislación e historia por Carlos F. Alessio-Robles

    El Tlacuache Núm. 52 (2002). 52 Año 2 (2002) julio. El Tlacuache

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    - La cremación, técnica y rito funerario por Alma Graciela de la Cruz Sánchez. - Nuestro patrimonio desconocido por Teresita Loera y Anaite Monterforte. - El Yauhtli por Margarita Avilés y Macrina Fuentes. - Patrimonio cultural: Legislación e historia por Carlos F. Alessio-Robles
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